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TitleDescriptionSubjectCollection
1201 Infero-posterior MI with RBBBThis is an unusual RBBB because the initial R wave is taller than the R wave in lead V1. This is the clue for true posterior MI. The tall initial R wave in V1 is a pathologic R wave analagous to the pathologic Q wave of an anterior MI.Knowledge Weavers ECG
1202 Right Atrial Enlargement (RAE) & Right Ventricular Hypertrophy (RVH)RAE is recognized by the tall (>2.5mm) P waves in leads II, III, aVF. RVH is likely because of right axis deviation (+100 degrees) and the Qr (or rSR') complexes in V1-2.Knowledge Weavers ECG
1203 Frontal plane: accelerated junctional rhythm and inferior MIFrontal plane: accelerated junctional rhythm and inferior MIKnowledge Weavers ECG
1204 QRS axis = -30 degreesLead II is isoelectric; I is positive; III is negative. The axis is -30 degrees.Knowledge Weavers ECG
1205 Voltage criteria for LVHVoltage criteria for LVHKnowledge Weavers ECG
1206 Infero-posterior MIInfero-posterior MIKnowledge Weavers ECG
1207 RBBB - marquetteRBBB - marquetteKnowledge Weavers ECG
1208 Second degree AV block, type I, with bradycardia-dependent RBBBAn interesting and unusual form of rate-dependent bundle branch block. Normal sinus rhythm at 85 bpm is present with a 3:2 and 2:1 2nd degree AV block. The progressive PR prolongation in the 3:2 block makes this a type-I or Wenckebach block.Long cycles end in RBBB; short cycles have normal QRS dur...Knowledge Weavers ECG
1209 Bifascicular block: RBBB + LAFBThis is the most common of the bifascicular blocks. RBBB is most easily recognized in the precordial leads by the rSR' in V1 and the wide S wave in V6 (i.e., terminal QRS forces oriented rightwards and anterior). LAFB is best seen in the frontal plane leads as evidenced by left axis deviation (-50...Knowledge Weavers ECG
1210 Frontal plane lead diagramThe six frontal plane leads are illustrated with their respective positive and negative poles.When forced to intersect at a center point, the six leads inscribe a 360 degree circle. The normal frontal plane axis is from -30 degrees to + 90 degrees, shaded in grey. Left axis deviation is from -30 d...Knowledge Weavers ECG
1211 Anteroseptal MI: fully evolvedThe QS complexes, resolving ST segment elevation and T wave inversions in V1-2 are evidence for a fully evolved anteroseptal MI. The inverted T waves in V3-5, I, aVL are also probably related to the MI.Knowledge Weavers ECG
1212 Atrial parasystoleThe evenly spaced dots indicate ectopic atrial activity from a parasystolic atrial pacemaker. Non-fixed coupled PACs are seen having a common inter-ectopic interval. One of the PACs is nonconducted.Knowledge Weavers ECG
1213 Ventricular tachycardia - marquetteVentricular tachycardia - marquetteKnowledge Weavers ECG
1214 Long QT IintervalLong QT IntervalKnowledge Weavers ECG
1215 ECG of the century - part II: dual AV pathwaysAn astute cardiology fellow, yours truly, went to the patient's bedside on Day 2 and massaged the right carotid sinus as indicated by the arrow. Four beats later at a slightly slower heart rate the PR interval suddenly normalized suggesting an abrupt change from a slow AV nodal pathway to a fast AV...Knowledge Weavers ECG
1216 Left Atrial Enlargement & Nonspecific ST-T Wave AbnormalitiesLAE is best seen in V1 with a prominent negative (posterior) component measuring 1mm wide and 1mm deep. There are also diffuse nonspecific ST-T wave abnormalities which must be correlated with the patient's clinical status. Poor R wave progression in leads V1-V3, another nonspecific finding, is als...Knowledge Weavers ECG
1217 Atrial flutter with 3:2 AV conductionThis 12-lead ECG shows a subtle bigeminal rhythm resulting from atrial flutter with a 3:2 AV conduction ratio; RR intervals alternate by a small duration. This is uncommon! The impulses from the atrial flutter conduct through the AV junction in a Wenckebach sequence; for every 3 flutter waves the s...Knowledge Weavers ECG
1218 A very subtle 1st degree AV blockWhere are the P waves??? They are hiding in the T waves as indicated by the arrows. How do we know? The PVC unmasked the sinus P wave, and now it is seen in the pause following the PVC. The PR interval is, therefore, about 500 ms.Knowledge Weavers ECG
1219 PAC's with and without aberrant conduction - marquettePAC's with and without aberrant conduction - marquetteKnowledge Weavers ECG
1220 Ventricular fibrillation - marquetteVentricular fibrillation - marquetteKnowledge Weavers ECG
1221 Nonconducted PAC - marquetteNonconducted PAC - marquetteKnowledge Weavers ECG
1222 Trifascicular block: RBBB, LAFB, and mobitz II 2nd degree AV blockA nice example of trifascicular block: Lead V1 shows RBBB; Lead II is mostly negative with an rS morphology suggesting left anterior fascicular block. Since Mobitz II 2nd degree AV block is more often located in the bundle branch system, the only location left for this block is the left posterior ...Knowledge Weavers ECG
1223 2nd degree AV block, type I, with junctional escapesJunctional escapes are passive, protective events whenever the heart rate slows below that of the escape mechanism. In this example of 2nd degree AV block, type I, the escapes occur following the non-conducted P waves. Arrows indicate the position of the P waves. Note that the escape beats have a...Knowledge Weavers ECG
