Filters: School Or College: "School of Medicine" Department: "Neurology" Collection: "ir_uspace" Format: "application/pdf"
| Creator | Title | Description | Subject | Date | ||
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Foster, Norman L. | Justifying reimbursement for Alzheimers diagnostics and treatments: Seeking alignment on evidence | The increasing cost of health care combined with expensive new drugs and diagnostics is leading to more frequent gaps between regulatory and reimbursement approval decisions. As a result, persons with Alzheimer's disease may have difficulty accessing the benefits of medical advances. In contrast to ... | 2014-01-01 | |
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Agarwal, Nivedita | Microstructural thalamic changes in schizophrenia: a combined anatomic and diffusion weighted magnetic resonance imaging study | Objective: Several magnetic resonance imaging (MRI) and postmortem studies have supported the role of the thalamus in the pathophysiology of schizophrenia. Interestingly, a recent small diffusion weighted imaging (DWI) study showed abnormal thalamic microstructure in patients with schizophrenia. The... | 2008-01-01 | |
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Digre, Kathleen B.; Couldwell, William T.; Amini, Amin | Photophobia in a blind patient: An alternate visual pathway. Case report. | Photophobia is a common neurological and ophthalmological symptom that has been associated with a growing number of neurosurgical conditions, especially compressive lesions. The exact signaling pathways and neurophysiological features of the disorder are not well understood; however, data from multi... | Photophobia, Blindness, Signaling Pathway, Pretectal Nuclei, Trigeminal Pathway | 2006-12-14 |
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Agarwal, Nivedita | Brain function monitoring during off-pump cardiac surgery: a case report | Background: Early postoperative stroke is an adverse syndrome after coronary bypass surgery. This report focuses on overcoming of cerebral ischemia as a result of haemodynamic instability during heart enucleation in off-pump procedure. Case presentation: A 67 year old male patient, Caucasian race, ... | 2008 | |
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Digre, Kathleen B.; Warner, Judith E. A.; Bernstein, Paul S.; Alder, Stephen C. | Vitamin A in the cerebrospinal fluid of patients with and without idiopathic intracranial hypertension | We quantified vitamin A in the cerebrospinal fluid of patients with idiopathic intracranial hypertension, elevated intracranial pressure of other causes and normal intracranial pressure. Vitamin A could be detected by high-pressure liquid chromatography in most of the specimens. There was a signific... | Chromatography, High Pressure Liquid; Headache | 2002-11 |
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Digre, Kathleen B. | Serum vitamin A concentration is elevated in idiopathic intracranial hypertension. | OBJECTIVE: The primary purpose was to investigate whether serum vitamin A concentration is associated with idiopathic intracranial hypertension (IIH). The secondary aim was to obtain pilot data regarding the amount of vitamin A ingested by patients and controls. BACKGROUND: Vitamin A is an attractiv... | Vitamin A; Retinol; Idiopathic intracranial hypertension; Chromatography | 2007-02-01 |
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Digre, Kathleen B. | Selective MR imaging approach for evaluation of patients with Horner's syndrome. | PURPOSE: To assess the usefulness of MR in the evaluation of patients with Horner's syndrome. PATIENTS AND METHODS: We prospectively performed MR imaging in 33 patients with Horner's syndrome (13 preganglionic and 20 postganglionic) using a protocol specifically designed for pre- and postganglionic ... | Horner Syndrome; Magnetic Resonance Imaging; Epidemiology | 1992-01 |
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Kriesel, John D.; Maulden, Sarah Annamarie; Spruance, Spotswood L. | Anti-interleukin-6 antibodies inhibit herpes simplex virus reactivation. | Herpes simplex viruses (HSVs) infect epithelial cells, become localized in neurons, and can reactivate in response to a variety of stimuli, including ultraviolet light and hyperthermia. The sequence of gene activation during viral replication is known, but the molecular linkage between exogenous sti... | Mice, Inbred BALB C; Tumor Necrosis Factor-alpha; Virus Activation | 1997 |
