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TitleCreatorDescriptionSubject
1 Alcoholic Cerebellar DegenerationShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Alcoholic Cerebellar Degeneration; Dysmetria; Gait Ataxia; Gaze Evoked Horizontal Nystagmus; Horizontal Gaze Evoked Nystagmus; Horizontal Saccadic Dysmetria; Horizontal Saccadic Hypermetria; Saccadic Pursuit; Square Wave Jerks
2 Alcoholic Cerebellar DegenerationShirley H. Wray, MD, PhD, FRCPThe patient is a 72 year old woman who presented with a 4 year history of progressive difficulty with balance, frequent falls and unsteadiness walking. She required a cane to steady herself. Past History: Significant for alcohol abuse. In 1980, she came to Boston for a second opinion and was seen in...Square Wave Jerks; Dysmetria; Horizontal Saccadic Hypermetria; Horizontal Gaze Evoked Nystagmus; Saccadic Pursuit; Gait Ataxia; Alcoholic Cerebellar Degeneration; Gaze Evoked Horizontal Nystagmus; Horizontal Saccadic Dysmetria; Alcohol
3 Bilateral Internuclear OphthalmoplegiaShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Abducting Nystagmus; Bilateral Internuclear Ophthalmoplegia; Botulinum Toxin Therapy; Gaze Evoked Upbeat Nystagmus; Horizontal Pendular Nystagmus; Lid Nystagmus; Multiple Sclerosis; Pendular Horizontal Oscillations; Upbeat Nystagmus
4 Bilateral Internuclear OphthalmoplegiaShirley H. Wray, MD, PhD, FRCPThis patient was seen at the Yale Eye Center at the age of 37. She had a long history of multiple sclerosis. At age 22, she had an acute attack of optic neuritis in the left eye which recovered fully within three weeks. Some months later she had a recurrent episode in the same eye, which also recove...Bilateral Internuclear Ophthalmoplegia; Pendular Horizontal Oscillations; Lid Nystagmus; Upbeat Nystagmus; Botulinum Toxin Therapy; Multiple Sclerosis; Horizontal Pendular Nystagmus; Gaze Evoked Upbeat Nystagmus; Abducting Nystagmus
5 Brain MRI in Multiple SclerosisAnne G. Osborn, MDSlideshow describing condition.Abducting Nystagmus; Bilateral Internuclear Ophthalmoplegia; Botulinum Toxin Therapy; Gaze Evoked Downbeat Nystagmus; Horizontal Pendular Nystagmus; Horizontal Saccadic Dysmetria; Lid Nystagmus; Multiple Sclerosis; Normal Convergence; Oscillopsia; Pendular Horizontal Oscillations; Saccadic Dysmetri...
6 Brain MRI in Multiple Sclerosis (Guest Lecture)Anne G. Osborn, MDThe patient is a 25 year old woman who was in excellent health until 4 days prior to admission when she noted blurred vision and horizontal double vision on lateral gaze to right and left. Past History: Negative for strabismus as a child. No previous episodes of transient neurological symptoms. Fami...Bilateral Internuclear Ophthalmoplegia; Abducting Nystagmus; Normal Convergence; Gaze Evoked Upbeat Nystagmus; Gaze Evoked Downbeat Nystagmus; Saccadic Dysmetria; Multiple Sclerosis; Horizontal Saccadic Dysmetria
7 Brainstem Cavernous AngiomaShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Bilateral Horizontal Gaze Palsy Hemorrhage; Bilateral Lid Nystagmus; Cavernous Angioma; Hiccup; Horizontal Gaze Evoked Nystagmus; Lid Nystagmus; Medulla Hemorrhage; Medullary Hemorrhage; Primary Position Upbeat Nystagmus; Upbeat Nystagmus