1224 Atrial flutter with 2:1 AV conductionAtrial flutter with 2:1 AV block is one of the most frequently missed ECG rhythm diagnoses because the flutter waves are often hard to find. In this example two flutter waves for each QRS are best seen in lead III and V1. The ventricular rate at 150 bpm should always prompt us to consider atrial fl...Knowledge Weavers ECG
1225 Identification of PVC's and PAC'sPVC's usually stick out like sore thumbs; PAC's are often difficult to see because they are hidden in the preceding ST-T wave. The PVC in this example is mostly negative in lead V1 suggesting RV origin; i.e., most of activation is moving in posterior direction towards the left ventricle.Knowledge Weavers ECG
1226 AV dissociation by defaultThe nonconducted PAC's set up a long pause which is terminated by ventricular escapes; note the wider QRS morphology of the escape beats indicating their ventricular origin. Incomplete AV dissociation occurs during the escape beats, since the atria are still under the control of the sinus node.Knowledge Weavers ECG
1227 Lead error: V1 and V3 are transposed!In the precordial leads the V1 and V3 chest electrodes are interchanged. Experienced ECG interpreters should be able to spot this lead placement error.Knowledge Weavers ECG
1228 Infero-posterior MI & RBBB: Frontal Plane Leads + V1Infero-posterior MI & RBBB: Frontal Plane Leads + V1Knowledge Weavers ECG
1229 WPW Type Pre-excitation: Precordial LeadsWPW Type Pre-excitation: Precordial LeadsKnowledge Weavers ECG
1230 Acute anterior MIAcute anterior MIKnowledge Weavers ECG
1231 2nd degree AV block, type I with escapes and capturesOften in the setting of 2nd degree AV block the pauses caused by nonconducted P waves are long enough to enable escape pacemakers from the junction or ventricles to take over. This example illustrates junctional escapes, labled E and captures, labled C. Note that the PR intervals for the captures ...Knowledge Weavers ECG
1232 Ventricular paced rhythm with retrograde wenckebachRetrograde atrial captures from a ventricular paced rhythm are occurring with increasing R-P intervals; i.e., retrograde Wenckebach. The ladder diagram indicates that after the blocked retrograde event, a single sinus P wave is seen dissociated from the ventricular rhythm.Wenckebach AV BlockKnowledge Weavers ECG
1233 Nonconducted PAC's: an unusual bigeminyOccasionally nonconducted PAC's can create interesting rhythms. In this example every other sinus beat is followed by an early, nonconducted PAC. The resulting pause sets up a bigeminal rhythm. Note the distortion of the T waves caused by the nonconducted PAC's.Knowledge Weavers ECG
1234 Atrial flutter with 2:1 AV conduction: leads II, III, V1In leads II and III, the one of the flutter waves occurs at the end of the QRS complex and might be mistaken for part of the QRS itself; i.e., the S wave. In lead V1, the two flutter waves for every QRS are more easily identified.Knowledge Weavers ECG
1235 Accelerated IVR with AV dissociation - marquetteAccelerated IVR with AV dissociation - marquetteKnowledge Weavers ECG
1236 Old inferior MIOld inferior MIKnowledge Weavers ECG
1237 Diagram: type I vs. type II 2nd degree AV blockIn type I 2nd degree AV block the PR progressively lengthens until a nonconducted P wave occurs. The PR gets longer by smaller and smaller increments; this results in gradual shortening of the RR intervals. The RR interval of the pause is usually less than the two preceding RR intervals. The RR i...Knowledge Weavers ECG
1238 PAC's with RBBB aberrationThese PAC's, indicated by arrows, enter the ventricles and find the right bundle refractory. They therefore conduct with RBBB aberrancy. In most normal hearts the right bundle recovery time is longer than the left bundle's; most aberrancy, therefore, has aRBBB morphology. In some diseased hearts t...Knowledge Weavers ECG
1239 RBBB + LAFB = bifascicular blockThe RBBB is diagnosed by the wide QRS with prominent anterior (e.g., V1) and late rightward (e.g., I, V6) forces. The LAFB is recognized by the marked left axis deviation (-75 degrees) in the frontal plane, rS complexes in II, III, aVF, and the tiny q-wave in aVL.Knowledge Weavers ECG
1240 Massage parlor gamesWhen unsure of the mechanism of a supraventricular tachycardia, carotid sinus massage may help make the diagnosis. In this example, carotid sinus massage causes marked AV block which permits easy recognition of the rapid, regular atrial flutter waves.Knowledge Weavers ECG
1241 Wandering baseline artifact - marquetteWandering baseline artifact - marquetteKnowledge Weavers ECG
1242 Frontal plane QRS axis = +15 degreesFrontal plane QRS axis = +15 degreesKnowledge Weavers ECG
1243 Frontal plane QRS axis = +30 degreesFrontal plane QRS axis = +30 degreesKnowledge Weavers ECG
1244 Acute inferoposterior MIAcute inferoposterior MIKnowledge Weavers ECG
1245 Sinus bradycardiaSinus bradycardiaKnowledge Weavers ECG
1246 2nd degree AV block, mobitz type II, with LBBBThe wide QRS complexes in lead V1 indicates LBBB. 2nd degree AV block, Mobitz II is suggested by the two fixed PR intervals prior to the nonconducted P wave. The location of the block is most likely in the right bundle, because Mobitz II is usually a sign of bilateral bundle branch disease.Knowledge Weavers ECG
1247 A very subtle atrial tachycardia with 2:1 blockAlthough at first glance this looks like normal sinus rhythm at 95 bpm. On closer look, there are 2 P waves for every QRS; the atrial rate is 190 bpm. Note the hidden P in the T waves. This rhythm is likely due to digitalis intoxication, as are the GI symptoms.Knowledge Weavers ECG
