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Neville, Roselyn | Constitutively activated AKT is not sufficient to keep cells alive following epithelial cell extrusion | The PI3 kinase (PI3K)/AKT signaling pathway regulates many fundamental behaviors of the cell. If any of the key members of this pathway are deregulated, it can lead to malignant changes in the cell. AKT enhances the survival of cells by inhibiting pro-apoptotic processes, and promoting pathways for ... | PI3K/AKT - Chemistry; Cancer metastasis | 2014-05 |
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