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TitleCreatorDescriptionSubjectImaging
1 How Mitochondria Orchestrate the Death of RGCs : From Brazil to Tuebingen to Rochester 2007Alfredo A. Sadun, MD, PhDSlides showing LHON and Kjer's optic atrophy and images of optic disk with LHON. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia; Blindness.Optic Nerve; Retina; Retinal Ganglion Cells; Reactive Oxygen Species; Scotoma; Telangiectasis; Apoptosis; Cell Death; Dyschromatopsia; Blindness; Optic Atrophy; Hereditary; Leber; Leber's Optic Neuropathy
2 Mitochondria and the RGCAlfredo A. Sadun, MD, PhDDiscussion of various forms of mitrochondrial optic neuropathies and how to distinguish from toxic optic neuropathies, with examples from Cuba and Brazil. Presenting Symptom: Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia. Anatomy: Optic nerve; Optic disc; Retinal ganglion cells; Reactive oxyge...Optic Nerve; Optic Disc; Retinal Ganglion Cells; Reactive Oxygen Species; Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia; Optic Atrophy; Autosomal Dominant; Optic Atrophy; Hereditary; Leber; Toxic Optic Neuropathy; Brazil; Cuba; Linezolid
3 Toxic Optic Neuropathies: How Much Evidence Should it Take to Convict?Alfredo A. Sadun, MD, PhDA critique of claims that the drug Amiodarone causes optic neuropathies. Presenting Symptom: Scotoma; Dyschromatopsia. Anatomy: Optic nerve. Disease/Diagnosis: Toxic optic neuropathy.Amiodarone; Linezolid; Scotoma; Dyschromatopsia; Toxic Optic Neuropathy
4 Viagra and Vision Loss: Does Sex Make You Blind?Alfredo A. Sadun, MD, PhDAt a formal debate during a meeting in Canada in Sept. 2006, Sadun was assigned the role of arguing the case FOR a connection between taking phosphodiesterase 5 (PDE5) inhibitors and developing anterior ischemic optic neuropathy. Presenting Symptom: Hypotension. Anatomy: Optic nerve; Optic disc; Cyc...Sildenafil; Vardenafil; Tadalafil; Viagra; Levitra; Cialis; Optic Neuropathy, Ischemic; Toxic Optic Neuropathy; Optic Nerve; Optic Disc; Cyclic Nucleotide Phosphodiesterases, Type 5; Hypotension
5 Viagra and Vision Loss: Does Sex Make You Blind?Alfredo A. Sadun, MD, PhDPresenting symptom: Hypotension. Anatomy: Optic nerve; Optic disc; Cyclic Nucleotide Phosphodiesterases, Type 5. Disease/Diagnosis: Optic Neuropathy, Ischemic; Toxic optic neuropathy.Sildenafil; Vardenafil; Tadalafil; Viagra; Levitra; Cialis; Optic Neuropathy, Ischemic; Toxic Optic Neuropathy; Optic Nerve; Optic Disc; Cyclic Nucleotide Phosphodiesterases, Type 5; Hypotension
6 The Neuro-Ophthalmic Manifestations of DiabetesAlfredo A. Sadun, MD, PhDAnatomy: Orbit; Optic nerve. Disease/Diagnosis: Diabetes; Mucormycosis; Acidosis; Hypoplasia of the optic nerve; Diabetes mellitus; Diabetic optic papillopathy; Optic neuropathy, Ischemic; Diabetic optic atrophy; Ophthalmoplegia; Arteritis; Diabetic ketoacidosis; Orbital cellulitis. Treatment: Debri...Diabetes; Mucormycosis; Acidosis; Hypoplasia of the Optic Nerve; Diabetes Mellitus; Diabetic Optic Papillopathy; Optic Neuropathy, Ischemic; Diabetic Optic Atrophy; Ophthalmoplegia; Arteritis; Diabetic Ketoacidosis; Orbital Cellulitis; Hyphae; Orbit; Optic Nerve; Debridement
7 Optic Nerve Sheath Decompression in the Management of Optic NeuropathiesAlfredo A. Sadun, MD, PhDA slide presentation with several images of optic disc, normal and with edema. Anatomy: Optic nerve; Optic disc. Disease/Diagnosis: Optic neuropathy, Ischemic; Pseudotumor cerebri; Papilledema. Treatment: Decompression, Surgical.Decompression, Surgical; Optic Neuropathy, Ischemic; Pseudotumor Cerebri; Papilledema; Optic Nerve; Optic Disc
8 The Diagnostic Workup in Patients With Optic Neuropathies (Metodo diagnostico)Alfredo A. Sadun, MD, PhDSlideshow presentation with images of optic disc with edema and "Positive temporal artery biopsy". Presenting Symptom: Hyperopia; Metamorphopsia. Anatomy: Optic nerve; Macula Lutea; Optic disc. Disease/Diagnosis: Optic neuritis; Macular edema; Optic neuropathy, Ischemic.Hyperopia; Metamorphopsia; Optic Nerve; Macula Lutea; Optic Disc; Optic Neuritis; Macular Edema; Optic Neuropathy, Ischemic
9 The Clinical Spectrum of Amiodarone-Associated Optic NeuropathyAlfredo A. Sadun, MD, PhDSadun's response to a paper by L.N. Johnson, G.B. Kroheld, and E.R. Thomas at 2004 AAO meeting. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Optic neuropathy, IschemicAmiodarone; Optic Neuropathy, Ischemic
10 How Strong is the Case for an Association Between PDE5 Inhibitors and NAION?Alfredo A. Sadun, MD, PhDAnatomy: Optic nerve. Disease/Diagnosis: Optic Neuropathy, Ischemic; Toxic optic neuropathy. Presenting Symptom: Ischemia; Scotoma; Dyschromatopsia.Optic Neuropathy, Ischemic; Toxic Optic Neuropathy; Ischemia; Scotoma; Dyschromatopsia; Optic Nerve; Phosphodiesterase 5 Inhibitor; Viagra
11 Toxic Optic Neuropathies: Mitochondria and the RGCAlfredo A. Sadun, MD, PhDDiscussion of various forms of mitrochondrial optic neuropathies and how to distinguish from toxic optic neuropathies, with examples from Cuba and Brazil; includes images of optic disc showing LHON. Presenting Symptom: Blindness; Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia. Anatomy: Optic ne...Optic Nerve; Optic Disc; Retinal Ganglion Cells; Reactive Oxygen Species; Blindness; Scotoma; Telangiectasis; Apoptosis; Dyschromatopsia; Optic Atrophy, Autosomal Dominant; Optic Atrophy, Hereditary, Leber; Toxic Optic Neuropathy; Alcoholic Neuropathy; Brazil; Cuba; Linezolid; Ethambutol; Tomography...