1248 Left atrial enlargementLeft atrial enlargement is illustrated by increased P wave duration in lead II, top ECG, and by the prominent negative P terminal force in lead V1, bottom tracing.Knowledge Weavers ECG
1249 Acute postero-lateral MI: precordial leadsAcute postero-lateral MI: precordial leadsKnowledge Weavers ECG
1250 Pacemaker failure to pace - marquettePacemaker failure to pace - marquetteKnowledge Weavers ECG
1251 Frontal plane QRS axis = 90 degreesFrontal plane QRS axis = 90 degreesKnowledge Weavers ECG
1252 Junctional tachycardia - marquetteJunctional tachycardia - marquetteKnowledge Weavers ECG
1253 Diagram: frontal plane leadsDiagram: frontal plane leadsKnowledge Weavers ECG
1254 Inferoposterior MIInferoposterior MIKnowledge Weavers ECG
1255 Digitalis intoxication: Junctional tachycardia with and without AV blockIn a patient with longstanding atrial fibrillation being treated with digoxin, a regular tachycardia, as seen in A, with a RBBB suggests a junctional or supraventricular tachycardia. Group beating, in B, is likely due to a 2nd degree, Type 1, exit block below the ectopic junctional focus. This is h...Knowledge Weavers ECG
1256 Nonconducted PACs and junctional escapesAlthough at first glance this looks like 2nd degree AV block, the P waves indicated by the arrows are premature and not sinus P waves. The pause is long enough to encourage a junctional escape focus to take over. Note the sinus P waves just before the escape beats. Had the escapes not occurred, t...Knowledge Weavers ECG
1257 WPW diagramThe short PR interval is due to a bypass track, also known as the Kent pathway. By bypassing the AV node the PR shortens. The delta wave represents early activation of the ventricles from the bypass tract. The fusion QRS is the result of two activation sequences, one from the bypass tract and one...Knowledge Weavers ECG
1258 PVC with venticular echoThe PVC in this example retrogradely enters the AV junction and returns, usually down a different pathway, to reactivate the ventricles....a ventricular echo. This is unlikely to be an interpolated PVC because the PR interval following the PVC is too short for the sinus impulse to have entered the ...Knowledge Weavers ECG
1259 Left bundle branch block (LBBB)LBBB is recognized by 1) QRS duration>0.12s; 2) monophasic R waves in I and V6; and 3) terminal QRS forces oriented leftwards and posterior. The ST-T waves should be oriented opposite to the terminal QRS forces.Knowledge Weavers ECG
1260 PAC with RBBB aberrant conductionPAC with RBBB aberrant conductionKnowledge Weavers ECG
1261 Interpolated PVCs - marquetteInterpolated PVCs - marquetteKnowledge Weavers ECG
1262 PVC triplet - marquettePVC triplet - marquetteKnowledge Weavers ECG
1263 Ventricular tachycardia with retrograde wenckebachApproximately 50 percent of ventricular tachycardias are associated with AV dissociation. The other 50 percent have retrograde atrial capture. This example shows ventricular tachycardia with retrograde Wenckebach. The retrograde P waves are hard to find, but the arrows are of some help.Wenckebach AV BlockKnowledge Weavers ECG
1264 Nonconducted and aberrantly conducted PAC'sIn A the slow sinus rhythm is actually caused by nonconducted PACs hidden in the ST segment. This is confirmed in B where some of the PACs are aberrantly conducted with LBBB, and some PACs are nonconducted.Knowledge Weavers ECG
1265 Left anterior fasicular block: frontal plane leadsLeft anterior fascicular block, LAFB, is recognized by left axis deviation of -45 degrees or greater; rS complexes in II, III, aVF; and a small Q wave in I and/or aVL.Knowledge Weavers ECG
1266 Right bundle branch block (RBBB)Right bundle branch block (RBBB)Knowledge Weavers ECG
1267 All about premature beatsAll about premature beatsKnowledge Weavers ECG
1268 Inferoposterior MIInferoposterior MIKnowledge Weavers ECG
1269 Sino-atrial exit block, type I or wenckebachThis example illustrates 2nd degree sino-atrial exit block. In type 1 S-A block the conduction time between sinus firing and atrial capture progressively prolong, but this cannot be seen on the ECG tracing; type I exit block is inferred if the P-P intervals gradually shorten before the pause and if...Wenckebach AV Block; Ladder DiagramKnowledge Weavers ECG
1270 Inferior & Anteroseptal MI + RBBBPathologic Q waves are seen in leads II, III, aVF (inferior MI) and in leads V1-3 (anteroseptal MI). RBBB is recognized by the wide QRS (>0.12s) and the anterior/rightwards orientation of terminal QRS forces. When an anteroseptal MI complicates RBBB (or visa versa) the rSR' complex in V1 (typical ...Knowledge Weavers ECG
1271 Atrial flutter with 3:2 conduction ratio: frontal plane leadsNote the subtle bigeminy in the RR intervals. The best way to identify the flutter waves in this example is to imagine what lead III would look like if the QRS complexs disappeared; what remains is a reasonable saw-tooth pattern characteristic of atrial flutter with a flutter rate of about 300 bpm...Knowledge Weavers ECG
1272 Accelerated ventricular rhythm with retrograde atrial capture and echo beatsRetrograde atrial captures from an accelerated ventricular focus are occurring with increasing R-P intervals, When the longer R-P occurs, the impulse traversing the AV junction finds a route back to the ventricles, and the result is a ventricular echo.Knowledge Weavers ECG
1273 ECG components diagram - marquetteECG components diagram - marquetteKnowledge Weavers ECG
1274 Postero-lateral MI: Precordial LeadsPostero-lateral MI: Precordial LeadsKnowledge Weavers ECG
1275 Indeterminate frontal plane QRS axisIndeterminate frontal plane QRS axisKnowledge Weavers ECG