8 Brainstem Cavernous AngiomaShirley H. Wray, MD, PhD, FRCPThe patient is a 50 year old woman who presented in November 1977 with a transient facial droop, nystagmus, diplopia, dysarthria and vertigo. She was admitted to New England Tufts Medical Center and had an extensive workup including an electroencephalogram, first generation CT brain scan, angiogram ...Upbeat Nystagmus; Lid Nystagmus; Horizontal Gaze Evoked Nystagmus; Hiccup; Medullary Hemorrhage; Cavernous Angioma; Bilateral Lid Nystagmus; Bilateral Horizontal Gaze Palsy Hemorrhage; Primary Position Upbeat Nystagmus; Medulla Hemorrhage; Medulla
9 Cavernous AngiomaShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Cavernous Angioma; Convergence Normal; Facial Palsy; Fisher's One-and-a-Half Syndrome; Pendular Vertical Oscillations; Pontine Hemorrhage; Unilateral Gaze Palsy Hemorrhage; Unilateral Horizontal Gaze Palsy; Unilateral Internuclear Ophthalmoplegia; Upbeat Nystagmus on Upgaze
10 Cavernous AngiomaShirley H. Wray, MD, PhD, FRCPThe patient is a 19 year old sophomore who presented in 1983 with numbness of the left hand, involving initially just the fingers, and numbness and weakness of the right side of the face. He described the numbness in his hand as if it was "intensely asleep". The facial numbness involved the perioral...Unilateral Internuclear Ophthalmoplegia; Unilateral Horizontal Gaze Palsy; Upbeat Nystagmus on Upgaze; Convergence Normal; Pendular Vertical Oscillations; Facial Palsy; Fisher's One-and-a-Half Syndrome; Pontine Hemorrhage; Cavernous Angioma; Unilateral Gaze Palsy Hemorrhage; Abducting Nystagmus; Fac...
11 Cavernous Sinus MeningiomaShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Abducting Nystagmus; Cavernous Angioma; Convergence Normal; Facial Palsy; Facial Weakness; Fisher's One-and-a-Half Syndrome; Pendular Vertical Oscillations; Pontine Hemorrhage; Unilateral Gaze Palsy Hemorrhage; Unilateral Horizontal Gaze Palsy; Unilateral Internuclear Ophthalmoplegia; Upbeat Nystag...
12 Chiari I MalformationShirley H. Wray, MD, PhD, FRCPSee also: http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/295, http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/323, and http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/61Downbeat Nystagmus; Oscillopsia; Chiari-1 Malformation; Primary Position Downbeat Nystagmus; Vertical Saccadic Dysmetria; Horizontal Saccadic Dysmetria; Ataxia; Dysmetria; Chiari Malformation
13 Chiari-I MalformationShirley H. Wray, MD, PhD, FRCPA PowerPoint slideshow describing the condition.Ataxia; Chiari-1 Malformation; Downbeat Nystagmus; Dysmetria; Horizontal Saccadic Dysmetria; Lid Nystagmus; Oscillopsia; Primary Position Downbeat Nystagmus; Vertical Saccadic Dysmetria
14 Control of the Eye Movements: Neuroanatomy Video Lab - Brain DissectionsSuzanne S. Stensaas, PhDDisturbances in eye movements can provide important clues for localization of neurological damage. The role of the frontal eye fields in horizontal gaze is stressed. The need to coordinate cranial nerves on both sides of the brain stem introduces the medial longitudinal fasciculus and its role in co...Medial Longitudinal Fasciculus; Third Cranial Nerve; Sixth Cranial Nerve; Internuclear Ophthalmoplegia; Nystagmus; Brain; Dissection
15 Convergence-Retraction Nystagmus in Dorsal-Midbrain SyndromePaul Freund, MD, FRCSC; Edward Margolin, MD, FRCSCA man in his early twenties was referred by optometrist for abnormal eye motility findings. He had a remote history of an excised pinealoma. On exam he had almost complete upgaze palsy, convergence-retraction nystagmus on attempted upgaze, and light-near dissociation of pupillary reaction, the class...Dorsal Midbrain Syndrome; Parinaud Syndrome; Convergence-Retraction Nystagmus; Light-Near Dissociation
