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Creator | Title | Description | Subject | Date |
501 |
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Farmer, Colleen G. | The pulmonary anatomy of alligator mississippiensis and its similarity to the avian respiratory system | Using gross dissections and computed tomography we studied the lungs of juvenile American alligators (Alligator mississippiensis). Our findings indicate that both the external and internal morphology of the lungs is strikingly similar to the embryonic avian respiratory system (lungs + air sacs). We... | | 2012 |
502 |
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Beckerle, Mary C. | Purification and characterization of an α-actinin-binding PDZ-LIM protein that is up-regulated during muscle differentiation | α-Actinin is required for the organization and function of the contractile machinery of muscle. In order to understand more precisely the molecular mechanisms by which α-actinin might contribute to the formation and maintenance of the contractile apparatus within muscle cells, we performed a scree... | LIM domains; Z-disc; Actin; Actinin-associated LIM proteins; PDZ-LIM protein | 1999 |
503 |
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Capecchi, Mario R. | Purification and characterization of mouse hypoxanthine-guanine phosphoribosyltransferase. | Hypoxanthine-guanine phosphoribosyltransferase (HGPR transferase) (EC 2.4.2.8) has been purified approximately 4500-fold to apparent homogeneity from mouse liver. The procedure involves the use of affinity chromatography and was designed to be readily adaptable to small scale isolations. The enzyme ... | Buffers; Centrifugation, Density Gradient; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel | 1975-01-31 |
504 |
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Beckerle, Mary C. | Purification and characterization of zyxin, an 82,000-Dalton component of adherens junctions | We describe here the purification and characterization of a recently identified adherens junction protein that has an apparent molecular mass of 82 kDa on sodium dodecyl sulfate-polyacrylamide gels (Beckerle, M. C. (1986) J. Cell Biol. 103, 1679-1687). The 82-kDa protein was isolated from avian smoo... | Zyxin | 1992 |
505 |
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Olivera, Baldomero M.; Hillyard, David R. | Pyridine nucleotide cycle: studies in Escherichia coli and the human cell line D98/AH2 | Different metabolic steps comprise the pyridine nucleotide cycles in Escherichia coli and in the human cell line HeLa D98/AH2. An analysis of the "P-labeling patterns in vivo reveals that in E. coli, pyrophosphate bond cleavage of intracellular NAD predominates, while in the human cell line, cleava... | Nicotinic acid; Turnover cycle; DNA ligation; Nicotinamide | 1981 |
506 |
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Olivera, Baldomero M. | Pyridine nucleotide metabolism in Escherichia coli. I. Exponential growth | The pyridine nucleotide pool of Escherichia coli is made up almost exclusively of DPN and TPN. In an exponentially growing glucose culture an average cell contains 1,460,000 molecules of DPN (30% reduced) and 440,000 molecules of TPN (57% reduced). If the total volume of the cell were accessible t... | Nicotinic acid | 1971 |
507 |
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Olivera, Baldomero M. | Pyridine nucleotide metabolism in Escherichia coli. II. Niacin starvation | The effect of niacin starvation has been studied in a niacin-requiring auxotroph of Escherichia coli. If a culture is totally deprived of niacin, cells continue to divide until the total pyridine nucleotide content has fallen from 1.9 X 10^6 to 1.2 X 10^5 molecules per cell. During starvation, the r... | Starvation; Nicotinic acid | 1973 |
508 |
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Olivera, Baldomero M. | Pyridine nucleotide metabolism in Escherichia coli. III. Biosynthesis from alternative precursors in vivo | In Escherichia coli, the nicotinamide moiety of pyridine nucleotides may be derived from de novo synthesis of the pyridine ring or through the uptake of either nicotinic acid or nicotinamide. De novo synthesis is the least preferred pathway; it is suppressed if an exogenous source is available. Nic... | Nicotinic acid; Biosynthesis | 1973 |
509 |