1276 PAC couplet - marquettePAC couplet - marquetteKnowledge Weavers ECG
1277 Normal variant: Early repolarizationEarly repolarization, a misnomer, describes a pattern of localized or diffuse ST segment elevation. This is especially seen in leads with prominent R waves. In this example leads I, II, V5 and V6 illustrate the early repolarization pattern. ST segments usually have a concave upwards pattern and ta...Knowledge Weavers ECG
1278 AV dissociation by usurpationNormal sinus rhythm is interrupted by an accelerated ventricular rhythm whose rate is slightly faster than the sinus rhythm. Fusion QRS complexes occur whenever the sinus impulse enters the ventricles at the same time the ectopic ventricular focus initiates its depolarization.Knowledge Weavers ECG
1279 Long QT mischiefThe long QT ECG has many causes: electrolyte abnormalities including hypo-K, hypo-Mg, and hypo-Ca; drugs including type I antiarrhythmics; CNS injury; and hereditary syndromes. Ventricular arrhythmias are thought to be caused by afterdepolarizations or triggered automaticity.Knowledge Weavers ECG
1280 Nonconducted and conducted PAC'sThe pause in this example is the result of a nonconducted PAC, as indicated by the first arrow. The second arrow points to a conducted PAC. The most common cause of an unexpected pause in rhythm is a nonconducted PAC.Knowledge Weavers ECG
1281 Atypical LBBB with Q waves in leads I and aVLIn typical LBBB, there are no initial Q waves in leads I, aVL, and V6. If Q waves are present in 2 or more of these leads, myocardial infarction is present.Knowledge Weavers ECG
1282 Old inferior MI, PVCs, and atrial fibrillationOld inferior MI, PVCs, and atrial fibrillationKnowledge Weavers ECG
1283 Frontal plane QRS axis = -45 degreesFrontal plane QRS axis = -45 degreesKnowledge Weavers ECG
1284 LVH & PVCs: Precordial LeadsLVH & PVCs: Precordial LeadsKnowledge Weavers ECG
1285 Atrial flutter with variable AV block and rate-dependent LBBBThe basic rhythm is atrial flutter with variable AV block. When 2:1 conduction ratios occur there is a rate-dependent LBBB. Don't be fooled by the wide QRS tachycardia on the bottom strip. It's not ventricular tachycardia, but atrial flutter with 2:1 conduction and LBBB. Lidocaine is not needed ...Knowledge Weavers ECG
1286 three fates of PAC'sAs illustrated, PAC's can have three fates: PAC-1enters the ventricles and encounters no conduction delays, therefore causing a narrow QRS; PAC-2 occurs a little earlier and can't get through the AV junction, therefore beingnonconducted; PAC-3 seen inlead V1 makes it into the ventricles but encounte...Knowledge Weavers ECG
1287 Ventricular tachycardia with AV dissociation, captures, and fusionsApproximately 50 percent of ventricular tachycardias are associated with AV dissociation. In these cases atrial impulses can enter the ventricles and either fuse with a ventricular ectopic beat or completely capture the ventricles. This ladder diagram illustrates these events.Knowledge Weavers ECG
1288 Frontal plane QRS axis = +75 degreesSince there is no isoelectric lead in this ECG, the two closest leads are I and aVL. If I were isoelectric, the axis would be +90 degrees; if aVL were isoelectric, the axis would be +60 degrees. A nice compromize is +75 degrees. (The two closest leads are always 30 degrees apart.)Knowledge Weavers ECG
1289 Right axis deviation: QRS axis = +130 degreesLead aVR is almost isoelectric; lead I is mostly negative, and lead III is very positive. The QRS axis, therefore, is +130 degrees. Note that the slightly more positive AVR moves the axis slightly beyond +120 degrees; i.e., closer to the + pole of the aVR lead.Knowledge Weavers ECG
1290 Extensive anterior/anterolateral MI: precordial leadsExtensive anterior/anterolateral MI: precordial leadsKnowledge Weavers ECG
1291 LVH: strain pattern + left atrial enlargementLVH: strain pattern + left atrial enlargementKnowledge Weavers ECG
1292 Ventricular asystole - marquetteVentricular asystole - marquetteKnowledge Weavers ECG
1293 Multifocal PVC's - marquetteMultifocal PVC's - marquetteKnowledge Weavers ECG
1294 Atrial flutter with 2:1 AV conductionIn this example of atrial flutter with 2:1 AV conduction the flutter waves are very hard to see. Atrial flutter with 2:1 block must be considered, however, because the heart rate is about 150 bpm. A careful look at V1 shows the two flutter waves for each QRS complex complex. One flutter wave imme...Knowledge Weavers ECG
1295 Ventricular parasystoleIn ventricular parasystole, non-fixed coupled PVC's occur at a common inter-ectopic interval. Fusion beats, indicated by arrows, are often seen. Fusions occur when the sinus impulse entering the ventricles find the ventricles already partially depolarized by the parasystolic focus.Knowledge Weavers ECG
1296 Atrial flutter with 2:1 and 4:1 conduction and rate dependent LBBBIn this example of atrial flutter with variable AV conduction, the faster rates are associated with rate-related LBBB. Don't confuse this for ventricular tachycardia.Knowledge Weavers ECG
1297 2nd degree AV block, type I (Wenckebach)2nd degree AV block, type I (Wenckebach)Knowledge Weavers ECG
1298 Diagram: stages of acute Q-wave MIDiagram: stages of acute Q-wave MIKnowledge Weavers ECG
1299 Accelerated junctional rhythmAccelerated junctional rhythmKnowledge Weavers ECG
1300 PVC's - marquettePVC's - marquetteKnowledge Weavers ECG
