The Alfredo A. Sadun Neuro-Ophthalmology Collection: A Professor of Ophthalmology and Neurological Surgery at the USC Keck School of Medicine, Dr. Sadun with a team of researchers at the Doheny Eye Institute pioneered research in optic nerve dysfunction in patients with Alzheimer's disease. Contains his "100 best lectures".
Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor Ophthalmology & Neurological Surgery, Doheny Eye Institute, Keck School of Medicine at USC
NOVEL: novel.utah.edu
Filters: Collection: "ehsl_novel_aas"
1 - 25 of 22
| Title | Creator | Description | Subject | Imaging | ||
|---|---|---|---|---|---|---|
| 1 |
 |
A Neuro-Ophthalmologist's View of RGC Apoptosis and Neuroprotection | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Slide presentation with several microscopic images demonstrating cell death, LHON, AIDS. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Phosphopyruvate Hydratase; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber; Acquired Immunodeficiency Syndrome; Glaucoma. Presen... | Optic Nerve; Retina; Retinal Ganglion Cells; Phosphopyruvate Hydratase; Apoptosis; Cell Death; Blindness; Ischemia; Retinal Detachment; Optic Atrophy, Hereditary, Leber; Acquired Immunodeficiency Syndrome; Glaucoma | |
| 2 |
 |
Anatomy and Physiology of the Optic Nerve | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Lecture covering the anatomy and physiology of the optic nerve. Covers the retina and anterior visual pathways. Several slides show microscopic images of optic nerve damage. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Cytokines. Disease/Diagnosis: Glaucoma. | Optic Nerve; Retina; Retinal Ganglion Cells; Cytokines; Apoptosis; Cell Death; Glaucoma; Anatomy of the Optic Nerve; AVP Optic Nerve | |
| 3 |
 |
Color Vision: Insights Into Our Origins and Some of Our Artists - From Darwin to Delacroix | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Discussion of origins and physiology of color vision in different species, distinction between addition and subtraction of colors, and how painters get around the difference. Includes microscopic views of retinal cones. Anatomy: Retina; Rods (Retina); Cones (Retina). | Color Perception; Retina; Rods (Retina); Cones (Retina); AVP Association Areas | |
| 4 |
 |
Anatomy and Physiology of Vision: The Visual Pathways | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Introduction to neuro-ophthalmology, covering the optic nerve, the afferent visual system (eye to brain), the pupil (Afferent-Efferent Reflex), and the efferent visual system (eye movements). Anatomy: Optic nerve; Optic disc; Retina; Retinal ganglion cells; Optic chiasm; Visual cortex. Disease/Diagn... | Optic Nerve; Optic Disc; Retina; Retinal Ganglion Cells; Optic Chiasm; Visual Cortex; Pituitary Adenoma; Optic Atrophy; Anatomy of Visual Pathways; Afferent Visual Pathways | |
| 5 |
 |
Beyond the Margulis Hypothesis: The Time Bomb Within Us | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Presented at 36th Annual Doheny Days, 2005. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. | Apoptosis; Cell Death; Optic Atrophy, Hereditary, Leber; Optic Nerve; Retina; Retinal Ganglion Cells; Reactive Oxygen Species | |
| 6 |
 |
Apoptosis of Retinal Ganglion Cells | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Presented at a conference on neuroprotection at Sedona, Arizona, 2002; includes several microscopic images demonstrating cell death. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Cytokines. Disease/Diagnosis: Glaucoma. | Optic Nerve; Retina; Retinal Ganglion Cells; Cytokines; Apoptosis; Cell Death; Glaucoma | |
| 7 |
 |
