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CreatorTitleDescriptionSubjectDate
326 Couldwell, William T.Inhibition of growth of established human glioma cell lines by modulators of the protein kinase-C systemThe protein kinase-C (PKC) second messenger system contributes to regulation of cell growth and differentiation. This study was undertaken to examine the effects of modulators of the PKC enzyme system on the state of differentiation and proliferation rates of human gliomas in vitro. The administrat...Protein kinase C; Phorbol ester; Cell proliferation; Tumor cell growth; Astrocyte; Glioma; Immunohistochemistry1990
327 Varner, Michael W.Intergenerational predisposition to operative delivery.OBJECTIVE: To determine the risk of cesarean delivery for women who themselves were born via operative delivery. METHODS: A linked data base was constructed between the birth certificates of individuals born in Utah during 1947-1957 (parental cohort) and who subsequently became a parent of offspring...Cesarean Section; Cohort Studies; Delivery, Obstetric; Obstetric Labor Complications1996-06
328 Mitchell, Joyce A.Predicting phenotypic severity of uncertain gene variants in the RET Proto-OncogeneAlthough reported gene variants in the RET oncogene have been directly associated with multiple endocrine neoplasia type 2 and hereditary medullary thyroid carcinoma, other mutations are classified as variants of uncertain significance (VUS) until the associated clinical phenotype is made clear. Cur...2011-01-01
329 Varner, Michael W.; Hatasaka, Harry H.Recurrent pregnancy loss.Recurrent pregnancy loss is a frustrating clinical dilemma for both patients and physicians because, in most cases, causes are nebulous and few treatments with proven benefit can be offered. Involved, expensive tests have frequently been proposed and their use has often filtered into clinical practi...Recurrent Pregnancy Loss; Uterus/abnormalities; Chromosome Disorders; Abortion, Habitual1994-06
330 Warner, Homer R.Role of the Computer in Coronary CareBiomedical Informatics1972
331 Dailey, Andrew T.Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 4: Radiographic assessment of fusion statusThe ability to identify a successful arthrodesis is an essential element in the management of patients undergoing lumbar fusion procedures. The hypothetical gold standard of intraoperative exploration to identify, under direct observation, a solid arthrodesis is an impractical alternative. Therefore...2014-01-01
332 Bernstein, Paul S.Skin carotenoid status measured by resonance Raman spectroscopy as a biomarker of fruit and vegetable intake in preschool childrenBackground/Objective: Dietary assessment in children is difficult, suggesting a need to develop more objective biomarkers of intake. Resonance Raman spectroscopy (RRS) is a noninvasive, validated method of measuring carotenoid status in skin as a biomarker of fruit/vegetable intake. The purpose of t...2012-01-01
333 Crockett, David K.Utility of gene-specific algorithms for predicting pathogenicity of uncertain gene variantsThe rapid advance of gene sequencing technologies has produced an unprecedented rate of discovery for genome variation in humans. A growing numbered of authoritative clinical repositories archive gene variants and disease phenotype, yet there are currently many more gene variants that lack clear ann...2012
334 Kestle, John R. W.Abdominal bindersSklar and colleagues2 describe their experience managing "over-shunting headaches" with an abdominal binder. Seventy children with over-shunting headaches complied with application of a binder for about 1 month. In 61 patients (87%), the headaches "greatly improved or went away." This headache relie...2012-01-01
335 Warner, Homer R.Clinical Data Collection With a PurposeBiomedical Informatics1968
336 Warner, Homer R.Computer Assisted Teaching of Cardiac ArrhythmiasBiomedical Informatics1968
337 Capecchi, Mario R.Homologous recombination between coinjected DNA sequences peaks in early to mid-S phase.We have examined the effect of cell cycle position on homologous recombination between plasmid molecules coinjected into synchronized rat fibroblasts. Recombination activity was found to be low in G1 and to rise 10- to 15-fold, peaking in early to mid-S phase.Cell Line; Kinetics; Plasmids1986-06