1301 2nd degree AV block with junctional escapes and capturesSecond degree AV block is present; conducted beats are identified by those QRS's that terminate shorter cycles than the junctional escape cycle; i.e., the 3rd and probably the 4th QRS's are captures; the other QRS's are junctional escapes.Knowledge Weavers ECG
1302 Atrial fibrillation with moderate ventricular response - MarquetteAtrial fibrillation with moderate ventricular response - MarquetteKnowledge Weavers ECG
1303 Ventricular pacing in atrial fibrillation - marquetteVentricular pacing in atrial fibrillation - marquetteKnowledge Weavers ECG
1304 Ventricular pacemaker: demand mode functioningVentricular pacemaker: demand mode functioningKnowledge Weavers ECG
1305 Ventricular escape beat - marquetteVentricular escape beat - marquetteKnowledge Weavers ECG
1306 LAFB: frontal plane leadsLAFB: frontal plane leadsKnowledge Weavers ECG
1307 Old infero-posterior MIOld infero-posterior MIKnowledge Weavers ECG
1308 2nd degree AV block, type IThe 3 rules of classic AV Wenckebach are: 1. decreasing RR intervals until pause; 2. the pause is less than preceding 2 RR intervals; and 3. the RR interval after the pause is greater than the RR interval just prior to pause. Unfortunately, there are many examples of atypical forms of Wenckebach wh...Wenckebach AV BlockKnowledge Weavers ECG
1309 Atrial echosIn this example a typical Wenckebach sequence is interrupted by what looks like a PAC - indicated by red arrows. Atrial echos are more likely, however, because the preceding beat has a long PR interval, a condition that facilitates reentry and echo formation.Knowledge Weavers ECG
1310 Anteroseptal MI with RBBB: precordial leadsAnteroseptal MI with RBBB: precordial leadsKnowledge Weavers ECG
1311 Cardiac conduction system diagram - marquetteCardiac conduction system diagram - marquetteKnowledge Weavers ECG
1312 ST segment depression: precordial leadsST segment depression: precordial leadsKnowledge Weavers ECG
1313 Idioventricular escape rhythmIdioventricular escape rhythmKnowledge Weavers ECG
1314 Unifocal PVCs - marquetteUnifocal PVCs - marquetteKnowledge Weavers ECG
1315 Two Wrongs Sometimes Make a RightThe question mark is over a normal looking QRS that occurs during 2:1 AV block with RBBB. Following this QRS a ventricular escape rhythm takes over. The normal looking beat is actually a fusion beat resulting from simultaneous activation of the ventricles; the sinus impulse enters the left ventric...Knowledge Weavers ECG
1316 WPW type preexcitationNote the short PR and the subtle delta wave at the beginning of the QRS complexes. The delta wave represents early activation of the ventricles in the region where the AV bypass tract inserts. The rest of the QRS is derived from the normal activation sequence using the bundle branches.Knowledge Weavers ECG
1317 Long QT intervalThe QT interval duration is greater than 50% of the RR interval, a good indication that it is prolonged in this patient. Although there are many causes for the long QT, patients with this are at risk for malignant ventricular arrhythmias, syncope, and sudden death.Knowledge Weavers ECG
1318 Wandering atrial pacemakerWandering atrial pacemaker is a benign rhythm change where the pacemaker site shifts from the sinus node into the atrial tissues. P-wave morphology varies with the pacemaker site.Knowledge Weavers ECG
1319 QRS axis = +60 degreesLead aVL is isoelectric; leads II and III are mostly positive. The QRS axis, therefore, is +60 degrees.Knowledge Weavers ECG
1320 Electronic ventricular pacemaker rhythm - marquetteElectronic ventricular pacemaker rhythm - marquetteKnowledge Weavers ECG
1321 High lateral wall MI (seen in aVL)High lateral wall MI (seen in aVL)Knowledge Weavers ECG
1322 Atrial tachycardia - marquetteAtrial tachycardia - marquetteKnowledge Weavers ECG
1323 LVH with StrainLVH with StrainKnowledge Weavers ECG
1324 PAC's with RBBB aberrant conductionPAC's are identified by the arrows. Note that the PP interval surrounding the PAC is less than 2x the basic sinus cycle indicating that the sinus node has been reset by the ectopic P wave. The pause after the PAC, therefore, is incomplete.Knowledge Weavers ECG
1325 1st degree AV blockThe normal PR interval is 0.12 - 0.20 sec, or 120 -to- 200 ms. 1st degree AV block is defined by PR intervals greater than 200 ms. This may be caused by drugs, such as digoxin; excessive vagal tone; ischemia; or intrinsic disease in the AV junction or bundle branch system.Knowledge Weavers ECG
1326 Sore thumbsTwo funny looking premature beats are seen in this rhythm strip. Beat A is preceded by a PAC which distorts the T wave, making this an aberrantly conducted PAC. Beat B is a PVC. The notch on the down slope of the QRS complex clearly identifies this as a PVC and not aberrancy.Knowledge Weavers ECG
1327 AV dissociation by defaultIf the sinus node slows too much a junctional escape pacemaker may take over as indicated by arrows. AV dissociation is incomplete, since the sinus node speeds up and recaptures the entricles.Knowledge Weavers ECG
1328 Atrial tachycardia with 2:1 AV block: a manifestation of digitalis intoxicationAtrial tachycardia with 2:1 AV block: a manifestation of digitalis intoxicationKnowledge Weavers ECG
1329 Accelerated junctional rhythm - marquetteAccelerated junctional rhythm - marquetteKnowledge Weavers ECG
1330 First degree AV block - marquetteFirst degree AV block - marquetteKnowledge Weavers ECG
1331 AV sequential pacemaker - marquette(Summary)Knowledge Weavers ECG