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Digre, Kathleen B.; Blumenthal, Deborah T.; Salzman, Karen L.; Jensen, Randy L.; Dunson, William A. | Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis. | A 67-year-old man sequentially developed anti-Ma2-associated paraneoplastic encephalitis (PNE) and contralateral herpes simplex encephalitis (HSE). Brain biopsy 1 month before HSE revealed extensive infiltrates of T cells, B cells, and plasma cells. Most T cells expressed the cytotoxic granule-assoc... | Paraneoplastic neurologic disorders; Encephalitis; Neoplasm;Herpes Simplex | 2006-07-11 |
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Rodin, Ernst A. | Interictal infraslow activity in patients with epilepsy | Objective: To evaluate if interictal infraslow activity (ISA), as obtained from a conventional EEG system, can contribute information about the epileptogenic process. Methods: The entire long-term intracranial monitoring sessions of 12 consecutive patients were evaluated on an XLTEK system for ISA. ... | 2014-01-01 | |
| 11 |
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Digre, Kathleen B.; Schmidt, Richard H.; Osborne, Anne G.; Patel, Bhupendra C.; Pratt, David; Rietz, Lisa A. | Compressive optic neuropathy caused by renal osteodystrophy. Case report. | Compressive optic neuropathy with acute or chronic vision loss has been associated with various skull base tumors, aneurysms, Graves disease, trauma, and, less commonly, fibrous dysplasia and osteopetrosis. The Author's present a case of acute visual deterioration in a 25-year-old woman who had mass... | Optic Neuropathy; Optic Nerve Decompression; Renal Osteodystrophy | 2001-10 |
| 12 |
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Digre, Kathleen B.; Mamalis, Nick; White, George L. Jr. | Congenital anomalies of the optic nerve in one family. | We present three cases of congenital optic disc anomalies in one family who underwent an extensive diagnostic workup to exclude any intracranial pathology. One patient had elevated optic nerve heads and was hospitalized for multiple diagnostic tests including a lumbar puncture and magnetic resonance... | Optic Nerve; Congenital Anomalies | 1992-04-24 |
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Digre, Kathleen B. | CT and hemifacial spasm. | Forty-six patients with typical hemifacial spasm had CT. Thirty-eight (83%) were abnormal, including two with surgically documented tumors. Thirty-six had a characteristic dolichoectatic vertebrobasilar artery, with the convexity pointing to the side of the spasm in 92% of the scans. This study sugg... | Hemifacial spasms; Tumors; Dolichoectiatic vertebrobasilar artery | 1988-07 |
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Bernstein, Paul S.; Leppert, Mark F. | Genotype-phenotype analysis of ABCR variants in macular degeneration probands and siblings | PURPOSE: Single-copy variants of the autosomal recessive Stargardt disease (STGD1) gene ABCR (ABCA4) have been shown to confer enhanced susceptibility to age-related macular degeneration (AMD). To investigate the role of ABCR alleles in AMD further, genotype-phenotype analysis was performed on sibli... | DNA Mutational Analysis; Nuclear Family; Phenotype | 2002 |
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Kriesel, John D.; Baringer, J R; Spruance, Spotswood L. | Correlation between detection of herpes simplex virus in oral secretions by PCR and susceptibility to experimental UV radiation-induced herpes labialis. | We examined the oral secretions of 25 patients for herpes simplex virus (HSV) at the time of and following experimental UV radiation (UVR). HSV was detected in one or more oral secretion specimens in 5 of 12 (42%) cases by cell culture and in 8 of 12 (67%) cases by PCR. On the day of UVR, HSV was de... | Polymerase Chain Reaction; Ultraviolet Rays; Simplexvirus | 1994 |
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Digre, Kathleen B.; Skuster, Denise Z. | Neurologic conditions presenting as psychiatric disorders. | Understanding underlying neuroanatomic function helps physicians to localize defects and search for treatable neurologic conditions. Neurologic conditions such as Huntington's chorea, Wilson's disease, Gille de la Tourette syndrome, brain tumors, encephalitis and meningitis, neurodegenerative condit... | Psychiatric Diagnosis; Neurologic Disease | 1992-06-15 |
| 17 |
