UScholar Works
 
Filters: Department: "Biology" Collection: ir_uspace
426 - 450 of 649
Number of results to display per page
CreatorTitleDescriptionSubjectDate
426 Olivera, Baldomero M.; Bulaj, GrzegorzNovel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptorsWe report the discovery and characterization of three conantokin peptides from the venom of Conus parius. Each peptide (conantokin-Pr1, -Pr2, and -Pr3) contains 19 amino acids with three γ-carboxyglutamate (Gla) residues, a post-translationally modified amino acid characteristic of conantokins. The...Conotoxins; Conantokins; Conus parius; Antagonists; n-methyl-D-aspartate receptors2007
427 Olivera, Baldomero M.Novel Conus peptide ligand for K+ channelsVoltage-gated ion channels determine the membrane excitability of cells. Although many Conus peptides that interact with voltage-gated Na+ and Ca2+ channels have been characterized, relatively few have been identified that interact with K+ channels. We describe a novel Conus peptide that intera...Conus peptides; Conotoxins2003
428 Coley, Phyllis D.; Kursar, Thomas A.Novel DNA-based microfluorimetric method to evaluate antimalarial drug activityThis paper describes the development of a novel microfluorimetric assay to measure the inhibition of Plasmodium falciparum based on the detection of parasitic DNA by intercalation with PicoGreen®. The method was used to determine parasite inhibition profiles and 50% inhibitory concentration values ...Microfluorimetric assay; Plasmodium falciparum; Chloroquine; Drug discovery2004
429 Olivera, Baldomero M.; McIntosh, J. MichaelNovel post-translational modification involving bromination of tryptophan: identification of the residue, L-6-bromotryptophan, in peptides from Conus imperialis and Conus radiatus venomWe report a novel post-translational modification involving halogenation of tryptophan in peptides recovered from the venom of carnivorous marine cone snails (Conus). The residue, L-6-bromotryptophan, was identified in the sequence of a heptapeptide, isolated from Conus imperialis, a worm-hunting...Conotoxins; Conus imperialis; Conus radiatus; L-6-bromotryptophan1997
430 Olivera, Baldomero M.Novel venom peptides from the cone snail Conus pulicarius discovered through next-generation sequencing of its venom duct transcriptomeThe venom peptides (i.e., conotoxins or conopeptides) that species in the genus Conus collectively produce are remarkably diverse, estimated to be around 50,000 to 140,000, but the pace of discovery and characterization of these peptides have been rather slow. To date, only a minor fraction have be...2012
431 Olivera, Baldomero M.; McIntosh, J. MichaelNuclear magnetic resonance solution conformation of α-conotoxin AuIB, an α3ß4 subtype-selective neuronal nicotinic acetylcholine receptor antagonistThe neuronal nicotinic acetylcholine receptors constitute a highly diverse group, with subtypes consisting of pentameric combinations of α and ß subunits. α-Conotoxins are a homologous series of small peptides that antagonize these receptors. We present the three-dimensional solution structure ...Conotoxins; a-conotoxin AuIB2000
432 Beckerle, Mary C.Nuclear-cytoplasmic shuttling of the focal contact protein, zyxin: a potential mechanism for communication between sites of cell adhesion and the nucleusIntegrin-dependent cell adhesion to specific extracellular matrix molecules has been demonstrated to trigger dramatic changes in gene expression that can affect cell fate. However, little is understood about the molecular mechanism by which events at sites of cell-substratum adhesion are communicate...Zyxin; Cytosol; Nuclear export signal1997
433 Seger, JonNumerical method for estimating coefficients of relationship in a langur troopThe average coefficient of relationship ( r ij) among the members of a social group is expected to influence the evolution of any trait that affects the average fitness of group members other than the bearer of the trait. It is usually impossible to write a general expression for r ij , because it...Mating; Reproduction; Trait1977
434 Sperry, John S.Observations of reaction fibers in leaves of dicotyledonsHALLE, OLDEMAN, AND TOMLINSON (1978) have discussed the transference of function between compound leaves and plagiotropic branches in the context of tree architecture. In trees conforming to Cook's model (see Halle, Oldeman, & Tomlinson, 1978), plagiotropic branches resemble compound leaves in their...Reaction fibers; Compound leaves1982
435 Sperry, John S.Observations on the structure and function of hydathodes in Blechnum lehmaniiThe fronds of many ferns in the Polypodiaceae (Ogura, 1972) and Cyatheaceae (Weiler, cited in Lippmann, 1925) possess swollen vein endings associated with specialized adaxial epidermal cells. Their structure is similar in all ferns (Gardiner, 1883; Potonie, 1892; Poirault, 1893; Goebel, 1930; Gutten...Hydathodes; Blechnum lehmannii; Root pressure; Secretion1983
436 Crespo, Jose GuillermoOlfactory modulation of pre-flight shivering behavior in male mothsIn nocturnal moths olfaction is the predominant sensory modality shaping many of the adult animal?s activities, including reproduction. A two-component pheromone blend is sufficient to elicit the typical zigzag upwind flight behavior in Helicoverpa zea males. However, before flight can be initiated,...thermoregulation, warm-up, flight, sex pheromone, Noctuidae, insect Department: Biology2011-01-02
437 Olivera, Baldomero M.On a potential global role for vitamin K-dependent γ-carboxylation in animal systemsThe vitamin K-dependent γ-carboxylation of glutamate to γ-carboxyglutamate was originally well characterized in the mammalian blood clotting cascade. γ-Carboxyglutamate has also been found in a number of other mammalian proteins and in neuropeptides from the venoms of marine snails belonging to...Carboxylation; Glutamate; Carboxyglutamate; Carboxylase mRNA; Conantokin G2001