1332 Postero-lateral MI: Fully EvolvedThe true posterior MI is recognized by pathologic R waves in leads V1-2. These are the posterior equivalent of pathologic Q waves (seen from the perspective of the anterior leads). Tall T waves in these same leads are the posterior equivalent of inverted T waves in this fully evolved MI. The loss o...Knowledge Weavers ECG
1333 Atrial tachycardia with 3:2 and 2:1 AV blockThe ectopic atrial rate is 150 bpm. Some of the ectopic P waves are easily seen and indicated by the arrows. Other P waves are burried in the T waves and not so easily identified. Atrial tachycardia with AV block is often a sign of digitalis intoxication. 3:2 and 2:1 AV block is seen in this examp...Knowledge Weavers ECG
1334 RBBB with primary ST-T wave abnormalitiesRBBB is recognized by 1) rR' in V1; 2) QRS duration>0.12s; 3) terminal QRS forces oriented rightwards and anterior. In RBBB the ST-T waves should be oriented opposite to the terminal QRS forces. In this example there areprimary ST-T wave abnormalitiesin leads I, II, aVL, V5, V6. In these leads th...Knowledge Weavers ECG
1335 What are those funny looking beats????The differential diagnosis of funny-looking-beats, or FLB's, primarily considers beats of supraventricular origin with aberrant conduction and ventricular ectopic beats. In this example the two FLB's have an easily seen ectopic P wave before them; therefore these are PAC's with RBBB aberration.Knowledge Weavers ECG
1336 Conceptual framework: aArrhythmias and conduction abnormalitiesConceptual framework: aArrhythmias and conduction abnormalitiesKnowledge Weavers ECG
1337 Atrial flutter with variable AV block - marquetteAtrial flutter with variable AV block - marquetteKnowledge Weavers ECG
1338 Compensatory vs. non-compensatory pauses - marquetteCompensatory vs. non-compensatory pauses - marquetteKnowledge Weavers ECG
1339 Propionyl CoA production from odd-chain fatty acidsBeta-oxidation of fatty acids with an odd number of carbons inthe chain yields the three-carbon propionyl CoA as the final fragment.BiosynthesisKnowledge Weavers Fatty Acids
1340 Transfer of a malonyl group to the acyl carrier peptideDuring fatty acid synthesis the incoming two carbon fragment is introduced as the three-carbon malonyl group. It is added to the -SH group of the acyl carier peptide domain of fatty acid synthase. In a subsequent reaction the carbon shown in green will be lost as bicarbonate ion.Knowledge Weavers Fatty Acids
1341 Transport of fatty acyl CoA into mitochondria by the carnitine shuttleFatty acyl CoA cannot cross the inner mitochondrial membrane, so it is carried in the form of fatty acyl carnitine.Knowledge Weavers Fatty Acids
1342 Hydroxymethylglutaryl CoA lyase reactionIn this mitochondrial process hydroxymethylglutaryl CoA is converted to acetoacetate, a ketone body. Acetyl CoA is another product.Knowledge Weavers Fatty Acids
1343 Acetyl CoA metabolism -- overviewMajor metabolic sources of acetyl CoA and some of the processes in which it serves as a substrate.Knowledge Weavers Fatty Acids
1344 Oleic acid structureOleic acid is a typical monounsaturated fatty acid.Knowledge Weavers Fatty Acids
1345 methylmalonyl CoA mutase reactionIn the metabolism of propionyl CoA L-methylmalonyl CoA is converted to succinate by methylmalonyl CoA mutase. Succinate can then be metabolized throgh the tricarboxylic acid cycle.Knowledge Weavers Fatty Acids
1346 Mammalian fatty acyl synthase dimerThis schematic diagram is intended to show the sequence of enzyme activities in the two subunits of a mammalian fatty acyl synthase dimer. It is not intended to imply anything about the detailed spatial relationships of the activities.Coenzyme A SynthetasesKnowledge Weavers Fatty Acids
1347 Hydration of an enoyl CoAHydration of the double bond is catalyzed by enoyl CoA hydratase. The product is an L-3-hydroxyacyl CoA. This reaction is a step in the beta-oxidation of fatty acids.Knowledge Weavers Fatty Acids
1348 Acetyl CoA structureAcetyl CoA Structure. The thioester bond linking the acetyl group to CoA is ahigh energybond.Knowledge Weavers Fatty Acids
1349 Use of greek letters to designate carbons in fatty acidsThe carbon next to the -COOH group is the alpha carbon; the next one is the beta carbon, and so forth. The carbon most distant from the -COOH group is designated omega. Carbons close to the omega carbon may be designated in relation to it. E.g., the third carbon from the end is omega - 3, and the...NomenclatureKnowledge Weavers Fatty Acids
1350 Acylation of carnitine by a long chain fatty acyl CoALong chain fatty acyl CoA cannot cross the inner mitochondrial membrane to participate in beta-oxidation. The fatty acyl group is therefore transferred to a carrier, carnitine, in a reversible reaction catalyzed by carnitine acyl transferase I. The resulting fatty acyl carnitine crosses the membra...Knowledge Weavers Fatty Acids
1351 Four systems for denoting fatty acidsThere are four commonly used ways of designating fatty acids. The first two columns show samples of names, and the last two columns show systems of abbreviating these names.NomenclatureKnowledge Weavers Fatty Acids
1352 Reduction of 2-enoyl acyl carrier peptideA 2-enoyl acyl group on the acyl carrier peptide is reduced by NADPH in a reaction catalyzed by enoyl acyl carrier peptide reductase.Knowledge Weavers Fatty Acids
1353 methylmalonyl CoA racemase reactionIn the metabolism of propionyl CoA, D-methylmalonyl CoA is produced by a carboxylase reaction. This product must be converted to L-methylmalonyl CoA in order to be metabolized further. The conversion is catalyzed by methylmalonyl CoA racemase.Knowledge Weavers Fatty Acids
