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CreatorTitleDescriptionSubjectDate
276 Dailey, Andrew T.Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 2: Assessment of functional outcome following lumbar fusionAssessment of functional patient-reported outcome following lumbar spinal fusion continues to be essential for comparing the effectiveness of different treatments for patients presenting with degenerative disease of the lumbar spine. When assessing functional outcome in patients being treated with l...2014-01-01
277 Couldwell, William T.Pituitary apoplexy in the magnetic resonance imaging era: clinical significance of sphenoid sinus mucosal thickeningObject. The authors report their experience with pituitary apoplexy and evaluate the clinical significance of sphenoid sinus mucosal thickening found on magnetic resonance (MR) imaging. Methods. The cases of 28 patients (19 males and nine females) with pituitary apoplexy were reviewed retrospectiv...2006-06
278 Schmidt, Meic H.; Apfelbaum, Ronald I.Cervical spinal metastasis: anterior reconstruction and stabilization techniques after tumor resectionObject. In a review of the literature, the authors provide an overview of various techniques that have evolved for reconstruction and stabilization after resection for metastatic disease in the subaxial cervical spine. Methods. Reconstruction and stabilization of the cervical spine after vertebral...Cervical spine reconstruction; Metastasis; Spine tumor; Corpectomy; Stabilization technique; Vertebral body2003
279 Lopansri, Bert; Stoddard, Gregory J.; Hobbs, Maurine R.; Granger, Donald LeeElevated plasma phenylalanine in severe malaria and implications for pathophysiology of neurological complications.Cerebral malaria is associated with decreased production of nitric oxide and decreased levels of its precursor, l-arginine. Abnormal amino acid metabolism may thus be an important factor in malaria pathogenesis. We sought to determine if other amino acid abnormalities are associated with disease sev...Dystonia; Phenylalanine Hydroxylase; Tyrosine2006-06-01
280 Couldwell, William T.; Chin, Steven S.Extranodal NK/T-cell lymphoma presenting as a pituitary massExtranodal NK/T-cell lymphomas are uncommon neoplasms that are highly aggressive and show a strong association with Epstein-Barr virus. They most commonly affect the nasal cavity and paranasal sinuses; manifestation as a primary pituitary tumor has never been described. The authors report a case of ...2007-09
281 Couldwell, William T.Inhibition of cellular growth and induction of apoptosis in pituitary adenoma cell lines by the protein kinase C inhibitor hypericin: potential therapeutic applicationProtein kinase C (PKC) is an enzyme involved in the regulation of cellular growth, proliferation, and differentiation in a number of tissues including the anterior pituitary, in which it is also believed to play a role in hormone secretion. Protein kinase C activity and expression have been found to...Apoptosis; Hypericin; Pituitary adenoma; Protein kinase C1996
282 Bernstein, Paul S.; Gellermann, WernerRaman detection of macular carotenoid pigments in intact human retinaPURPOSE: To develop and test a novel noninvasive optical technique suitable for the objective measurement of macular carotenoid levels in human retina. METHODS: A resonance Raman scattering apparatus was constructed to measure carotenoid levels in flat-mounted human retinas and eyecups and in experi...Rana pipiens; Spectrum Analysis, Raman; Xanthophylls1998
283 Couldwell, William T.Astrocytoma cell lineTO THE EDITOR: It has long been established clinically that patients with neurofibromatosis Type 1 (NF1) have an increased susceptibility to develop many central and peripheral tumors. The nature of the genetic alterations underlying NF1 have recently begun to be characterized. It has been demo...2001
284 Gardner, Reed M.Continuous Cardiac Output: How Accurate and How Timely? (Editorial)Biomedical Informatics1988
285 Capecchi, Mario R.Gene targeting: tapping the cellular telephone.Gene targeting means that we now have the potential to generate mice of virtually any desired genotype. In the first instance, standards recombinant DNA technology is used to alter a cloned DNA sequence of a chosen locus; the modified potent stem cell derived from a mouse embryo, and homologous reco...Animals; Blotting, Southern; Bone and Bones; Gene Targeting; Genotype; Immunochemistry; In Situ Hybridization; Mice1990-03-08
286 Camp, Nicola J.Genetic susceptibility of prostate cancer: genome-wide screen of "non-aggressive" diseaseResearch has consistently shown that genetics plays a critical role in prostate cancer (CaP) development, but the identification of CaP genes has proven to be very difficult. Hereditary prostate cancer is a complex disease believed to involve numerous genes and variable penetrance. It has been propo...CaP genes; Prostate cancer; Non-aggressive; Utah Population Database; Trapeze Interactive Poster2009
287 Warner, Homer R.The HELP System as a Tool for Monitoring Physician Prescribing PatternsBiomedical Informatics1980
