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1Blumenthal, Donald K.Ranolazine: a new antianginal agent with a novel mechanism of actionThis animation (with audio) illustrates the mechanism of action of ranolazine (RANEXA), a novel antianginal drug that inhibits the late sodium current (late I Na) in cardiac myocytes. The animation first describes how the late sodium current can contribute to symptoms of myocardial ischemia by causi...Angina; Myocardial Ischemia, Acute Coronary Syndrome; Voltage-Gated Sodium Channel, Late Sodium Current; Sodium-Calcium Exchanger; Calcium Overload; Ranolazine2006-09-19
2Blumenthal, Donald K.Structure of vardenafil in the active site of PDE5PyMol file (725 KB): http://ir.utah.edu/blumenthal/PyMol/PDE5_Vardenafil.pse Download PyMol software to view this file. Available for free educational use: http://pymol.sourceforge.net Quicktime Movie--High Resolution (4 MB): http://stream.lib.utah.edu/index.php?c=details&id=9288 Quicktime Movie--...Levitra; Phosphodiesterase inhibitors; PDE; Enzymes; Intracellular cyclic nucleotide-mediated signaling; 1106342006-07-14
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