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TitleCreatorDescriptionSubjectDate
1Intracranial hypotension in the setting of concurrent perineural cyst rupture and subarachnoid hemorrhageIntracranial hypotension in the setting of concurrent perineural cyst rupture and subarachnoid hemorrhageCouldwell, William T.Although most patients with intracranial hypotension typically present with headaches, the rest of the clinical spectrum is characteristically non-specific and often quite variable. In a patient with concurrent pathologies that can produce a similar clinical picture, a high index of suspicion must b...2013-01-01
2Intraoperative aneurysmal subarachnoid hemorrhage after rupture of a previously undiagnosed intracranial aneurysm during Chiari decompression: case report and literature reviewIntraoperative aneurysmal subarachnoid hemorrhage after rupture of a previously undiagnosed intracranial aneurysm during Chiari decompression: case report and literature reviewCouldwell, William T.Type 1 Chiari malformation occurs when caudal displacement of cerebellar tonsils below the level of foramen magnum obstructs the normal flow of cerebrospinal fluid (CSF) between the cranial and spinal spaces, a condition that often needs surgical decompression to restore normal CSF circulation. Abru...2014-01-01
3Unruptured posterior communicating artery aneurysm presenting with gustatory seizures and temporal lobe edemaUnruptured posterior communicating artery aneurysm presenting with gustatory seizures and temporal lobe edemaCouldwell, William T.Unruptured cerebral aneurysms presenting with seizures are unusual. We describe a case of a growing middle cerebral artery aneurysm presenting with gustatory seizures with magnetic resonance imaging showing peri-aneurysmal edema. This case is the first to show temporal lobe edema associated with inc...Seizure; Brain edema; PCOM2009-04
4Medpor implant in cranioorbitomaxillary reconstruction: institutional experience and a review of the literatureMedpor implant in cranioorbitomaxillary reconstruction: institutional experience and a review of the literatureCouldwell, William T.Autologous materials remain the gold standard for complex skull base and craniofacial reconstruction, but they carry additional morbidity associated with the second harvest procedure and with prolonged operation time. These autologous materials also resorb in a way that is not predictable, rendering...Medpor; Alloplastic material; Autogenous tissue; Craniofacial reconstruction; Skull base surgery; Methylmethacrylate; Silicone2008
5Choroid plexus cyst development and growth following ventricular shuntingChoroid plexus cyst development and growth following ventricular shuntingCouldwell, William T.Choroid plexus cysts are typically incidental, asymptomatic cysts. They have been reported to hemorrhage and grow, causing symptoms of obstruction. However, growth and multiplication has not been reported following ventriculoperitoneal shunting procedures. A 66-year-old woman initially underwent a ...Choroid plexus cyst; Ventriculoperitoneal shunt2008-01
6Role of CCM1 loss-of-function-induced endothelial-to-mesenchymal transition in the development  of cavernous malformationsRole of CCM1 loss-of-function-induced endothelial-to-mesenchymal transition in the development of cavernous malformationsCouldwell, William T.Cerebral cavernous malformations (CCM) occur in two variants: sporadic and familial. Mutations in three genes-CCM1, CCM2, and CCM3-play a role in both subtypes, with mouse models showing the development of multiple cavernous malformations in animals with loss of function in any of these three genes....2013-01-01
7Giant pituitary tumor combined approachGiant pituitary tumor combined approachCouldwell, William T.Nishioka et al. have provided a review of 29 patients with large pituitary adenomas who underwent surgery through a simultaneous transsphenoidal and transcranial approach at their institution during a 7-year period. Large adenomas with hourglass constriction, complex lobulations, and asymmetric exte...2012-01-01
8Comparison of the cell lines used in meningoma researchComparison of the cell lines used in meningoma researchCouldwell, William T.; Gillespie, David L.; Jensen, Randy L.Background: Immortal cell lines and cell lines derived from operative specimens transplanted into animal models are used in meningioma research. We address two criticisms of the mouse xenograft flank tumor model: Why are tumor induction rates derived from operative specimens low and inconsistent? Ar...CH-157 MN; IOMM-Lee; Meningioma; Xenograft Mouse Model; Flank tumors2008
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