16 Downbeat NystagmusShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Downbeat Nystagmus; Oscillopsia
17 Downbeat NystagmusShirley H. Wray, MD, PhD, FRCPThis 58 year old engineer was referred by his neurologist for evaluation of periodic episodes of difficulty focusing and blurred vision for 8 years. In 1981 whilst sightseeing in Newport, he became acutely aware of difficulty focusing and blurry vision. The symptoms lasted for twenty minutes and the...Downbeat Nystagmus; Oscillopsia; Primary Position Downbeat Nystagmus
18 Downbeat Nystagmus Anti-GAD Cerebellar SyndromeRaed Behbehani, MDA patient with Anti-GAD positive Cerebellar syndrome with ataxia and opsoclonus due to downbeat nystagmus , treated with Baclofen with some improvement.Downbeat Nystagmus
19 Downbeat Nystagmus PANShirley H. Wray, MD, PhD, FRCPSlideshow describing condition.Downbeat Nystagmus; Periodic Alternating Nystagmus; Multiple Sclerosis
20 Downbeat Nystagmus PANShirley H. Wray, MD, PhD, FRCPThis patient carries a diagnosis of multiple sclerosis. See also: http://content.lib.utah.edu/cdm/ref/collection/ehsl-shw/id/317Downbeat Nystagmus; Periodic Alternating Nystagmus; Multiple Sclerosis; Primary Position Downbeat Nystagmus
21 Eyebrow SpasmDaniel J. Costello, MDSlideshow describing condition.Bipolar Affective Disorder; Epileptic Seizures; Primary Position Left Beating Nystagmus; Rhythmic Eyebrow Spasm; Torsional Nystagmus; Tuberous Sclerosis Complex (TSC-2 DNA sequence variant)
22 Eyebrow Spasm (Guest Lecture)Shirley H. Wray, MD, PhD, FRCPThis case is published courtesy of Daniel J. Costello, M.D., Department of Neurology, Massachusetts General Hospital, Boston. The patient is a 32-year-old right-handed man with an established diagnosis of Tuberous Sclerosis Complex characterized by: -medically intractable epilepsy -developmental del...Rhythmic Eyebrow Spasm; Torsional Nystagmus; Primary Position Left Beating Nystagmus; Epileptic Seizures; Tuberous Sclerosis Complex (TSC-2 DNA sequence variant); Bipolar Affective Disorder
23 Horizontal Gaze PalsyShirley H. Wray, MD, PhD, FRCPThis 56 year old woman with known adenocarcinoma of the breast presented with the recent onset of horizontal diplopia and deviation of her left eye inwards. Her oncologist referred her for a neuro-ophthalmic evaluation. This 56 year old woman with known adenocarcinoma of the breast presented with th...Unilateral Horizontal Gaze Palsy; Esotropia; Fascicular Sixth Nerve Palsy; Horizontal Gaze Evoked Nystagmus; Normal Convergence; Horizontal Oculocephalic Reflexes Absent; Facial Palsy (Bell's Palsy); Abducens Nuclear Lesion; Pontine Metastasis; Adenocarcinoma of the Breast; Unilateral Sixth Nerve Pa...
24 Horizontal Right Optokinetic NystagmusAnat Bachar Zipori, MD; Nasrin Najm-Tehrani, FRCS Ed (Ophth), FRCSCVisual depiction of the horizontal OKN drum test. The hand-held "optokinetic" drums or tapes that are used to elicit smooth movements primarily test the pursuit system. This video supplements Paediatric Neuro-ophthalmology: Visual Acuity Assessment Strategies: https://collections.lib.utah.edu/ark:/...Horizontal Right Optokinetic Nystagmus; OKN Drum Test
25 Internuclear Ophthalmoplegia in ChildhoodShirley H. Wray, MD, PhD, FRCPPowerPoint slideshow describing the condition.Abducting Nystagmus; Bilateral Internuclear Ophthalmoplegia; Medulloblastoma; Upbeat Nystagmus
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