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1 Capecchi, Mario R.Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures.Hox genes encode transcription factors that are used to regionalize the mammalian embryo. Analysis of mice carrying targeted mutations in individual and multiple Hox genes is beginning to reveal a complex network of interactions among these closely related genes which is responsible for directing th...Abnormalities, Multiple; Gene Targeting; Glossopharyngeal Nerve; Mice, Knockout; Morphogenesis1997-12-15
2 Fuhrmann, Sabine; Zhang, Jianmin; Vetter, Monica L.Investigation of Frizzled-5 during embryonic neural development in mouseCellular and tissue--tissue interactions regulate development of the central nervous system (CNS) and a paramount question is what is the nature of the signals involved in these interactions. The vertebrate eye represents an excellent and challenging CNS model because it contains multiple cell and ...Mouse; Eye; Optic cup; Morphogenesis; Retina; Lens; Wnt; Frizzled; Pituitary2008
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