438 Olivera, Baldomero M.On the mechanism of the polynucleotide joining reactionPolynucleotide-joining enzymes (ligases) have been identified in uninfected and phage-infected Escherichia coli (Gellert, 1967; Olivera and Lehman, 1967a; Zimmerman et al., 1967; Gefter et al., 1967; Weiss and Richardson, 1967a; Cozzarelli et al., 1967). Both types of enzyme catalyze the synthesis o...Enzyme-AMP; Enzyme-Adenylate; DNA-Adenylate; Poly dt-Adenylate; Pyrophosphate bond1968
439 Coley, Phyllis D.On tropical forests and their pestsBiologists have long been intrigued by the diversity of tropical forests, where 1 hectare may hold more than 650 tree species-more than in all of Canada and the continental United States. Eco- logical theory suggests that if species are too similar in their resource use, one will out- compete the ot...2014-01-01
440 Coley, Phyllis D.On turning green into goldAnthropogenic effects on the climate and biodiversity of our planet are among the most troubling and perhaps irreversible threats facing scientists, policymakers, and citizens. Yet many scientists are reluctant or unsure of how to apply their expertise in basic science to these pressing real-world p...Bioprospecting; Drug discovery; Active compounds; Panama2008
441 Goller, FranzOntogeny of song lateralization in juvenile northern cardinalsIn adult northern cardinals (Cardinatte cardinalis), the left and right sides of the syrinx cover different vocal registers such (hat fundamental frequencies below about 3.5 or 4 kHz are produced only by the left syrinx and higher frequencies are produced primarily by the light syrinx.Motor control; FM sweep; Subsong1998
442 Jorgensen, ErikOpen syntaxin docks synaptic vesiclesSynaptic vesicles dock to the plasma membrane at synapses to facilitate rapid exocytosis. Docking was originally proposed to require the soluble N-ethylmaleimide-sensitive fusion attachment protein receptor (SNARE) proteins; however, perturbation studies suggested that docking was independent of the...2007
443 Beckerle, Mary C.Opposing roles of zyxin/LPP ACTA repeats and the LIM domain region in cell-cell adhesionCadherins mediate cell-cell adhesion by linking cell junctions to actin networks. Although several actin regulatory systems have been implicated in cell-cell adhesion, it remains unclear how such systems drive cadherin-actin network formation and how they are regulated to coincide with initiation o...Zyxin; Actin; Cadherin; LIM domains; VASP2006
444 Adler, Frederick R.Optimal tempo and defence for consumers of multiple resourcesEcological models of behaviour are typically based on the assumption that decisions can be evaluated with a single resource currency. Here we present models that predict the tactics of consumers collecting two nutritionally distinct resources: fuel that is used for activity and food used for growth ...Defence; Optimal foraging; Provisioning2003
445 Adler, Frederick R.Optimization, conflict, and nonoverlapping foraging ranges in antsAn organism's foraging range depends on the behavior of neighbors, the dynamics of resources, and the availability of information. We use a well-studied population of the red harvester ant Pogonomyrmex barbatus to develop and independently parameterize models that include these three factors. The mo...Colony; Space; Model2003
446 Ehleringer, James R.Orientation and slope preference in barrel cactus (Ferocactus acanthodes) at its northern distribution limitMicrosite distribution and diurnal tissue temperature fluctuations were measured in Ferocactus acanthodes (barrel cactus) at its northern distribution limit in the Beaver Dam Mountains of southwestern Utah. At this location, barrel cacti were limited to south-facing slopes. Orientation (azimuth an...Ferocactus acanthodes; Barrel cactus; Slope preference1984
447 Gesteland, Raymond F.; Atkins, John F.Origin and destiny of adenovirus proteinsLytic infection of human cells by adenovirus proceeds by a temporal expression of genes. Classically two phases have been defined: an early phase, which includes events occurring before the onset of DNA synthesis (8 hours), and a late phase, including events whose existence depends on the onset of...Protein Biosynthesis; DNA, Viral; Adenoviridae; RNA, Viral; Time Factors1975
448 Ehleringer, James R.Oxygen isotope ratios of waters and respired CO2 in Amazonian forest and pasture ecosystemsThe oxygen isotope ratio (d18O, SMOW) of atmospheric CO2 is a powerful indicator of large-scale CO2 exchange on land. Oxygen isotopic exchange between CO2 and water in leaves and soils controls the d18O of atmospheric CO2. Currently there is little empirical information on the spatial and temporal ...Amazonia; Carbon dioxide (CO2); Oxygen isotope ratio; Photosynthesis; Respiration; Stable isotope ratio; Tropical forests2005
449 Gesteland, Raymond F.; Atkins, John F.; Baranov, Pavel V.P-site tRNA is a crucial initiator of ribosomal frameshiftingThe expression of some genes requires a high proportion of ribosomes to shift at a specific site into one of the two alternative frames. This utilized frameshifting provides a unique tool for studying reading frame control. Peptidyl-tRNA slippage has been invoked to explain many cases of programmed ...Translation; Recoding; Kinetic Model; Frameshifting; Ribosome2004
450 Olivera, Baldomero M.P-superfamily conopeptidesThe present invention is directed to P-superfamily conopeptides, to DNA encoding precursors of the P-superfamily conopeptides and to the precursor peptides.2006
426 - 450 of 649