| | Title | Creator | Description | Subject | Date |
|---|
| 1 |  | Senior-Løken syndrome: a syndromic form of retinal dystrophy associated with nephronophthisis | Bernstein, Paul S. | Senior-Løken syndrome (SLS) is an autosomal recessive disease characterized by development of a retinitis (RP)- or Leber congenital amaurosis (LCA)-like retinal dystrophy and a medullary cystic kidney disease, nephronophthisis. Mutations in several genes (called nephrocystins) have been shown to ca... | | 2012-01-01 |
| 2 |  | Raman detection of macular carotenoid pigments in intact human retina | Bernstein, Paul S.; Gellermann, Werner | PURPOSE: To develop and test a novel noninvasive optical technique suitable for the objective measurement of macular carotenoid levels in human retina. METHODS: A resonance Raman scattering apparatus was constructed to measure carotenoid levels in flat-mounted human retinas and eyecups and in experi... | Rana pipiens; Spectrum Analysis, Raman; Xanthophylls | 1998 |
| 3 |  | CT and hemifacial spasm. | Digre, Kathleen B. | Forty-six patients with typical hemifacial spasm had CT. Thirty-eight (83%) were abnormal, including two with surgically documented tumors. Thirty-six had a characteristic dolichoectatic vertebrobasilar artery, with the convexity pointing to the side of the spasm in 92% of the scans. This study sugg... | Hemifacial spasms; Tumors; Dolichoectiatic vertebrobasilar artery | 1988-07 |
| 4 |  | Sedimentation field-flow fractionation: a method for studying particulates in cataractous lens | Olson, Randall J.; Coldwell, Karin D.; Compton, Bruce J.; Giddings, John C. | It is shown that the technique of sedimentation field-flow fractionation (sedimentation [sed] FFF) can be used to determine the particle content and particle size distribution of normal and cataractous lenses. A 31-year-old normal human lens, for example, showed a particle content of 1.5% by weight ... | Fractionation; Cataractous Lens; Particulates | 1984 |
| 5 |  | Silicon-based, three-dimensional neural interface: manufacturing processes for an intracortical electrode array | Normann, Richard A.; Campbell, Patrick K.; Jones, Kelly E.; Huber, Robert J.; Horch, Kenneth W. | A method has been developed for the manufacture of a "three-dimensional" electrode array geometry for chronic intracortical stimulation. This silicon based array consists of a 4.2 x 4.2 x 0.12 mm thick monocrystalline substrate, from which project 100 conductive, silicon needles sharpened to facilit... | Electric Stimulation; Electrodes, Implanted; Sensory Cortex; Intracortical Electrode Array | 1991 |
| 6 |  | Mobility performance with a pixelized vision system | Normann, Richard A.; Horch, Kenneth W.; Cha, Kichul | A visual prosthesis, based on electrical stimulation of the visual cortex, has been suggested as a means for partially restoring functional vision in the blind. The prosthesis would create a pixelized visual sense consisting of punctate spots of light (phosphenes). The present study investigated the... | Visual Prosthesis; Mobility; Phosphene Simulator | 1992 |
| 7 |  | Signal integration at the pedicle of turtle cone photoreceptors: an anatomical and electrophysiological study | Normann, Richard A.; Kolb, Helga; Lasater, Eric M. | The morphology of the axon which connects the cell body and pedicle of turtle cone photoreceptors was studied by light and electron microscopy. The axon which contains numerous synaptic vesicles, some endoplasmic reticulum, and a few cisternae is basically filled with cytoplasm. The length of the ax... | Cone Photoreceptor, Voltage Clamp; Isolated Cells; Input Resistance; Cell Body-Pedicle Coupling | 1989 |
| 8 |  | Functional reorganization of primary visual cortex induced by electrical stimulation in the cat. | Normann, Richard A. | Compared to the high degree of plasticity observed in a juvenile, mature sensory cortices have long been held to be immutable but, recently, researchers have suggested some plasticity persists in the mature cortex. Cortical reorganization has particular saliency to the development of a cortically ba... | Cat; Electrophysiology; Phosphene; Plasticity; Receptive Field; Striate Cortex | 2005 |