288 Couldwell, William T.Medical and surgical management of microprolactinomaA recent report by Colao et al. [1] indicates that a significant proportion of patients harboring prolactinomas treated with cabergoline will have persistence of remission of hyperprolactinemia following withdrawal of the drug. The prolactin and tumor control rates in the study suggest that medical ...Microprolactinoma; Prolactinoma; Cabergolene2004
289 Warner, Homer R.The Tradeoffs Between Timesharing and Dedicated Computers in a Medical SettingBiomedical Informatics1983
290 O'Rourke, Dennis H.Ascertainment bias for non-twin relatives in twin proband studiesWhen families are ascertained through affected twins, as for example when twin probands are selected from a registry and their non-twin relatives studied, a correction for ascertainment bias is needed. It is shown that probandwise counting (where relatives of doubly ascertained twin pairs are counte...Genetic; Transmission; Models1982
291 Capecchi, Mario R.Choose your target.The technology of modifying endogenous genes has recently been extended from mice to Drosophila and sheep. Concurrently, genomic sequencing is uncovering thousands of previously uncharacterized genes. Armed with today's technologies, what are our best options for delineating the functions of these n...Animals; Mice; Sheep2000-09-13
292 Mitchell, Joyce A.Evidence-based retrieval in evidence-based medicineObjective: Clinical decisions based on a meta-analysis that is based on an ineffective retrieval strategy may have serious negative consequences for patients. The study objective was to investigate the extent to which meta-analyses report proof of their retrieval strategies' effectiveness. Methods: ...2004-01-01
293 Warner, Homer R.KESS: Knowledge Engineering Support SystemBiomedical Informatics1987
294 Kestle, John R. W.; Walker, Marion L.Noncommunicating spinal extradural arachnoid cyst causing spinal cord compression in a childExtradural arachnoid cysts in the spine are relatively uncommon causes of spinal cord compression in the pediatric population that are thought to arise from congenital defects in the dura mater. Most reports describe such cysts communicating with the intrathecal subarachnoid space through a small de...2006
295 Buchi, Karen F.; Varner, Michael W.Prevalence of substance abuse among pregnant women in Utah.OBJECTIVE: To determine the rate of substance use among Utah's pregnant women, who are primarily white and middle class, for comparison to rates reported in studies of inner-city populations. METHODS: Urine specimens and demographic data were obtained anonymously from women who delivered infants at ...Substance Abuse; Pregnancy; Utah/epidemiology1993-02
296 Couldwell, William T.Radiographic features of tumefactive giant cavernous angiomasGiant cavernous angiomas (GCAs) are very rare, and imaging features of GCAs can be very different from those of typical cavernous angiomas (CAs), making them a diagnostic challenge. The purpose of the study was to evaluate the radiographic features of GCAs, with an emphasis on the differentiating fe...Cavernous angiomas; Cavernous malformations; Tumefactive2008
297 Sample, SusanShattering stereotypes: aging adults aren't naturally unhappyHealthy older adults ramain engaged and interested in life. Just because they're aging doesn't mean they lose interest in life. "In this culture, we have a perception of what it's like to grow old: life isn't a whole lot of fun" We have an image of older adults whose faces are lined with fatigue as ...Aging Adults; Depression; Geriatrics1998-12
298 Dailey, Andrew T.Subaxial cervical spine trauma classification: the subaxial injury classification system and case examplesObject. The authors review a novel subaxial cervical trauma classification system and demonstrate its application through a series of cervical trauma cases. Methods. The Spine Trauma Study Group collaborated to create the Subaxial Injury Classification (SLIC) and Severity score. The SLIC system is...Cervical spine trauma; Injury severity score; Spinal cord injury; Subaxial Injury Classification; SLIC; Discoligamentous integrity; Neurological status2008
299 Dailey, Andrew T.Thoracolumbar spine trauma classification: the Thoracolumbar Injury Classification and Severity Score system and case examplesObject. The aim of this study was to review the Thoracolumbar Injury Classification and Severity Score (TLICS) and to demonstrate its application through a series of spine trauma cases. Methods. The Spine Trauma Study Group collaborated to create and report the TLICS system. The TLICS system is re...Thoracolumbar spine trauma; Classification; Thoracolumbar injury; TLICS; Spine Trauma Study Group; Thoracolumbar Injury Classification and Severity Score2009
300 Couldwell, William T.Combined transmastoid retro- and infralabyrinthine transjugular transcondylar transtubercular high cervical approach for resection of glomus jugulare tumorsCOMPLEX TUMORS OF the glomus jugulare present a surgical challenge because of their difficult location, extreme vascularity, and involvement with multiple cranial nerves. Modern microneurosurgical and cranial base techniques have enabled safe total removal of these complicated tumors. We describe a ...Cranial base approach; Surgical approach; Glomus jugulare tumor; Jugular foramen exposure; Microsurgical anatomy2006
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