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1 Gerig, GuidoProbabilistic white matter fiber tracking using, particle filtering and von mises-fisher samplingStandard particle filtering technique have previously been applied to the problem of fiber tracking by Brun et al. (2002) and Bjornemo et al. (2002). However, these previous attempts have not utilised the full power of the technique, and as a result the fiber paths were tracked in a goal directed wa...Diffusion tensor MRI; Tractography; Probabilistic fiber tracking; Particle filtering; von Mises-Fisher sampling2009-01-01
2 Gerig, GuidoPrenatal isolated mild ventriculomegaly is associated with persistent ventricle enlargement at ages 1 and 2Background-Enlargement of the lateral ventricles is thought to originate from abnormal prenatal brain development and is associated with neurodevelopmental disorders. Fetal isolated mild ventriculomegaly (MVM) is associated with enlargement of lateral ventricle volumes in the neonatal period and dev...Magnetic resonance imaging; Ultrasound; Gray matter; White matter; Cognitive development2012-01-01
3 Gerig, GuidoParticle based shape regression of open surfaces with applications to developmental neuroimagingShape regression promises to be an important tool to study the relationship between anatomy and underlying clinical or biological parameters, such as age. In this paper we propose a new method to building shape models that incorporates regression analysis in the process of optimizing correspondences...2009-01-01
4 Gerig, GuidoGroup analysis of DTI fiber tract statistics with application to neurodevelopmentDiffusion tensor imaging (DTI) provides a unique source of information about the underlying tissue structure of brain white matter in vivo including both the geometry of major fiber bundles as well as quantitative information about tissue properties represented by derived tensor measures. This paper...Diffusion tensor imaging; Registration; Tract modeling; Neurodevelopment; Statistical modeling2009-01-01
5 Gerig, GuidoSpatiotemporal atlas estimation for developmental delay detection in longitudinal datasetsWe propose a new methodology to analyze the anatomical variability of a set of longitudinal data (population scanned at several ages). This method accounts not only for the usual 3D anatomical variability (geometry of structures), but also for possible changes in the dynamics of evolution of the str...2009-01-01
6 Gerig, GuidoNeuroimaging of structural pathology and connectomics in traumatic brain injury: toward personalized outcome predictionRecent contributions to the body of knowledge on traumatic brain injury (TBI) favor the view that multimodal neuroimaging using structural and functionalmagnetic resonance imaging (MRI and fMRI, respectively) as well as diffusion tensor imaging (DTI) has excellent potential to identify novel biomark...Trauma; Neuroimaging; MRI/fMRI; Diffusion tensor; Outcome measures2012-01-01
7 Gerig, GuidoSimulation of brain tumors in MR images for evaluation of segmentation efficacy.Obtaining validation data and comparison metrics for segmentation of magnetic resonance images (MRI) are difficult tasks due to the lack of reliable ground truth. This problem is even more evident for images presenting pathology, which can both alter tissue appearance through infiltration and cause ...Brain MRI; Segmentation validation; Tumor simulation; Simulation of tumor infiltration; Diffusion tensor imaging; Ground truth; Gold standard2009-01-01
8 Yanowitz, Frank G.Alan E. Lindsay ECG Learning Center in CyberspaceAn interactive ECG tutorial representing an introduction to clinical electrocardiography.Electrocardiography1996-09-01
9 Gerig, GuidoReduced interhemispheric connectivity in schizophrenia- tractography based segmentation of the corpus callosumBackground-A reduction in interhemispheric connectivity is thought to contribute to the etiology of schizophrenia. Diffusion Tensor Imaging (DTI) measures the diffusion of water and can be used to describe the integrity of the corpus callosum white matter tracts, thereby providing information concer...2008-01-01
10 North American Neuro-Ophthalmology Society (NANOS)Neuro-ophthalmology virtual education library (NOVEL)An extensive, accessible collection of high quality digital materials to cover all of neuro-ophthalmology for use by educators and students world wide.Neuro-Ophthalmology; NOVEL; Neuro-Ophthalmology Virtual Education Library2005-08-11
11 Arlitsch, KenningCollaboration and partnerships: opportunities aboundPowerPoint presentation describing some of the digital collection building partnerships of the University of Utah. Major covered projects include the Utah Digital Newspapers Program, Mountain West Digital Library, Western Waters Digital Library, and the Utah Artists Project, among others.Digital collections; Electronic libraries; Cooperative collection building2006-01-22
12 Dennis, Sharon E.; Uijtdehaage, Sebastian; Candler, C.Health Education Assets Library (HEAL)The Health Education Assets Library (HEAL) is a digital library that provides freely accessible digital teaching resources of the highest quality that meet the needs of today's health sciences educators and learners.HEAL; Health Education Assets Library2000
13 Arlitsch, KenningFuture leaders of research libraries: what are they thinking?Summarizes the initial findings of survey research conducted with 175 future library leaders. Respondents were asked whether they are satisfied with their organizational culture and management, whether organizational culture limits thier effectiveness, and whether respondents are consideringleaving...Future leaders2009-04-06