1354 Oxidation of a polyunsaturated fatty acid -- part IThe cycles of beta-oxidation prior to the one involving the original Delta-12 double bond act to get past the Delta-9 double bond.Knowledge Weavers Fatty Acids
1355 enoyl CoA isomerase reactionEnoyl CoA isomerase converts a trans-3-enoyl CoA to a trans-2-enoyl CoA. Thus a Delta-9 fatty acyl CoA or the product of the 2,4-dienoyl CoA reductase reaction can proceed through beta-oxidation.Enoyl CoA Isomerase ReactionKnowledge Weavers Fatty Acids
1356 Structures of the ketone bodiesThese are the structures of the ketone bodies. Acetoacetate and beta-hydroxybutyrate are important physiological substrates. Acetone is a byproduct, and is not metabolized further. It is excreted in the urine and in expired air.Knowledge Weavers Fatty Acids
1357 Triacylglycerol structureThe structure of a typical triacylglycerol (triglyceride).Knowledge Weavers Fatty Acids
1358 Dehydrogenation of fatty acyl CoAFatty acyl CoA is dehydrogenated by FAD in a reaction catalyzed by one of the acyl CoA dehydrogenases. Note that the dehydrogenation occurs between the alpha- and beta-carbons.FADKnowledge Weavers Fatty Acids
1359 Reduction of acetoacetateAcetoacetate is reduced by NADH in a reversible reaction catalyzed by beta-hydroxybutyrate dehydrogenase. This reaction is the source of beta-hydroxybutyrate in the blood of individuals with ketosis.Knowledge Weavers Fatty Acids
1360 Hydroxymethylglutaryl CoA synthase reactionThis irreversible reaction occurs in the mitochondria, where it is the first step in ketone body synthesis. It also occurs in the cytoplasm, where it leads to isoprenoid and steroid synthesis.BiosynthesisKnowledge Weavers Fatty Acids
1361 Thiolase reactionThiolase (3-ketoacyl CoA thiolase) cleaves a long chain fatty acyl CoA, forming acetyl CoA and a long chain fatty acyl CoA that is two carbons shorter.Knowledge Weavers Fatty Acids
1362 Beta-oxidation of a delta-9 fatty acyl CoAEnoyl CoA isomerase is required to move the double bond in a Delta-9 fatty acyl CoA to a position where it can continue in beta-oxidation.Knowledge Weavers Fatty Acids
1363 Thiolase reaction with acetoacetyl CoAThiolase (3-ketoacyl CoA thiolase) cleaves acetoacetyl CoA, forming two molecules of acetyl CoA.Knowledge Weavers Fatty Acids
1364 Stearic acid structureStearic acid is a typical long chain saturated fatty acid.Knowledge Weavers Fatty Acids
1365 Fatty acid elongation in mitochondriaThis shows the overall reaction of fatty acid elongation in mitochondria. The process is essentially a reversal of beta-oxidation, except that one NADPH and one NADH are required (beta-oxidation yields two NADH). Mitochondrial fatty acid elongation acts primarily on fatty acyl CoA substrates short...Knowledge Weavers Fatty Acids
1366 Fatty acyl CoA elongation in the endoplasmic reticulumThis shows the overall process of fatty acyl elongation in the endoplasmic reticulum. The process resembles that catalyzed by fatty acyl synthase, but the individual activities appear to be on separate enzymes.Knowledge Weavers Fatty Acids
1367 Propionyl CoA carboxylase reactionPropionyl CoA is metabolized by a process that first converts it to D-methylmalonyl CoA. The reaction is catalyzed by propionyl CoA carboxylase,and requires energy in the form of ATP.BiosynthesisKnowledge Weavers Fatty Acids
1368 Linoleic acid structureLinoleic acid is a typical polyunsaturated fatty acid.Knowledge Weavers Fatty Acids
1369 Reduction of a 2,4-dienoyl CoAThe reduction of 2,4-dienoyl CoA by NADPH is a step in the oxidation of polyunsaturated fatty acids. It is ironic that a reduction reaction is a required step in a process that is oxidative.Knowledge Weavers Fatty Acids
1370 Stearic, oleic and linoleic acid structuresStearic, oleic and linoleic acid structuresKnowledge Weavers Fatty Acids
1371 Complete oxidation of an odd-chain fatty acid -- overviewThis diagram indicates production of propionyl CoA from an odd-chain fatty acid and the subsequent conversion of propionyl CoA to succinyl CoA, which can be metabolized through the citric (tricarboxylic) acid cycle.BiosynthesisKnowledge Weavers Fatty Acids
1372 Initiation of beta-oxidationAn acetyl group is transferred from acetyl CoA to the -SH group of the condensing enzyme domain of fatty acyl synthase, forming acetyl-CE. The reaction is catalyzed by the acyltransferase activity of fatty acyl synthase.Knowledge Weavers Fatty Acids
1373 Fatty acid metabolism -- schematic overviewFatty acids are taken up by cells, where thy may serve as precursors in the synthesis of other compounds, as fuels for energy production, and as substrates for ketone body synthesis. Ketones bodies may then be exported to other tissues, where they can be used for energy production.BiosynthesisKnowledge Weavers Fatty Acids
1374 Condensation of an acyl group with a malonyl groupThe acetyl group displaces the carboxyl of the malonyl group, forming a beta-ketoacyl group. This reaction is catalyzed by beta-ketoacyl Acyl Carrier Peptide synthase. The carboxyl released in the form of bicarbonate regenerates the bicarbonate used earlier in the acetyl CoA carboxylase reaction.Knowledge Weavers Fatty Acids
1375 Essential features of a fatty acidThe essential features of a fatty acid are a long hydrocarbon chain terminating in a carboxylic acid group.Knowledge Weavers Fatty Acids
1376 Corpus luteum cysts exhibit a convoluted lining with luteinized granulosa and theca cells.Corpus luteum of the ovary, medium power. The granulosa cells have undergone proliferation and alteration to lutein cells that produce progesterone. The lutein cells are large and polyhedral and the cytoplasm is foamy and eosinophilic.Knowledge Weavers Human Reproduction
