Honors Theses Open Access
 
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26 Dean, EmmaThe Effects of maternal resilience on newborn neurobehavioral outcomesThere is growing evidence that exposure to prenatal maternal stress may adversely affect fetal neurodevelopment by altering the fetal environment. In this study, we investigated whether maternal resilience can act as a moderator of the negative effects of maternal stress on newborn neurobehavioral o...2020
27 Vandamme, Elise-MarieThe role of dehydroepiandrosterone in the pathophysiology of Tourette syndrome: preclinical studiesTourette syndrome (TS) is a neurodevelopmental condition with a marked male predominance (M: F= 3:1), characterized by multiple motor and one or more vocal tics for more than one year and beginning before the age of 18 (Robertson, 2019). Our understanding of TS pathophysiology remains limited; as a ...2022
28 Enquist, AnnekeDiscovery of platinum (II) and azulene derivative cocrystals with fluorinated cyanoaromaticsPentacyano-trifluoromethyl benzene was synthesized using a novel technique. Before isolation, it was noted that plate like crystals had formed leading to study regarding the ability of acetic acid to co-crystallize with pentacyanotrifluoromethyl benzene. The crystal structure of acetic acid with pen...2024
29 Lietzke, StephanieRemoval of endotoxins from recombinant antithrombinEndotoxins (also known as lipopolysaccharides or ETs) are a pyrogenic byproduct of the breakdown of gram-negative bacterial cell-walls, such as E. coli. They cause fever and septic shock in humans, and are therefore highly regulated by the FDA and USP. ETs are a common contaminant in recombinant pr...Endotoxins - Research; Antithrombins - Therapeutic use; Sheep as laboratory animals - Research; endotoxin removal; Angiogenesis2016-04
30 Sperber, Alexander M.A novel approach to differentiating cardiac fibroblasts from induced pluripotent stem cellsHeart disease remains the leading cause of death in the United States, and such disease is caused by electrical, chemical, or biomechanical imbalances in the heart. The two most abundant cells comprising the heart that are responsible for these functions are cardiomyocytes and cardiac fibroblasts. I...2022
31 Estrada, JohannaBCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Philadelphia cromosome-positive leukemiaCML 1s caused by a random reciprocal translocation that joins the ABL1 gene on chromosome 9, with the BCR gene on chromosome 22. The result is the formation of the oncogenic BCR-ABL1 gene. This derivative chromosome is widely known as the Philadelphia Chromosome (Ph+), and it encodes a deregulated, ...Leukemia -- Genetic aspects -- Research Leukemia -- Treatment -- Research2014-04
32 Kiel, DrewHow branding influences our willingness to pay for necessity productsThough marketing has existed in one manner or another for the duration of human history, the field has only seen strong development since the beginning of the 20th century. Marketing is now an inescapable part of everyday life and companies across every industry advertise of to us as potential custo...2021
33 Som, SaritaVirus-like weapons used for competition in wild plant populationsPlant diseases caused by bacterial pathogens pose significant economic challenges globally, necessitating the exploration of alternative methods for controlling bacterial infections in plants. Tailocins, virus-like weapons produced by bacteria, have emerged as potent antibacterial agents and hold po...2023
34 Hodgson, Keeton R.Accelerating DNA Sequence AlignmentPrecision medicine can provide breakthroughs in current medical technology and treatment. The ability to prescribe a speci#12;c cure to a speci#12;c disease for a spe- ci#12;c person can greatly reduce the cost of medical treatments, reduce mistakes in the medical #12;eld, and increase the e#11;ecti...2018
35 Ward, Bridget E.Functionalizing a hemagglutinin epitope tag for induced mitochondrial protein degradation in saccharomyces cerevisiaeMitochondria are organelles known for their role in many critical cellular processes including the production of metabolic energy in eukaryotic cells. In order to produce this energy, mitochondria continually transport metabolites across the impermeable mitochondrial inner membrane. The transport of...2022
36 Pace, Eliza JaneHigh School curriculum on social media and mental wellbeing: combating the negative effects through education and applicationOver the past ten years, there has been a significant rise of depression and suicide rates in adolescents. These rates coincide almost exactly with the rise in smartphone use and the development of social media. Evidence of multiple studies over the last twenty years suggests that social media plays...2021
37 Bracken, KallieDefining learning: mystifying machine learning as a powerful tool in a data-driven worldUntil recently, the driving paradigm in software engineering has been to design applications for a predefined set of tasks. This approach, however, is quickly being dwarfed by data-driven applications which are designed to use knowledge and understanding to decide how they can best fulfill use...Machine learning - Case studies; Machine learning - Study and Teaching; Machine Learning - Technique2016-04
38 Halberg, CharlesOn causality in machine learningAlthough the studies of causal inference and machine learning arose independently, there are emerging intersections which are proving fruitful for both fields. One of the major modern challenges in AI is to develop robust, generalizable models which can perform across a number of different tasks wit...2022