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Olivera, Baldomero M. | Pyridine nucleotide metabolism in Escherichia coli. IV. Turnover | There are two pyridine nucleotide turnover pathways in Escherichia coli, the Gholson turnover cycle, with nicotinamide as an intermediate, and a second new pathway which does not involve nicotinamide. In exponentially growing cultures with a generation time of 60 min, the rates of these cycles are ... | Turnover cycle; Adenine | 1973 |
510 |
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Dale, Colin; Babst, Markus | Quorum sensing primes the oxidative stress response in the insect endosymbiont, Sodalis glossinidius | Sodalis glossinidius, a maternally transmitted bacterial endosymbiont of tsetse flies (Glossina spp.), uses an acylated homoserine lactone (AHL)-based quorum sensing system to modulate gene expression in accordance with bacterial cell density. The S. glossinidius quorum sensing system relies on the... | Endosymbionts; Sodalis glossinidius; Quorum sensing; Oxidative stress response | 2008 |
511 |
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Coley, Phyllis D. | Rates of herbivory on different tropical trees | Rates of herbivory on marked young and mature leaves from saplings of 21 canopy tree species were measured in the wet and dry seasons. Species were classified into two life history groups: persistent species which are found throughout the shaded understory, and pioneer species which only become e... | Herbivory; Grazing damage; Tropical trees; Pioneer species; Trees -- Tropics | 1982 |
512 |
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Adler, Frederick R. | Recent rapid increases in the right whale (Eubalaena australis) population off southern Brazil | Right whales (Eubalaena australis) that gather on a wintering ground off southern Brazil have been aerial surveyed and photographically identified since 1987. As of 2003 the Brazilian Right Whale Catalogue has 315 different individual whales of which 31 were resighted in other years (23 females, 3 y... | | 2005 |
513 |
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Frederick, Jeanne M.; Baehr, Wolfgang | Receptor for advanced glycation end products and age-related macular degeneration. | Advanced glycation end products (AGE) exacerbate disease progression through two general mechanisms: modifying molecules and forming nondegradable aggregates, thus impairing normal cellular/tissue functions, and altering cellular function directly through receptor-mediated activation. In the present... | Optic Atrophies, Hereditary; Apoptosis; Pigment Epithelium of Eye | 2004 |
514 |
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Clayton, Dale H. | Reciprocal natural selection on host-parasite phenotypes | Coevolution is evolution in one species in response to selection imposed by a second species, followed by evolution in the second species in response to reciprocal selection imposed by the first species. Although reciprocal selection is a prerequisite of coevolution, it has seldom been documented in... | Host-parasite phenotypes; Ectoparasites; Virulence; Fitness | 1999 |
515 |
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Crespo, Jose Guillermo | Recruitment of motor units in flight muscles accounts for pheromone-mediated modulation of pre-flight heating rates of males moths | | Insecta; Physiology; Pheromone; Thermobiology; Muscle; Flight; Behavior; Helicoverpa zea | 2013 |
516 |
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Ehleringer, James R.; Negus, Norman C. | Red Butte Canyon Research Natural Area: history, flora, geology, climate, and ecology | Red Butte Canyon is a protected, near pristine canyon entering Salt Lake Valley, Utah. It contains a well-developed riparian zone and a perennial stream; hillside vegetation ranges from grasslands on the lower limits to Douglas-fir and aspen stands at the upper elevations. In this paper we describe ... | Intermountain West; Grassland; Oak-maple; Plant adaptation; Red Butte Canyon Research Natural Area; Human impact | 1992 |
517 |
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Coley, Phyllis D. | Red coloration of tropical young leaves: a possible antifungal defense? | Many woody species in humid tropical forests synchronously flush entire canopies of young red leaves. Numerous unsuccessful attempts have been made to explain the adaptive value of this visually striking phenomenon. In the humid tropics, fungal attack is a potentially important source of mortality f... | Herbivory; Anthocyanin; Antifungal defense; Atta columbica; Panama; Leaf-cutting ants; Tropics; Young leaves | 1989 |