12 Acute Retrobulbar Optical NeuropathyAlfredo A. Sadun, MD, PhDPPT covering acute retrobulbar optic neuropathy, including ischemic, inflammatory, anterior ischemic optic neuropathy (AION) and non-arteritic anterior ischemic optic neuropathy (NAION); includes brainscan images for optic neuritis and multiple sclerosis; optic disk with LHON and PION. Anatomy: Opt...Optic Neuropathy, Ischemic; Giant Cell Arteritis; Edema; Multiple Sclerosis; Optic Atrophy, Hereditary, Leber; Ischemia; Hypotension; Edema; Optic Neuritis; Optic Nerve; Interferon-Beta-1a; Diseases of the Optic Nerve
13 Atypical Optic NeuropathiesAlfredo A. Sadun, MD, PhDA discussion of atypical optic neuropathies. Anatomy: Optic nerve; Optic disc. Pathology: Slides showing LHON. Disease/Diagnosis: Optic neuropathy, Ischemic; Optic atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Optic neuritis; Eye hemorrhage; Retinal vasculitis; Dyschromatop...Brazil; Cuba; Ethambutol; Optic Neuritis; Eye Hemorrhage; Retinal Vasculitis; Dyschromatopsia; Scotoma; Ataxia; Paresthesia; Hyporeflexia; Optic Nerve; Optic Disc; Optic Neuropathy, Ischemic; Optic Atrophy, Hereditary, Leber; Toxic Optic Neuropathy
14 Mitochondrial Optic Neuropathy: Mitochondria as Gatekeepers for ApoptosisAlfredo A. Sadun, MD, PhDAnatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Scotoma; Dyschromatopsia.Apoptosis; Cell Death; Optic Atrophy, Hereditary, Leber; Toxic Optic Neuropathy; Optic Nerve; Retina; Retinal Ganglion Cells; Reactive Oxygen Species; Amiodarone; Scotoma; Dyschromatopsia
15 Posterior Ischemic Optic NeuropathyAlfredo A. Sadun, MD, PhDDiscusses opthalmic complications of surgery, with example of shock-induced Posterior Ischemic Optic Neuropathy following a hysterectomy. Presenting Symptom: Ischemia; Hypotension. Anatomy: Optic nerve. Disease/Diagnosis: Optic neuropathy, Ischemic; Hematoma; Edema.Optic Neuropathy, Ischemic; Hematoma; Edema; Ischemia; Hypotension; Optic Nerve; Posterior Ischemic Optic Neuropathy
16 Pupils and the Neuro-Ophthalmic Manifestations of DiabetesAlfredo A. Sadun, MD, PhDPresentation given in Italy on diagnosing neuro-opthalmic complications of diabetes with several views of the optic disc. Presenting symptom: Diplopia; Anisocoria; Ptosis; Horner syndrome; Adie syndrome. Anatomy: Pupil; Optic disc; Optic nerve. Disease/Diagnosis: Diabetes; Mucormycosis; Acidosis; Hy...Pupil; Optic Disc; Optic Nerve; Diplopia; Anisocoria; Ptosis; Horner Syndrome; Adie Syndrome; Diabetes; Mucormycosis; Acidosis; Hypoplasia of the Optic Nerve; Diabetes Mellitus; Diabetic Optic Papillopathy; Optic Neuropathy, Ischemic; Diabetic Optic Atrophy; Ophthalmoplegia; Diabetic Ketoacidosis; D...
17 The Diagnostic Workup in Patients With Optic NeuropathiesAlfredo A. Sadun, MD, PhDSlideshow presentation with images of optic disc with edema and optic atrophy. Presenting Symptom: Telangiectasis; Dyschromatopsia; Scotoma. Anatomy: Optic nerve; Optic disc; Phosphopyruvate Hydratase; Enolase. Disease/Diagnosis: Optic neuritis; Macular edema; Optic neuropathy, Ischemic; Optic atrop...Telangiectasis; Dyschromatopsia; Scotoma; Optic Nerve; Optic Disc; Phosphopyruvate Hydratase; Enolase; Optic Neuritis; Macular Edema; Optic Neuropathy, Ischemic; Optic Atrophy, Hereditary
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