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Creator | Title | Description | Subject | Date |
| 801 |
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Baehr, Wolfgang; Prestwich, Glenn D. | Photoreceptor cGMP phosphodiesterase delta subunit (PDEdelta) functions as a prenyl-binding protein | Bovine PDEdelta was originally copurified with rod cGMP phosphodiesterase (PDE) and shown to interact with prenylated, carboxymethylated C-terminal Cys residues. Other studies showed that PDEdelta can interact with several small GTPases including Rab13, Ras, Rap, and Rho6, all of which are prenylate... | Fluorescence Resonance Energy Transfer; GTP Phosphohydrolases; Immunohistochemistry | 2004 |
| 802 |
 |
Varner, Michael W. | Physiologic changes in pregnancy: surgical implications. | Pregnancy has measurable effects on essentially every organ system in a woman's body. An understanding of these changes is vital for determining what is normal or abnormal in a pregnant woman. These changes frequently alter symptoms and signs of surgical diseases during pregnancy. In addition, ma... | Pregnancy; Physiologic Changes; Surgical Implications | 1994-06 |
| 803 |
 |
Schmidt, Meic H. | Pigmented villonodular synovitis associated with pathological fracture of the odontoid and atlantoaxial instability | PPigmented villonodular synovitis (PVNS) is a proliferative disorder of the synovium with a predisposition for the appendicular skeleton. Rarely PVNS can arise from the spine, where this disorder usually presents with localized or radicular pain secondary to involvement of the posterior elements. Th... | Atlantoaxial instability; Pigmented villonodular synovitis; Odontoid | 2007 |
| 804 |
 |
Couldwell, William T. | Pituitary apoplexy in the magnetic resonance imaging era: clinical significance of sphenoid sinus mucosal thickening | Object. The authors report their experience with pituitary apoplexy and evaluate the clinical significance of sphenoid sinus mucosal thickening found on magnetic resonance (MR) imaging. Methods. The cases of 28 patients (19 males and nine females) with pituitary apoplexy were reviewed retrospectiv... | | 2006-06 |
| 805 |
 |
Couldwell, William T. | Pituitary apoplexy: diagnosis and management | Pituitary apoplexy, an uncommon complication of pituitary adenomas, was first decribed in 1898 when pearce Bailey reported hemorrhage into a pituitary adenoma in a 50 year old man with acromegaly. The patient presented with sudden onset of headache, nausea, vomiting, fever, oculomotor palsies, and v... | Pituitary Apoplexy; Pituitary adenoma; Transsphenoidal surgery | 2003 |
| 806 |
 |
Couldwell, William T. | Pituitary gland metastasis from adenocarcinoma of the prostate | A case of prostatic carcinoma metastasis to the pituitary gland is reported. The presentation and rarity of such a lesion is addressed. The literature review yielded only isolated case reports of symptomatic brain metastases unassociated with bone disease from adenocarcinoma of the prostate. The man... | Prostate; Pituitary gland; Adenocarcinoma; Metastasis; Transsphenoidal surgery | 1989 |
| 807 |
 |
Couldwell, William T. | Pituitary models | Pituitary tumor animal models provide researchers a microenvironment that simulates the clinical situation; however, in comparison with astrocytoma and meningioma tumor research where intracranial xenograft transplantations are increasingly being used to test various therapeutic modalities, in vivo ... | | 2013-01-01 |
| 808 |
 |
Gardner, Reed M. | The Place of Computers in Medicine (Editorial) | Biomedical Informatics | | 1975 |
| 809 |
 |
Capecchi, Mario R. | Polypeptide chain termination in vitro: isolation of a release factor. | The growing polypeptide chain remains bound to the ribosome-messenger RNA complex through the sRNA carrying the last amino acid incorporated into the polypeptide chain.' On completion of the polypeptide chain a mechanism must exist for releasing it from the protein-synthesizing machinery. To date, m... | Carbon Isotopes; Phenylalanine; Proteins | 1967-09-01 |
| 810 |
 |
Capecchi, Mario R. | Polypetide chain termination. Purification of the release factors, R1 and R2, from Escherichia coli. | We have extensively purified the release factors RI and Rz from Escherichia coli. These proteins can each mediate polypeptide chain termination. The physiological substrate for this reaction is a completed polypeptide chain in a peptidyl- transfer RNA-messenger RNA-ribosome complex. The reaction con... | Acrylates; Detergents | 1971-02-25 |
| 811 |
 |
Varner, Michael W.; Cannon, Cynthia; Ward, Robert | Population-based study of congenital diaphragmatic hernia in Utah: 1988-1994. | OBJECTIVE: To define the natural history of congenital diaphragmatic hernia and to determine the potential impact of fetal therapy. METHODS: This retrospective case series consisted of all fetuses and neonates with congenital diaphragmatic hernia born between 1988 and 1994 in the state of Utah that ... | Hernia, Diaphragmatic; Fetal Diseases; Prenatal Diagnosis; Utah/epidemiology | 1996-06 |
| 812 |
 |
Couldwell, William T. | Porous polyethylene implant for cranioplasty and skull base reconstruction | Object. Cranial reconstruction after skull base surgery is important for restoration of function and cosmesis. The authors describe their experience with the Medpor porous polyethylene implant for cosmetic cranioplasty and reconstruction after skull base surgery. Methods. Medpor, a biocompatible i... | | 2004 |
| 813 |
 |
Couldwell, William T. | Posterior fossa brain tumors and arterial hypertension | Hypertension caused by arterial compression of the rostral ventrolateral medulla is well described. Much less information is available on the association between neurogenic hypertension and posterior fossa brain tumors. To date, multiple reports have supported the impression that a small subpopulat... | Posterior fossa tumors; Brain stem; Arterial hypertension; Essential hypertension; EHTN | 2006 |