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Digre, Kathleen B. | Significance of CT and MR findings in sphenoid sinus disease. | Disorders of the paranasal sinuses, particularly the sphenoid sinus, can be associated with significant disorders of the optic and other cranial nerves. We examined 100 consecutive routine CT scans, 100 posterior fossa CT scans, and 100 MR scans to look for evidence of sinus disease, especially of t... | Sphenoid Sinus; Vision Disorders; Paranasal Sinus Diseases; Magnetic Resonance Imaging | 1989-05 |
| 18 |
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Jaeckle, Kurt A.; Digre, Kathleen B.; Jones, Christopher R.; Bailey, Peter L. | Central neurogenic hyperventilation: pharmacologic intervention with morphine sulfate and correlative analysis of respiratory, sleep, and ocular motor dysfunction. | Central neurogenic hyperventilation (CNH), for which there is no effective therapy, can eventually result in respiratory fatigue and death. This report describes a patient with CNH due to a brainstem anaplastic astrocytoma who also exhibited disturbances of sleep and ocular motor function. The CNH r... | Central Neurogenic H yperventilation; Ocular Motor Dysfunction | 1990-11 |
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Jones, Bryan W.; Jones, Christopher R.; Czajkowski, Laura | Familial advanced sleep-phase syndrome: a short-period circadian rhythmvariant in humans | Biological circadian clocks oscillate with an approximately 24-hour period, are ubiquitous, and presumably confer a selective advantage by anticipating the transitions between day and night. The circadian rhythms of sleep, melatonin secretion and body core temperature are thought to be generated by ... | Activity Cycles; Matched-Pair Analysis; Polysomnography | 1999 |
| 20 |
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Levy, James A. | Context-specific memory and apolipoprotein E (ApoE) epsilon 4: cognitive evidence from the NIMH prospective study of risk for Alzheimer's disease. | The aim of the study was to determine whether the epsilon 4 allele of the apolipoprotein E (ApoE) gene was associated primarily with context-specific memory among individuals at genetic risk for developing Alzheimer's disease. The effect of ApoE status on comprehensive neuropsychological results was... | Alleles; Apolipoprotein E4; Mental Status Schedule | 2004-05-10 |
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Varner, Michael W.; Digre, Kathleen B. | Cranial magnetic resonance imaging in eclampsia. | Although the precise neuropathologic basis for eclamptic convulsions remains unclear, intracranial hemorrhage is frequently associated with fatal cases. Magnetic resonance imaging (MRI) is a recently developed neuroimaging technique that appears superior to other processes for defining intracranial ... | Eclampsia; Brain Edema; Cranial Magnetic Resonance Imaging | 1987-09 |
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Rodin, Ernst A. | Prognosis of Patients with Epilepsy | |||
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Digre, Kathleen B. | Novel mechanism for benign essential blepharospasm. | PURPOSE: The purpose of this study is to test the hypothesis that the photophobia of benign essential blepharospasm (BEB) is caused by sympathetically maintained pain. METHODS: Nineteen patients with photophobia and BEB were enrolled in an unblinded prospective treatment trial. The intervention was ... | Blepharospasm, Autonomic Nerve Block, Blepharospasm, Superior Cervical Ganglion, Lidocaine, Pain | 1999-11-15 |
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Rodin, Ernst A. | Prognosis of Patients with Epilepsy | Written primarily for the physician who is responsible for the treatment of epileptic patients and the clinical investigator interested in the basic mechanisms underlying this disorder. The book also addresses itself to psychologists interested in the study of mind-brain relationships. Factors relat... | epilepsy; epileptic patients; mind-brain relationships | 1968 |
| 25 |
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Digre, Kathleen B.; Blumenthal, Deborah T.; Salzman, Karen L.; Jensen, Randy L.; Dunson, William A. | Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis. | A 67-year-old man sequentially developed anti-Ma2-associated paraneoplastic encephalitis (PNE) and contralateral herpes simplex encephalitis (HSE). Brain biopsy 1 month before HSE revealed extensive infiltrates of T cells, B cells, and plasma cells. Most T cells expressed the cytotoxic granule-assoc... | Paraneoplastic neurologic disorders; Encephalitis; Neoplasm;Herpes Simplex | 2006-07-11 |