338 Couldwell, William T.Initial experience related to the use of the Cosman-Roberts-Wells stereotactic instrumentInitial experience with a new arc-radius design of stereotactic frame that interfaced with the existing components of the Brown-Roberts-Wells instrument is reported. Over a 6-month period, 32 procedures were performed on 23 males and nine female patients (mean age 32 years); these included 27 ster...Image-directed stereotaxis; Stereotactic instrument; Cosman-Roberts-Wells stereotaxy1990
339 Warner, Judith E. A.Intermittent reversal of Complete Ptosis-EganWarnerCASE REPORT: Ptosis secondary to dense oculomotor pareses generally improves over several months, but intermittent elevation of the eyelid has not been reported. The Author's describe two patients who demonstrated intermittent involuntary monocular eyelid elevation in an eye with complete ptosis cau...Eyelids; Ophthalmoplegia; Intraoperative Complications2006
340 Gardner, Reed M.Pressure to Perform: Is Cardiac Output Estimation from Arterial Waveforms Good Enough for Routine Use?Biomedical Informatics2009
341 Couldwell, William T.; MacDonald, Joel D.Revision of vagal nerve stimulator electrodes: technical approachPurpose To demonstrate the feasibility of complete removal of the vagal nerve stimulator electrode using microsurgical technique. Methods Operative databases at the University of Utah (1995 through 2002), Westchester Medical Center (1995 through 2001), and University of Arizona Health Sciences Ce...Vagal nerve stimulation; Helical electrode; Electrode revision2004
342 Camp, Nicola J.Survey of excess familiality in prostate cancerProstate cancer (PCa) is the most commonly diagnosed cancer among men, and has long been recognized to occur in familial clusters. However, identification of genes predisposing individuals to prostate cancer has been difficult. Putative PCa predisposition loci identified by genetic linkage have been...Prostate cancer; Utah Population Database; Linkage analysis; Familial compotent; Excess familiality; Trapeze Interactive Poster2009
343 Poulter, Charles DaleTetartohedral twinning in IDI-2 from Thermus thermophilus: crystallization under anaerobic conditionsType-2 isopentenyl diphosphate isomerase (IDI-2) is a key flavoprotein involved in the biosynthesis of isoprenoids. Since fully reduced flavin mononucleotide (FMNH2) is needed for activity, it was decided to crystallize the enzyme under anaerobic conditions in order to understand how this reduced co...2014-01-01
344 Couldwell, William T.; Gottfried, Oren N.Too many? Too few. New study reveals current trends in U. S. neurosurgical workforceRemarkable changes in the neurosurgical specialty have taken place in the past 15 years. While advances in basic science have occurred and new technologies and therapies have proliferated, other, less propitious factors-such as the promises (some might say false promises) and hopes of managed care-h...2003-01-01
345 Warner, Homer R.A Decision Support Technology ClearinghouseBiomedical Informatics1988
346 Warner, Homer R.Computerized Medication Monitoring SystemBiomedical Informatics1976
347 Couldwell, William T.; Apfelbaum, Ronald I.Decompression of cavernous sinus meningioma for preservation and improvement of cranial nerve functionMeningiomas are the most common tumors affecting the cavernous sinus (CS). Despite advances in microsurgery and radiosurgery, treatment of CS meningiomas remains difficult and controversial. As in cases of other meningiomas, the goal of treatment for CS meningioma is long-term growth control and pre...2006-07
348 Couldwell, William T.Photophobia in a blind patient: an alternate visual pathwayPhotophobia is a common neurological and ophthalmological symptom that has been associated with a growing number of neurosurgical conditions, especially compressive lesions. The exact signaling pathways and neurophysiological features of the disorder are not well understood; however, data from mult...2006-11
349 Digre, Kathleen B.; Couldwell, William T.; Amini, AminPhotophobia in a blind patient: An alternate visual pathway. Case report.Photophobia is a common neurological and ophthalmological symptom that has been associated with a growing number of neurosurgical conditions, especially compressive lesions. The exact signaling pathways and neurophysiological features of the disorder are not well understood; however, data from multi...Photophobia, Blindness, Signaling Pathway, Pretectal Nuclei, Trigeminal Pathway2006-12-14
350 Varner, Michael W.; Esplin, Michael S.Progression of pulmonary arteriovenous malformation during pregnancy: case report and review of the literature.Arteriovenous Malformations; Pulmonary Artery; Pregnancy Complications; Pulmonary Veins; Pulmonary Artery1997-04
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