39 Russell, SloanChanging brand perception: Changing university students' attitude toward a company and enabling a talented recruiting poolStudents often participate in internships to gain real-world experience before entering the workforce. This proves beneficial to students, allowing them to apply the skills they learned via higher education and develop problem-solving abilities, while employers find internships allow them to recruit...Business education (Internship); Marketing2015-04
40 Bacon, Brandon ToddHealthcare culture and the innovation climate of the Salt Lake ValleyHealthcare innovation has become an important issue over the past ten years in the health industry. However, consistently fostering the development and integration of new ideas and technologies into healthcare often runs counter to long held organizational norms and values. Many healthcare systems b...Medical care - Utah - Salt Lake Valley; Organization change - Utah - Salt Lake City2013-05
41 Lotz, Mahalia G.Victim/Survivor Notifications on Utah Sexual Assault Kit Re-Traumatization & Engagement in the Criminal Legal SystemThis paper provides context for the creation, discovery, and aftermath of the multitude of unsubmitted sexual assault kits. It continues by describing the efforts of the Utah Sexual Assault Kit Initiative (SAKI) group to address the issues created by the unsubmitted kits. This paper specifically exa...2019
42 Leibold, Katherine I.The Electability of Atheists in the United StatesAtheists are severely underrepresented in United States public offices. This underrepresentation is obvious when evaluating the religious affiliation of our elected officials in Congress in contrast to the religious affiliations of the general public. The underrepresentation of atheists in Congress ...2018
43 Arave, Rowan A.AKT1 activation promotes the development of melanoma metastasisMetastases are the major cause of melanoma-related mortality. Previous studies implicating aberrant AKT (or protein kinase B) signaling in human melanoma metastases led to the evaluation of the effect of activated AKT1 expression in non-metastatic BRAFV600E/cyclin dependent kinase inhibitor 2a nu...Melanoma - Genetics - Research; Metastasis - Genetics - Research; Biochemistry; Genetics2015-12
44 Uong, AmberA female's first year of college stress, mental health, and alcoholTransitioning to college marks a critical period of change in a student's life. Students become exposed to new environments that require adaptation. College courses come with academic expectations that are typically higher than those experienced in high school. This honors thesis will review academi...2018
45 Tarboton, PaisleyCharacterization of Apoptosis and Inhibitory Neurons in Cortical Organoids Generated from Human Induced Pluripotent Stem Cells.Modeling human brain diseases in a laboratory setting is critical to understanding the underlying pathology and developing new treatments for patients. Organoids are 3D tissue cultures that provide a promising way to model human brain development in vitro and have been used previously to gain novel ...2018
46 Pecchia-Beekum, AnnikaWho's got the pants?: breeching distinctions of power in restoration theatre and pre-hays code hollywoodIn the 1660s, after the Restoration of Charles II to the throne, female performers acted on stage for the first time, leading to increasingly sexualized female characters and investigations into gender roles. "Breeches" roles, where women cross-dressed, became progressively more popular, with actres...Cross-dressing - History; Cross-dressing in art; Gender & sexualities in minds & cultures2012-05
47 Gonzalez, Marcos DavidAn Analysis of the Court of Arbitration system: Status & Power Through the Lens of LaugtherLaughter is a nonverbal communication that demonstrates status and power across contexts such as hospital wards, fraternities, and even the United States Supreme Court. While it may be humorous in nature, the implications of laughter as a symbol that gathers perceived status, a mediator of social hi...2020
48 Jones, AdamGive me a Viking Funeral: Fighting Ideology with Ideology in the Dystopia of V for VendettaA photograph of the Antarctic landscape is, for many, the only way through which they understand the continent's existence. Most have never travelled there and for them, photography and other representations of its geography are the only proof that it actually exists. This photograph then becomes th...2015
49 Shapiro, DarienActivation of transient receptor potential ankyrin-1 by wood smoke particulate materialExposure to wood smoke particulate matter (WSPM) has been linked to exacerbation of pre-existing respiratory conditions such as asthma, development of chronic obstructive pulmonary disease (COPD), and premature deaths. While it is clear that WSPM exposure is hazardous to human health, the molecular ...Smoke - Physiological effect2012-05
50 Vlasic, KajsaStorytelling and the patient experience: Narratives of breast cancer survivorsThrough my young life, I have been fortunate enough to be surrounded and supported by a loving and extended family of mothers. Although I will only have one biological mom, I have collected other women as role models and confidantes who have guided and spoken words of encouragement through my most i...Breast cancer patients' writings2014-12
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