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| Title | Author | Subject | Description | Date | ||
|---|---|---|---|---|---|---|
| 1 |  | Comparison of 5 noncoding region primer sets in the detection of hepatitis C virus using reverse transcription polymerase chain reaction | Alleyn, Susan K. | Hepatitis C Virus; Genotypes; DNA | Two new sets of nested primers were designed for the 5' noncoding region (NCR) of the hepatitis C virus (HCV). One hundred seventy HCV genome sequences were retrieved from GenBank and aligned. A consensus sequence was then determined for primer selection. A protocol was developed to test for the hep... | 1995-08 |
| 2 |  | Determination of the six ApoE genotypes using an isolated probe-polymerase chain reaction technique combined with multiplexed unlabeled probes and high resolution melting analysis | Poulson, Matthew Dean | Analysis; DNA | Apolipoprotein E (ApoE) is a polymorphic glycoprotein consisting of 299 amino acids. ApoE is responsible for 5-15% of the total cholesterol level in the body and is strongly associated with coronary heart disease and specifically Type III hyperlipidemia. ApoE is also linked to Alzheimer's disease ... | 2006-08 |
| 3 |  | Development of a sensitive polymerase chain reaction assay for group A streptococci | Hsieh, Fen-Fen | Polymerase Chain Reaction; DNA | S. pyogenes causes many important human diseases. Rheumatic fever is a systemic inflammatory and nonsuppurative sequla of acute streptococcal pharyngitis that occurs in a small proportion of patients. One hypothesis for the pathogenesis of rheumatic fever was proposed in this thesis, that persistent... | 1995-12 |
| 4 |  | Electrochemical quantification of DNA using aluminum oxide membranes | Sharma, Rohit | DNA; Electrochemical; Extraction; PDMS; Quantification; Molecular biology; Genetics; Biomedical engineering | DNA extraction automation is a major concern in molecular diagnostics where processing of numerous and daily samples of blood represent a labor-intensive task and are difficult to automate. With the rapid growth in the area of DNA diagnostics, there is an urgent need for the development of a microsi... | 2013-05 |
| 5 |  | Genetic exchange among linear replicons of the lyme disease spirochete, Borrelia burgdorferi | Murphy, Maria A. | DNA; Linear Plasmids | Spirochetes of the genus Borrelia are unusual among members of the prokaryotic kingdom as they have a linear chromosome of 950±20 kb. Initial physical mapping studies of Borrelia species indicate that this linear chromosome is stable with the exception of some observed variability at the right end... | 1995-12 |
| 6 |  | Measurement of transforming growth factor beta one and extra domain A fibronectin gene transcription in rat acute glomerulonephritis by competitive polymerase chain reaction | Yu, Xiaohong | DNA; RNA | The histologic picture of glomerulonephritis is characterized by pathological accumulation of extracellular matrix with damaged glomeruli. Previous studies have demonstrated that increased production of mesangial matrix in rat acute glomerulonephritis is caused by increased expression of transformi... | 1993-12 |
| 7 |  | Molecular characterization of phylogenetic lineages within group B streptococcus | Detrick, Shauna | DNA; Alleles; Hyaluronidase | Serotype III group B streptococci (GBS) have previously been sub-classified by restriction digest pattern (RDP) typing into three RDP type: III-3, III-2, and III-1. RDP type III-3 strains were previously found to cause the majority of neonatal invasive disease among a collection of isolates from T... | 2002-05 |
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