518 |
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Capecchi, Mario R. | Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. | Mutations were targeted to the Hprt locus of mouse embryo-derived stem cells by using 22 different sequence replacement and sequence insertion vectors. The targeting frequency was examined at two sites within the Hprt locus as a function of the extent of homology between the targeting vector and the... | Cell Line; DNA Transposable Elements; Embryo; Exons; Mice | 1992-08-12 |
519 |
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Capecchi, Mario R. | Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5. | Gene targeting in mouse embryo-derived stem cells has been used to disrupt the homeobox gene hox-1.5. Mice heterozygous at the hox-1.5 locus appear normal, whereas hox-1.5-/hox-1.5- mice die at or shortly after birth. These homozygotes are athymic, aparathyroid, have reduced thyroid and submaxillary... | Abnormalities, Multiple; Animals, Newborn; Arteries; Bone and Bones; Cartilage; Esophagus; Gene Expression; Heart Defects, Congenital; Organ Specificity; Parathyroid Glands; Pharynx; Thymus Gland; Thyroid Gland; Trachea | 1991-04-11 |
520 |
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Sperry, John S. | Relationship between xylem conduit diameter and cavitation caused by freezing | The centrifuge method for measuring the resistance of xylem to cavitation by water stress was modified to also account for any additional cavitation that might occur from a freeze-thaw cycle. A strong correlation was found between cavitation by freezing and mean conduit diameter. | Embolism; freezing stress; hydraulic conductivity | 1999 |
521 |
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Potts, Wayne K. | Relationship of virulence factor expression to evolved virulence in mouse-passaged Cryptococcus neoformans lines | Serial passage of Cryptococcus neoformans in mice increases virulence relative to the nonpassaged line. Postpassaged lines showed no difference in the expression of most known virulence factors, with the exception that the more virulent lines had smaller capsules in vitro. These data imply that othe... | Capsule; Death; Passage | 2005 |
522 |
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Capecchi, Mario R. | Removing the vertebrate-specific TBP N terminus disrupts placental beta2m-dependent interactions with the maternal immune system | Mammalian TBP consists of a 180 amino acid core that is common to all eukaryotes, fused to a vertebrate-specific N-terminal domain. We generated mice having a modified tbp allele, tbp(DeltaN), that produces a version of TBP lacking 111 of the 135 vertebrate-specific amino acids. Most tbp(DeltaN/Delt... | Alleles; Animals, Genetically Modified; Binding Sites; Embryonic and Fetal Development; Evolution, Molecular; Female; Fetus; Immune Tolerance; Male; Mice; Mutation; ATA-Box Binding Protein | 2002-07-12 |
523 |
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Adler, Frederick R. | Reply: | We appreciate the comments of Drs. Craig and Simpson and Drs. Mullins and Schwartz, and the challenge they raise to make MALD more believable, comprehensible, and usable. Acetaminophen (APAP) toxicity is indeed a complex process involving multiple steps. Although the underlying mathematics is more i... | | 2012-01-01 |
524 |
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Farmer, Colleen G. | Reproduction: the adaptive significance of endothermy | A central theme raised by Angilletta and Sears is that the energetic cost of endothermy is too enormous to be offset by the benefits that thermogenesis could provide for reproduction. Angilletta and Sears suggest that parents would have been better off producing additional offspring with the energy ... | Parental care; Incubation; Metabolism | 2003 |
525 |
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Varner, Johanna M.; Dearing, Maria-Denise | Research data to accompany Varner and Dearing 2014 "Relevant Microclimates and Habitat Suitability" | Data package to accompany "Relevant Microclimates and Habitat Suitability". Package contains a ReadMe file and the following Excel spreadsheets: Elevation Comparison, Moss Transplant Data, Tempdata by site, Variogram-Ambient, Variogram_Ambient Shortrange, Variogram-Surf, Variogram-Talus. | Research data; Relevant microclimates; Habitat suitability | 2014 |