|
|
Creator | Title | Description | Subject | Date |
| 1 |
 | Goller, Franz | Vorkommen und Brut des Bienenfressers (Merops apiaster) in Osttirol (Österreich) (Aves: Meropidae) | Synopsis: The first record of Bee-eater for the Eastern Tyrol is imparted by KL1MSCH (1950), three further observations are mentioned. In 1983 a breeding place was discovered near Lavant in about 650 m NN. Feeding adults were watched on the 11th and 12th of August. The breeding place is briefly desc... | Merops apiaster; Meropidae; Tyrol | 1984 |
| 2 |
 | Olivera, Baldomero M.; McIntosh, J. Michael; Hillyard, David R. | A-superfamily of conotoxins: structural and functional divergence | The generation of functional novelty in proteins encoded by a gene superfamily is seldom well documented. In this report, we define the A-conotoxin superfamily, which is widely expressed in venoms of the predatory cone snails (Conus), and show how gene products that diverge considerably in stru... | Conotoxins; A-superfamily conotoxin | 2004-02-03 |
| 3 |
 | Shapiro, Michael D. | Adaptive evolution of pelvic reduction in sticklebacks by recurrent deletion of a Pitx1 enhancer | The molecular mechanisms underlying major phenotypic changes that have evolved repeatedly in nature are generally unknown. Pelvic loss in different natural populations of threespine stickleback fish has occurred by regulatory mutations deleting a tissue-specific enhancer of the Pituitary homeobox t... | Adaptive evolution; Pelvic reduction; Pituitary homeobox transcription factor 1; Pitx1; Gasterosteus aculeatus | 2010-01-14 |
| 4 |
 | Capecchi, Mario R. | Fundamental cellular processes do not require vertebrate-specific sequences within the TATA-binding protein. | The 180-amino acid core of the TATA-binding protein (TBPcore) is conserved from Archae bacteria to man. Vertebrate TBPs contain, in addition, a large and highly conserved N-terminal region that is not found in other phyla. We have generated a line of mice in which the tbp allele is replaced with a v... | Mice, Knockout; Cells, Cultured; Fibroblasts; Embryo | 2003-02-21 |
| 5 |
 | Capecchi, Mario R. | Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures. | Hox genes encode transcription factors that are used to regionalize the mammalian embryo. Analysis of mice carrying targeted mutations in individual and multiple Hox genes is beginning to reveal a complex network of interactions among these closely related genes which is responsible for directing th... | Abnormalities, Multiple; Gene Targeting; Glossopharyngeal Nerve; Mice, Knockout; Morphogenesis | 1997-12-15 |
| 6 |
 | Linton, Matthew J. | Magnitude and mechanisms of disequilibrium between predawn plant and soil water potentials | Predawn plant water potential (Uw, measured with leaf psychrometers) and surrogate measurements made with the pressure chamber (termed Upc here) are used to infer comparative ecological performance, based on the expectation that these plant potentials reflect the wettest soil Uw accessed by roots. T... | Roots; Transpiration; Solutes | 2003 |
| 7 |
 | Adler, Frederick R. | Alternating host cell tropism shapes the persistence, evolution and coexistence of Epstein-Barr virus infections in human | Epstein-Barr virus (EBV) infects and can persist in a majority of people worldwide. Within an infected host, EBV targets two major cell types, B cells and epithelial cells, and viruses emerging from one cell type preferentially infect the other. We use mathematical models to understand why EBV infec... | | 2011 |
| 8 |
 | Olivera, Baldomero M.; Gray, William Robert | Contryphan is a D-tryptophan-containing Conus peptide | In this report, we document for the first time the occurrence of D-tryptophan in a normally translated polypeptide, contryphan. The peptide, isolated from the venom of the fish-hunting marine snail Conus radiatus, produces the "stiff-tail" syndrome in mice. | Conotoxins; Contryphan; D-tryptophan; Conus peptides; Conus radiatus; Stiff-tail syndrome | 1996 |
| 9 |
 | Goller, Franz | Respiratory motor correlates of song plasticity in young adult zebra finches | Young adult zebra finches (Taeniopygia guttata, 90150 phd) sing a stereotyped song, but can show rapid changes in song structure if sensory feedback is disrupted. The vocal motor correlates accompanying induced song plasticity have not yet been examined. To investigate motor changes underlying song ... | Pattern; Muting; Sound | 2002 |
| 10 |
 | Capecchi, Mario R. | Hox genes and mammalian development | We have examined the interactions of Hox genes in forming a cervical vertebrae, hindbrain, and limbs. In each case, it is apparent that individual Hox genes are performing individual functions but that more profound roles are apparent when they act in combination with others Hox genes. The observed ... | Drosophila; Gene Expression Regulation, Developmental; Homozygote | 1997 |
| 11 |
 | Olivera, Baldomero M.; Hillyard, David R.; Gray, William Robert | ĸ-Conotoxin PVIIA is a peptide inhibiting the Shaker K+ channel | ĸ-Conotoxin PVIIA (k-PVIIA), a 27-amino acid toxin from Conus purpurascens venom that inhibits the Shaker potassium channel, was chemically synthesized in a biologically active form. The disulfide connectivity of the peptide was determined. ĸ-Conotoxin PVIIA has the following structure. | Conotoxins; k-Conotoxin PVIIA; Conus purpurascens | 1998 |
| 12 |
 | Frederick, Jeanne M.; Baehr, Wolfgang | Receptor for advanced glycation end products and age-related macular degeneration. | Advanced glycation end products (AGE) exacerbate disease progression through two general mechanisms: modifying molecules and forming nondegradable aggregates, thus impairing normal cellular/tissue functions, and altering cellular function directly through receptor-mediated activation. In the present... | Optic Atrophies, Hereditary; Apoptosis; Pigment Epithelium of Eye | 2004 |