| 9 |  | Encoding mechanisms for sensory neurons studied with a multielectrode array in the cat dorsal root ganglion | Normann, Richard A.; Shoham, Shy | Recent advances in microelectrode array technology now permit a direct examination of the way populations of sensory neurons encode information about a limb's position in space. To address this issue, we recorded nerve impulses from about 100 single units simultaneously in the L6 and L7 dorsal root ... | Sensory; Encoding; Multielectrode; Dorsal Root Ganglion; Cutaneour; Muscle | 2004 |
| 10 |  | Three-dimensional architecture for a parallel processing photosensing array | Normann, Richard A.; Johansson,Torbjorn; Abbasi, Masoud; Huber, Robert J. | A three-dimensional architecture for a photosensing array has been developed. This silicon based architecture consists of a 10 x 10 array of photosensors with 80 microns diameter, through chip interconnects to the back side of a 500 microns thick silicon wafer. Each photosensor consists of a 300 x 3... | Retina; Optics; Silicon; Photosensing | 1992 |
| 11 |  | Neural interface for a cortical vision prosthesis | Normann, Richard A.; Maynard, Edwin M. | The development of a cortically based vision prosthesis has been hampered by a lack of basic experiments on phosphene psychophysics. This basic research has been hampered by the lack of a means to safely stimulate large numbers of cortical neurons. Recently, a number of laboratories have developed a... | Neuroprosthetics; Artificial Vision; Electrode Arrays; Multielectrode Recordings; Biocompatibility | 1999 |
| 12 |  | Selective motor unit recruitment via intrafascicular multielectrode stimulation | Normann, Richard A.; Clark, Gregory A.; McDonnall, Daniel | Recruitment of force via independent asynchronous firing of large numbers of motor units produces the grace and endurance of physiological motion. We have investigated the possibility of reproducing this physiological recruitment strategy by determining the selectivity of access to large numbers of ... | Funtional Neuromuscular Stimulation; Microelectrode Array; Neuroprosthesis; Intrafascicular Multielectrode Stimulation; Cats | 2004 |
| 13 |  | Effects of GABA and related drugs on horizontal cells in the isolated turtle retina | Normann, Richard A. | The role of GABA in the outer plexiform layer of the turtle retina has been examined by intracellular recordings from L- and C-type horizontal cells in the isolated retina preparation. GABA (1-5 mM) slightly depolarized the L-type horizontal cells, reduced the amplitude of their photoresponses, and ... | Retina; Horizontal Cells; Synapse; Negative Feedback; GABA; Turtle | 1990 |
| 14 |  | Nonmydriatic fluorescence-based quantitative imaging of human macular pigment distributions. | Bernstein, Paul S.; Gellermann, Werner | We have developed a CCD-camera-based nonmydriatic instrument that detects fluorescence from retinal lipofuscin chromophores ("autofluorescence") as a means to indirectly quantify and spatially image the distribution of macular pigment (MP). The lipofuscin fluorescence intensity is reduced at all ret... | Cytology; Sensitivity and Specificity | 2006-10 |
| 15 |  | HPLC measurement of ocular carotenoid levels in human donor eyes in the lutein supplementation era. | Bernstein, Paul S. | PURPOSE: A substantial proportion of the population at risk for visual loss from age-related macular degeneration consumes supplements containing high doses of lutein, but clinical studies to date have shown only modest and variable increases in macular carotenoid pigments in response to supplementa... | Chromatography, High Pressure Liquid; Dietary Supplements; Tissue Donors | 2007-02 |
| 16 |  | Serum and macular responses to antioxidant supplementation verus a carotenoid-rich dietary intervention in the elderly. | Askew, Eldon W.; Bernstein, Paul S. | The aim of this study was to observe responses of serum antioxidants, oxidative stress biomarkers, and macular carotenoid pigments to antioxidant supplements or dietary intervention in a single-masked, randomized, pilot clinical study of elderly subjects receiving antioxidant supplements or a dietar... | Macula; Serum Carotenoids; Zeaxanthin | 2006-02-01 |