Distinguishing an Optic Neuropathy from a Maculopathy | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | PPT describing a case of optic neuropathy. Covers signs and symptoms, and various laboratory tests. Describes 10 signes of disc edema. Anatomy: Optic nerve; Retina; Retinal macula. Disease/Diagnosis: Optic nerve diseases; Retinal lesion; Macular lesion; Disorder of the optic nerve; Afferent pupillar... | Optic nerve diseases; Retinal lesion; Macular lesion; Disorder of the optic nerve; Afferent pupillary defect; Edema; Optic nerve; Retina; Retinal macula; Scotoma; Optic neuritis; Hyperopia; Metamorphopsia; Diseases of the Optic Nerve | |
| 8 |
 |
Distinguishing Optic Nerve vs. Retinal Lesions | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | PPT describing methods of distinguishing optic nerve verses retinal lesions. Describes a pateint case. Discussed signs, symtpoms and diagnostic tests. Anatomy: Optic nerve; Retina; Retinal macula. Disease/Diagnosis: Optic nerve diseases; Retinal lesion; Macular lesion; Disorder of the optic nerve; A... | Optic Nerve Diseases; Retinal Lesion; Disorder of the Optic Nerve; Macular Lesion; Retinal Macula; Afferent Pupillary Defect; Scotoma; Optic Neuritis; Hyperopia; Metamorphopsia; Optic Nerve; Retina; Diseases of the Optic Nerve | |
| 9 |
 |
Circadian Rhythms: How Much Retina Do We Need for a Good Night's Sleep? | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Discusses importance of the health of the retinohypothalamic tract in the maintenance of circadian rhythm. Anatomy: Retina; Hypothalamus; Retinal ganglion cells; Pineal gland. Disease/Diagnosis: Retinal diseases; Sleep disorders, Circadian rhythm. | Circadian Rhythm; Mole Rats; Retinal Diseases; Sleep Disorders; Retina; Hypothalamus; Retinal Ganglion Cells; Pineal Gland | |
| 10 |
 |
Optical Coherence Tomography (OCT) Applications in the Eye | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Optical Coherence Tomography is a technique for non-invasive cross-sectional imaging of ocular tissues. This PowerPoint covers an overview of the technique with excellent diagrams and images. Anatomy: Retina; Anterior eye segment; Cornea; Macula Lutea; Vitreous body; Optic nerve; Retinal ganglion ce... | Tomography, Optical Coherence; Retina; Anterior Eye Segment; Cornea; Macula Lutea; Vitreous Body; Optic Nerve; Retinal Ganglion Cells; Retinal Diseases; Glaucoma; Macular Edema; Retinal Edema; NFLA Optical Coherence Tomography | |
| 11 |
 |
The Visual Process: Tracing Light From the Retina to the Cortex | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Physiological basis of vision, including the optics of the eye and the retina and retinal pathways. Anatomy: Retina; Cortex | Vision; Color Perception; Retina; Cortex; Afferent Visual Pathways | |
| 12 |
 |
Why You Should Prescribe Goggles to a Box Jellyfish | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | A discussion of the box jellyfish eye and visual system. Anatomy: Retina; Lens, Crystalline. | Box jellyfish; Retina; Lens, Crystalline | |
| 13 |
 |
Visual Variants in Nature | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Comparison of visual systems of various species. Anatomy: Retina; Pupil; Cones (Retina); Rods (Retina); Lens, Crystalline. | Tokay Gecko; Cuttlefish; Scallop; Stalk-Eyed Gly; Sand Dab; Retina; Pupil; Cones (Retina); Rods (Retina); Lens, Crystalline | |
| 14 |
 |
How Mitochondria Orchestrate the Death of RGCs : From Brazil to Tuebingen to Rochester 2007 | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Slides showing LHON and Kjer's optic atrophy and images of optic disk with LHON. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia; Blindness. | Optic Nerve; Retina; Retinal Ganglion Cells; Reactive Oxygen Species; Scotoma; Telangiectasis; Apoptosis; Cell Death; Dyschromatopsia; Blindness; Optic Atrophy; Hereditary; Leber; Leber's Optic Neuropathy | |
| 15 |
 |