14 Hawkes, KristenA reappraisal of grandmothering and natural selectionKachel et al. [1] conclude from simulations of their agent-based model that fitness benefits from helpful grandmothers do not select for increased longevity. We studied their assumptions and model, ran further simulations and found flaws that are fatal to their test. Here, we explain four problems a...2011-01-01
15 Hawkes, KristenEvaluating grandmother effectsWomen who have outlived child-bearing have long been described as post-reproductive. But contributions they make to the survival or fertility of their descendants enhance the reproduction of their genes. Consequently natural selection affects this characteristic stage of human life history. Grandmot...Human life history; Historical demography; Human longevity2009-01-01
16 Hawkes, KristenIncreased longevity evolves from grandmotheringPostmenopausal longevity may have evolved in our lineage when ancestral grandmothers subsidized their daughters' fertility by provisioning grandchildren, but the verbal hypothesis has lacked mathematical support until now. Here, we present a formal simulation in which life spans similar to those of ...Human evolution; Life history; Sexual conflict2012-01-01
17 Gerig, GuidoUnbiased atlas formation via large deformations metric mappingThe construction of population atlases is a key issue in medical image analysis, and particularly in brain mapping. Large sets of images are mapped into a common coordinate system to study intrapopulation variability and inter-population differences, to provide voxelwise mapping of functional sites,...Computational anatomy; Brain atlases; Image metric space2005-01-01
18 Gerig, GuidoNetwork inefficiencies in autism spectrum disorder at 24 monthsAutism spectrum disorder (ASD) is a developmental disorder defined by behavioral symptoms that emerge during the first years of life. Associated with these symptoms are differences in the structure of a wide array of brain regions, and in the connectivity between these regions. However, the use of c...2014-01-01
19 Gerig, GuidoUser-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliabilityActive contour segmentation and its robust implementation using level set methods are well-established theoretical approaches that have been studied thoroughly in the image analysis literature. Despite the existence of these powerful segmentation methods, the needs of clinical research continue to b...Computational anatomy; Image segmentation; Caudate nucleus; 3D active contour models; Open source software; Validation; Anatomical objects2006-01-01
20 Gerig, GuidoAbnormal brain synchrony in down syndromeDown Syndrome is the most common genetic cause for intellectual disability, yet the pathophysiology of cognitive impairment in Down Syndrome is unknown. We compared fMRI scans of 15 individuals with Down Syndrome to 14 typically developing control subjects while they viewed 50 min of cartoon video c...2013-01-01
21 Gerig, GuidoProbabilistic fiber tracking using particle filteringThis paper presents a novel and fast probabilistic method for white matter fiber tracking from diffusion weighted MRI (DWI). We formulate fiber tracking on a nonlinear state space model which is able to capture both smoothness regularity of fibers and uncertainties of the local fiber orientations du...2007-01-01
22 Gerig, GuidoFrontolimbic neural circuitry at 6 months predicts individual differences in joint attention at 9 monthsElucidating the neural basis of joint attention in infancy promises to yield important insights into the development of language and social cognition, and directly informs developmental models of autism. We describe a new method for evaluating responding to joint attention performance in infancy tha...Joint attention; DTI; Amygdala; Uncinate fasciculus; Infancy; Development2013-01-01
23 Gerig, GuidoAsymmetrical ventricular enlargement in Parkinsons DiseaseBackground-A recent case report suggested the presence of asymmetrical lateral ventricular enlargement associated with motor asymmetry in Parkinson's disease (PD). The current study explored these associations further. Methods-Magnetic resonance imaging (3T) scans were obtained on 17 PD and 15 healt...Structural magnetic resonance imaging; Semi-automatic segmentation; Lateral ventricular volume; Motor asymmetry; Parkinson's disease2007-01-01
24 Gerig, GuidoFiber tract-oriented statistics for quantitative diffusion tensor MRI analysisDiffusion tensor imaging (DTI) has become the major modality to study properties of white matter and the geometry of fiber tracts of the human brain. Clinical studies mostly focus on regional statistics of fractional anisotropy (FA) and mean diffusivity (MD) derived from tensors. Existing analysis t...Diffusion tensor interpolation, Diffusion tensor statistics, DTI analysis, Fiber tract modeling2006-01-01
25 Gerig, GuidoVessel tortuosity and brain tumor malignancy: a blinded studyRationale-Malignancy provokes regional changes to vessel shape. Characteristic vessel tortuosity abnormalities appear early during tumor development, affect initially healthy vessels, spread beyond the confines of tumor margins, and do not simply mirror tissue perfusion. The ability to detect and qu...Computer; Cancer; Blood vessels; Tortuosity; MRA; Brain tumor2005-01-01
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