| 13 |
 | Adler, Frederick R. | Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics | Relatively little is known about the viral factors contributing to the lethality of the 1918 pandemic, although its unparalleled virulence was likely due in part to the newly discovered PB1-F2 protein. This protein, while unnecessary for replication, increases apoptosis in monocytes, alters viral po... | | 2011 |
| 14 |
 | Sperry, John S. | Relationship between xylem conduit diameter and cavitation caused by freezing | The centrifuge method for measuring the resistance of xylem to cavitation by water stress was modified to also account for any additional cavitation that might occur from a freeze-thaw cycle. A strong correlation was found between cavitation by freezing and mean conduit diameter. | Embolism; freezing stress; hydraulic conductivity | 1999 |
| 15 |
 | Bastiani, Michael | Pathfinding by growth cones in the central nervous system of the grasshopper embryo | In the grasshopper embryo the morphological development of individually identified neurons can be traced prior to the onset of axonogenesis on through maturity (eg., Goodman and Spitzer, 1979). The behavior of individual growth cones can be characterized in their natural environment as they extend t... | | 1982-06-03 |
| 16 |
 | Capecchi, Mario R. | Lack of angiotensin II-facilitated erythropoiesis causes anemia in angiotensin-converting enzyme-deficient mice | While nephrologists often observe reduced hematocrit associated with inhibitors of angiotensin-converting enzyme (ACE), the basis for this effect is not well understood. We now report that two strains of ACE knockout mice have a normocytic anemia associated with elevated plasma erythropoietin level... | | 2000 |
| 17 |
 | Cieri, Robert | New insight into the evolution of the vertebrate respiratory system and the discovery of unidirectional airflow in iguana lungs | The generally accepted framework for the evolution of a key feature of the avian respiratory system, unidirectional airflow, is that it is an adaptation for efficiency of gas exchange and expanded aerobic capacities, and therefore it has historically been viewed as important to the ability of birds ... | | 2014-11-17 |
| 18 |
 | Bohs, Lynn A. | Phylogeny of the carolinense clade of solanum (Solanaceae) inferred from nuclear and plastid DNA sequences | The large and economically important genus Solanum contains ca. 1,400 species distributed worldwide. One of the 12-14 major clades identified in the genus is the Leptostemonum clade, or the "spiny solanums." Previous molecular phylogenetic studies have identified 14 major clades in the spiny solanum... | | 2014-01-01 |
| 19 |
 | Adler, Frederick R. | Reply: | We appreciate the comments of Drs. Craig and Simpson and Drs. Mullins and Schwartz, and the challenge they raise to make MALD more believable, comprehensible, and usable. Acetaminophen (APAP) toxicity is indeed a complex process involving multiple steps. Although the underlying mathematics is more i... | | 2012-01-01 |
| 20 |
 | Capecchi, Mario R. | Modeling alveolar soft part sarcomagenesis in the mouse: a role for lactate in the tumor microenvironment | Alveolar soft part sarcoma (ASPS), a deadly soft tissue malignancy with a predilection for adolescents and young adults, associates consistently with t(X;17) translocations that generate the fusion gene ASPSCR1-TFE3. We proved the oncogenic capacity of this fusion gene by driving sarcomagenesis in m... | | 2014-01-01 |
| 21 |
 | Olivera, Baldomero M. | Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails | Background: Conotoxins can be utilized to investigate enzyme-assisted folding of disulfide-rich peptides. Results: Various ER-resident cone snail enzymes act in concert to accelerate the oxidative folding of conotoxins and modulate their conformation by reconfiguring disulfide connectivities. Conclu... | | 2012-01-01 |
| 22 |
 | Parkinson, John Stansfield | Mutational analysis of the P1 phosphorylation domain in E. coli CheA, the signaling kinase for chemotaxis | The histidine autokinase CheA functions as the central processing unit in the Escherichia coli chemotaxis signaling machinery. CheA receives autophosphorylation control inputs from chemoreceptors and in turn regulates the flux of signaling phosphates to the CheY and CheB response regulator proteins... | | 2014-01-01 |
| 23 |
 | Jorgensen, Erik | Nano-fEM: Protein localization using photo-activated localization microscopy and electron microscopy | Mapping the distribution of proteins is essential for understanding the function of proteins in a cell. Fluorescence microscopy is extensively used for protein localization, but subcellular context is often absent in fluorescence images. Immuno-electron microscopy, on the other hand, can localize pr... | | 2012-01-01 |
| 24 |
 | Capecchi, Mario R. | Sepp1UF forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1 | Mouse selenoprotein P (Sepp1) consists of an N-terminal domain (residues 1-239) that contains 1 selenocysteine (U) as residue 40 in a proposed redox-active motif (-UYLC-) and a Cterminal domain (residues 240-361) that contains 9 selenocysteines. Sepp1 transports selenium from the liver to other tiss... | | 2014-01-01 |
| 25 |
 | Farmer, Colleen G. | Unidirectional pulmonary airflow patterns in the savannah monitor lizard | The unidirectional airflow patterns in the lungs of birds have long been considered a unique and specialized trait associated with the oxygen demands of flying, their endothermic metabolism1 and unusual pulmonary architecture2,3. However, the discovery of similar flow patterns in the lungs of crocod... | | 2014-02-20 |