1377 Mucinous cystadenomaThese tumors comprise 20% of all neoplasms, and 50% of ovarian neoplasms found in women less than 20 years of age. They are frequently multiloculated. The favored hypothesis for their origin is metaplastic surface epithelium as they have a predominance of endocervical gland type epithelium.Knowledge Weavers Human Reproduction
1378 Ovarian tumorA large vertical incision allows delivery and excision of an ovarian neoplasm. Pelvic washings for cytology and a frozen section rule out a malignancy. The cyst is excised carefully to avoid spilling contents into the abdomen.Knowledge Weavers Human Reproduction
1379 Ultrasound of placental abruptionThe fetal body and bladder are labeled FB, and BL, respectively.Knowledge Weavers Human Reproduction
1380 Uterine ruptureUterine ruptureKnowledge Weavers Human Reproduction
1381 Brenner tumorSolid and partially cystic epithelial nests are surrounded by a stroma composed of bundles of tightly-packed spindle shaped cells. The epithelial cells are polygonal and of the squamoid type, with pale, eosinophilic cytoplasm and oval nuclei having distinct nuclei and longitudinal grooving, a coffee...Knowledge Weavers Human Reproduction
1382 Mucinous cystadenomaThis tumor weighed 35 pounds.Knowledge Weavers Human Reproduction
1383 Brenner tumorBrenner tumors are comprised of solid to partly cystic epithelial nests surrounded by stroma composed of bundles of tightly packed spindle-shaped cells. The epithelial cells are polygonal and of squamoid type, with pale, eosinophilic cytoplasm and oval nuclei with distinct nucleoli and longitudinal ...Knowledge Weavers Human Reproduction
1384 EstradiolThe structure of ethinyl estradiol and mestranol.Knowledge Weavers Human Reproduction
1385 Mucinous cystadenomaNeglected mucinous cystadenoma may become extremely large.Knowledge Weavers Human Reproduction
1386 Mature cystic teratoma - MicroscopicEctodermal tissue is usually most abundant and represented by: squamous epithelium and appendages, brain tissue, glia, retina, choroid plexus, and ganglia. Mesodermal tissue is represented by bone and cartilage. Endodermal tissue is represented by gastrointestinal and bronchial epithelium and glands...Knowledge Weavers Human Reproduction
1387 HirsutismThis woman has polycystic ovarian syndrome and hyperandrogenemia resulting in hirsutism.Knowledge Weavers Human Reproduction
1388 Structures of acetoxy progestins (pregnane steroids)From C. Matthew Peterson, M.D. Progestogens, Progesterone Antagonists, Progesterone, and Androgens: Synthesis, Classification and Uses, Clinical Obstetrics and Gynecology, 1995; 38: 813-20. The structures of acetoxy progestins (pregnane steroids).Knowledge Weavers Human Reproduction
1389 Serous cystadenomaThese tumors comprise 20% of all ovarian neoplasms. The epithelium is a single layer of regular cuboidal epithelium, with basal nuclei and rare mitoses.Knowledge Weavers Human Reproduction
1390 Congenital adrenal hyperplasia and clitoromegalyCongenital adrenal hyperplasia and clitoromegalyKnowledge Weavers Human Reproduction
1391 Mature cystic teratoma-torsed with adenexal structuresElements of all three germ layers are present: endoderm, mesoderm, and ectoderm. They are classified as germ cell tumors and are thought to arise through parthenogenesis. They are found in the path of migration of the germ cells from the yolk sac to the primitive gonad.PathogenesisKnowledge Weavers Human Reproduction
1392 Total placenta previa: placenta accreta in uterine specimenPlacenta accreta or percreta may be associated with placenta previa especially if the patient has had a previous cesarean section.Knowledge Weavers Human Reproduction
1393 Ovarian follicular scanningOvarian follicular scanning. Ovaries are scanned transvaginally to determine the size of the developing follicles.Knowledge Weavers Human Reproduction
1394 Total placenta previa: schematic of complete placenta previaThe placenta completely covers the internal os of the cervix.Knowledge Weavers Human Reproduction
1395 Abruptio placentaAbruptio placentaKnowledge Weavers Human Reproduction
1396 Contraception for women in their later yearsContraception for women in their later reproductive years.Knowledge Weavers Human Reproduction
1397 Pelvic massA pelvic mass may be present with abdominal distention from the mass, ascities, or both.Abdominal DistentionKnowledge Weavers Human Reproduction
1398 Androgen insensitivityAdapted with permission from Jaffe R.B. Disorders of Sexual Differentiation. In Yen SSC and Jaffe RB, eds, Reproductive Endocrinology, W.B. Saunders Co., Philadelphia, 1986, p 300. An inability to respond to testosterone through a target organ receptor defect in 60-70% and a post-receptor signalling...Knowledge Weavers Human Reproduction
1399 Klinefelter's syndromeAdapted with permission from Grumbach M.M. and Conte F.A.,Disorders of Sexual Differentation. In Williams R.H. ed, Textbook of Endocrinology, W. B.Squanders Co., Philadelphia, 1981, p 451. Males with an XXY karyotype characteristically have long extremities, aeunuchoidal habitus, and gynecomastia.Knowledge Weavers Human Reproduction
1400 Polycystic ovariesPolycystic ovary, high power view: Prominent layer of theca interna cells with extensive luteinization. Atretic follicles are more abundant in the cortex.Knowledge Weavers Human Reproduction
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