| 17 |  | Guanylyl cyclase activating protein. A calcium-sensitive regulator of phototransduction | Baehr, Wolfgang | Guanylyl cyclase activating protein (GCAP1) has been proposed to act as a calcium-dependent regulator of retinal photoreceptor guanylyl cyclase (GC) activity. Using immunocytochemical and biochemical methods, we show here that GCAP1 is present in rod and cone photoreceptor outer segments where photo... | Cloning, Molecular; DNA Primers; Molecular Sequence Data | 1995 |
| 18 |  | Helicase-primase inhibitor pritelivir for HSV-2 infection | Kriesel, John D. | Background Pritelivir, an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. We tested the efficacy and safety of pritelivir in otherwise healthy persons with genital HSV-2 infection. Methods We randomly... | | 2014-01-01 |
| 19 |  | Heterozygous and homozygous mutations in PITX3 in a large Lebanese family with posterior polar cataracts and neurodevelopmental abnormalities | Zhang, Kang | PURPOSE: The PITX3 gene, which codes for a homeobox bicoidlike transcription factor is responsible for dominant cataract and anterior segment mesenchymal dysgenesis in humans. In the current study, a family with autosomal dominant posterior polar cataract (PPC) and a PITX3 mutation that cosegregates... | Chromosomes, Human, Pair 10; Homozygote; Lod Score | 2006 |
| 20 |  | Intraoperative crystallization on the intraocular lens surface | Olson, Randall J.; Crandall, Alan S.; Caldwell, Karin D.; Jensen, Michael K. | PURPOSE: To report a physician survey, laboratory studies, and clinical observations of intraoperative crystallization on the surface of the intraocular lens (IOL). METHOD: We sent a survey to all ophthalmologists in the states of Wyoming, Idaho, Montana, Utah, and Colorado asking whether crystalliz... | Cataract Extraction; Intraoperative Complications; Risk Factors | 1998-08 |
| 21 |  | Intraoperative miotics and posterior capsular opacification following phacoemulsification with intraocular lens insertion | Olson, Randall J.; Crandall, Alan S.; Mamalis, Nick | BACKGROUND AND OBJECTIVES: Posterior capsular opacification (PCO) is a frequent complication following phacoemulsification with intraocular lens (IOL) implantation. A series of consecutive patients receiving capsular bag-fixated, silicone IOL implants were assessed for both incidence of PCO and the ... | Intraocular Lens; Nd:YAG Laser Capsulotomy; Miochol; Miostat; Phacoemulsification; Posterior Capsular Opacification | 1997-11 |
| 22 |  | Invasive sinonasal disease due to Scopulariopsis candida: case report and review of scopulariopsosis. | Kriesel, John D.; Gooch, Willis M.; Pavia, Andrew T. | Sinonasal infection with fungi of the order Mucorales--termed mucormycosis or zygomycosis--is sometimes seen in immunosuppressed patients, including those with diabetic ketoacidosis and malignancy. We describe a case of invasive sinonasal infection with Scopulariopsis candida (not among the Mucorale... | Granulocyte Colony-Stimulating Factor; Itraconazole; Maxillary Sinus | 1994 |
| 23 |  | Update on a long-term, prospective study of capsulotomy and retinal detachment rates after cataract surgery | Olson, Randall J. | PURPOSE: To evaluate the retinal detachment risks and neodymium:YAG (Nd:YAG) capsulotomy rates associated with different cataract approaches and intraocular lens (IOL) styles in a long-term,prospective clinical study. SETTING: Clinical practice of 1 ophthalmologist, Fort Collins, Colorado, USA. METH... | Cataract Extraction; Laser Therapy; Retinal Detachment; Risk Factors | 2000-07 |
| 24 |  | Penetrating keratoplasty for keratoconus: a long-term review of results and complications | Olson, Randall J.; Pingree, Michael F.; Lundergan, Maureen K. | PURPOSE: To study the long-term complications of penetrating keratoplasty (PKP) to evaluate current recommendations to patients with keratoconus. SETTING: John Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. METHODS: Retrospective study of all PKP procedures for keratoconus performe... | Visual Acuity; Refraction, Ocular; Keratoconus; Astigmatism | 2000-07 |
| 25 |  | Phenolic components from the leaves of the Ginkgo tree (Ginkgo biloba L) | Baehr, Wolfgang | No summary- Article is in German. | Flavonoids; Chromatography; Phenols; Plant Extracts; Ginkgo Biloba L. | 1968-05 |