Headache and Visual Loss | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Presenting Symptom: Ataxia; Photophobia; Scotoma; Ischemia; Aura. Anatomy: Orbit; Retina; Serotonin. Disease/Diagnosis: Migraine disorders; Migraine with aura. Imaging: Ibuprofen; Sumatriptan; Pseudoephedrine; Lidocaine; Caffeine; Calcium channel blockers; Aminosalicylic acids. | Ataxia; Photophobia; Scotoma; Ischemia; Aura; Migraine Disorders; Migraine With Aura; Ibuprofen; Sumatriptan; Pseudoephedrine; Lidocaine; Caffeine; Calcium Channel Blockers; Aminosalicylic Acids; Orbit; Retina; Serotonin | |
| 16 |
 |
Headache | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Presenting Symptom: Ataxia; Photophobia; Scotoma; Ischemia; Aura. Anatomy: Orbit; Retina; Serotonin. Disease/Diagnosis: Migraine disorders; Migraine with aura. Treatment: Ibuprofen; Sumatriptan; Pseudoephedrine; Lidocaine; Caffeine; Calcium channel blockers; Aminosalicylic acids. | Migraine Disorders; Migraine With Aura; Aura; Ataxia; Photophobia; Scotoma; Ischemia; Orbit; Retina; Serotonin; Ibuprofen; Sumatriptan; Pseudoephedrine; Lidocaine; Caffeine; Calcium Channel Blockers; Aminosalicylic Acids; Headache and Facial Pain | |
| 17 |
 |
Engineering the Visual System | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Physiological basis of vision, covering perimetry, retinal ganglion cell types, and retinal pathways. Anatomy: Optic nerve; Retina. | Vision; Color Perception; Optic Nerve; Retina; Afferent Visual Pathways | |
| 18 |
 |
Mitochondrial Optic Neuropathy: Mitochondria as Gatekeepers for Apoptosis | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Anatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Scotoma; Dyschromatopsia. | Apoptosis; Cell Death; Optic Atrophy, Hereditary, Leber; Toxic Optic Neuropathy; Optic Nerve; Retina; Retinal Ganglion Cells; Reactive Oxygen Species; Amiodarone; Scotoma; Dyschromatopsia | |
| 19 |
 |
Neuroprotection = Apoptosis of Retinal Ganglion Cells | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Slide presentation with several microscopic images demonstrating cell death, LHON, AIDS. Presenting Symptom: Blindness; Ischemia; Retinal detachment. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Phosphopyruvate Hydratase. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber; Acquired Immunod... | Optic Nerve; Retina; Retinal Ganglion Cells; Phosphopyruvate Hydratase; Apoptosis; Cell Death; Blindness; Ischemia; Retinal Detachment; Optic Atrophy; Hereditary; Leber; Acquired Immunodeficiency Syndrome | |
| 20 |
 |
Optic Nerve Regeneration | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | A slide presentation with three sets of 3 views increasing magnification. Anatomy: Optic nerve; Retina. Disease/Diagnosis: Optic neuropathy, Ischemic; Retrograde degeneration; Necrosis. Treatment: Cerestat; Aptiganel; Memantine; Riluzole. | Nerve Regeneration; Optic Nerve; Retina; Retrograde Degeneration; Necrosis; Apoptosis; Cell Death; Cerestat; Aptiganel; Memantine; Riluzole | |
| 21 |
 |
Testing the Functional Patient | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Discusses testing to distinguish organic ailments from psychosomatic or willful simulation of symptoms. Anatomy: Optic nerve; Retina. Disease/Diagnosis: Optic nerve diseases; Retinal degeneration; Hysteria | Malingering; Hysteria; Optic Nerve; Retina; Optic Nerve Diseases; Retinal Degeneration | |
| 22 |
 |
Office Techniques for Detecting Optic Nerve Disease | Alfredo A. Sadun, MD, PhD, Flora L. Thornton Chair, Professor of Ophthalmology and Neurological Surgery, Keck School of Medicine at USC | Demonstration of brightness sense testing and of computer-generated graphics for Amsler grid testing. Presenting Symptom: Scotoma; Metamorphopsia. Anatomy: Optic nerve; Retina; Macula lutea. Disease/Diagnosis: Glaucoma; Optic neuritis; Macular degeneration. | Color Vision; Glaucoma; Macular Degeneration; Optic Neuritis; Scotoma; Metamorphopsia; Optic Nerve; Retina; Macula Lutea |
1 - 25 of 22