| 814 |
 |
Couldwell, William T. | Posterolateral approach for decompression with anterior and posterior fusion: a less invasive surgical technique for stabilization of the thoracic spine | The goals of surgery in unstable thoracic fractures or tumors involving the thoracic spine are neural decompression, correction of deformity, and stabilization. Several different approaches can be used to achieve these goals. The anterior, combined anterior and posterior, and more recently thoraco... | Decompression; Thoracic spine; Posterolateral approach | 1998 |
| 815 |
 |
Olson, Randall J.; Mamalis, Nick; Spencer, Terrence S. | Postoperative sterile endophthalmitis (TASS) associated with the memorylens | PURPOSE: To report 10 cases of delayed-onset acute intraocular inflammation following cataract extraction and posterior chamber implantation of the MemoryLens(R) intraocular lens (IOL). SETTING: John A. Moran Eye Center, Department of Ophthalmology, University of Utah, Salt Lake City, Utah, USA. MET... | Memory Lens; Toxic Anterior Segment Syndrome; Retrospective Studies; adverse effects | 2000-12 |
| 816 |
 |
Kestle, John R. W. | Potentially useful outcome measures for clinical research in pediatric neurosurgery | The choice of outcome (or outcomes) and their measurement are critical for a sound clinical trial. Surgeons have traditionally measured simple outcomes such as death, duration of survival, or tumor recurrence but have recently developed more sophisticated measures of the effect of an intervention. M... | Pediatric neurosurgery | 2005 |
| 817 |
 |
Couldwell, William T. | Practicing neurosurgery in the United States | Compared with other developed countries, the U.S. spends a high percentage of its gross domestic product on healthcare: 16 percent in 2005, up from 15 percent in 2004. This is far and away the greatest percentage of GDP spent on healthcare of any nation for which such data is collected. However,... | | 2008-01-01 |
| 818 |
 |
Lam, LeAnn | Pre-clinical animal model for ovarian cancer using live imaging system | Development of a live imaging animal model for orthotopic ovarian cancers in order to better understand disease mechanisms and response to potential anticancer drug treatments. | Ovarian cancer; Cancer; Animal model; Live imaging; Cell culture; ACCESS | 2015-04-14 |
| 819 |
 |
Mitchell, Joyce A. | Predicting phenotypic severity of uncertain gene variants in the RET Proto-Oncogene | Although reported gene variants in the RET oncogene have been directly associated with multiple endocrine neoplasia type 2 and hereditary medullary thyroid carcinoma, other mutations are classified as variants of uncertain significance (VUS) until the associated clinical phenotype is made clear. Cur... | | 2011-01-01 |
| 820 |
 |
Kestle, John R. W. | Predicting shunt failure on the basis of clinical symptoms and signs in children | Object. In evaluating pediatric patients for shunt malfunction, predictive values for symptoms and signs are important in deciding which patients should undergo an imaging study, whereas determining clinical findings that correlate with a low probability of shunt failure could simplify management. ... | Pediatric Shunt Design Trial; PSDT; Shunt failure; Shunt malfunction; Clinical signs | 2001 |
| 821 |
 |
Kestle, John R. W. | Predicting slitlike ventricles in children on the basis of baseline characteristics at the time of shunt insertion | Object. Slit ventricle syndrome (SVS) is a delayed complication of shunt insertion and occurs only in children with slitlike ventricles after shunt placement. Although SVS appears to be related to early shunt placement, its predisposing factors are largely unknown. Methods. Baseline data in 737 chi... | Slitlike ventricles; Slit ventricle syndrome; Shunt insertion; Predictive factor; Ventriculoperitoneal shunt; Pediatric neurosurgery | 2007 |
| 822 |
 |
Couldwell, William T. | Predictive value of serum prolactin levels measured immediately after transsphenoidal surgery | Object. Prolactin-secreting pituitary adenomas may be managed by surgery, medication, radiotherapy, or observation. The authors reviewed a consecutive series of patients who were followed for at least 5 years after surgery to assess the prognostic significance of preoperative factors (tumor size and... | Prolactin; Transsphenoidal surgery; Pituitary adenoma; Prolactinoma; Transsphenoidal approach | 2002 |
| 823 |
 |
Sung, Younghoon; Renshaw, Perry Franklin | Prefrontal grey-matter changes in short-term and long-term abstinent methamphetamine abusers | Author's explored grey-matter density in 29 methamphetamine abusers and 20 healthy comparison subjects using voxel-based morphometry. Grey-matter density changes and performances on the Wisconsin Card Sorting test (WCST) were also compared between 11 short-term (<6 months) and 18 long-term (o6 mon... | | 2006 |
| 824 |
 |
Mitchell, Joyce A. | Preliminary evaluation of learning via the AI/LEARN/Rheumatology interactive videodisc system | AI/LEARN/Rheumatology is a level three videodisc system to teach clinical observational skills in three important diseases: rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. The AI/LEARN software was developed on an independent authoring system called GALE designed for MS-DOS based c... | | 1992-01-01 |
| 825 |
 |
Frederick, Jeanne M. | The prenyl-binding protein PrBP/δ: A chaperone participating in intracellular trafficking | Expressed ubiquitously, PrBP/d functions as chaperone/co-factor in the transport of a subset of prenylated proteins. PrBP/d features an immunoglobulin-like b-sandwich fold for lipid binding, and interacts with diverse partners. PrBP/d binds both C-terminal C15 and C20 prenyl side chains of phototran... | | 2012-01-01 |
