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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
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Gardner, Shalyce | Functional test for possible genetic modififers of piga defficiency | PIGA deficiency is a rare X-linked recessive disorder that lacks effective treatment options. A protein encoded by the PIGA gene catalyzed the first step in biosynthesis of Glycosylphatidylinositol (GPI) anchors. Partial loss of function mutations in PIGA can prevent a cell from being able to synthe... | 2023 | |
| 2 |
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Chong, Alisha | Effects of increasing sleep duration on C-Reactive protein, insulin sensitivity, and blood pressure in adults with habitual short sleep | Short sleep, cardiovascular disease, and type 2 diabetes are all highly prevalent health issues in modern society. Previous findings demonstrate that obtaining short sleep is linked to an increased risk of cardiometabolic diseases such as type 2 diabetes and heart disease. However, the mechanisms un... | 2023 | |
| 3 |
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Enriquez, Trisha Pauline Diaz | Substrate use within the drosophila melanogaster species subgroup | Effective sensory perception is a vital aspect of survival for living organisms such as Drosophila. More specifically, olfaction, or the sense of smell, is essential because the detection of odors allows it to find potential food, danger, or specifically, where to lay eggs. This review will examine ... | 2021 | |
| 4 |
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Brown, Audrey | Analyzing response patterns of olfactory bulb glomeruli at low odorant concentration regimes | Sensory input to the olfactory system begins with the binding of an odorant molecule to an olfactory receptor (OR) contained on the surface of an olfactory sensory neuron (OSN). Olfactory bulb (OB) glomeruli receive information from OSNs containing the same OR type and are thought to help process se... | 2021 | |
| 5 |
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Amaechi, Ayana | Understanding sex differences in early predictors of pathological aggression with a mouse model | Antisocial behavior (ASB) is characterized by aggression, violence, drug use, thrillseeking behavior, and delinquent behavior. While childhood and adolescent maltreatment contribute to the ontogeny of this condition, converging evidence suggests that genetic factors play an equally important role. T... | MAOA; pathological aggression; sex differences; stress; early development; animal models | 2021 |
| 6 |
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Som, Sarita | Virus-like weapons used for competition in wild plant populations | Plant diseases caused by bacterial pathogens pose significant economic challenges globally, necessitating the exploration of alternative methods for controlling bacterial infections in plants. Tailocins, virus-like weapons produced by bacteria, have emerged as potent antibacterial agents and hold po... | 2023 | |
| 7 |
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Kober, Derek | Anthropogenic Climate Change and Pollen Trends: Analyzing genera-specific impacts and correlations with temperature and precipitation across the United States (1990-2018) | Studies have shown that human-driven climate change is associated with both higher airborne pollen concentrations and extended allergy seasons. Research particularly indicates that the concentration of pollen is positively correlated to increasing temperatures. This study aims to analyze the pollen ... | 2023 | |
| 8 |
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Rowe, Ana Bruns | The suppression of signal-switching defects in the Escherichia coli serine chemoreceptor | The model bacterium Escherichia coli contains a chemotaxis system that allows the cell to change its swimming behavior in response to its environment. As the cell swims, transmembrane chemoreceptors detect concentration changes in attractant and repellent compounds and transmit signals across the in... | 2023 | |
| 9 |
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Luong, Katie | An examination of the relationship between positive covid-19 infection and vaccine hesitancy within the Utah recover study population | Vaccine hesitancy is defined by the World Health Organization as a "delay in acceptance or refusal of vaccines despite availability of vaccination services," and is affected by a wide range of factors. Some of these factors identified in the literature include perceived safety and importance of vacc... | 2023 | |
| 10 |
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Larson, Brooke | Chacterization of signaling to the degradative pathways of the cell | Protein degradation in cells is a complex network of pathways that are distinct from each other but highly interconnected. Understanding how proteins are degraded in cells is important for understanding and developing treatments for diseases such as lysosomal storage diseases and neurodegenerative d... | 2023 | |
| 11 |
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Identification of potential causes for increased central line associated bloostream infection rates in the University of Utah NICU | The University of Utah Newborn Intensive Care Unit (UUNICU) has seen a recent increase in rate of Central Line Associated Bloodstream Infection (CLABSI) after an extended period of 965 days with no CLABSI's. Unfortunately, in the last three years, infection rate has been on average 2.6 CLABSI per ye... | 2023 | ||
| 12 |
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Barnick, Kelsey | Understanding the role of interstate highway 80 on mammalian community composition of the Wasatch Mountain range using camera traps | 2020 | ||
| 13 |
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Peterson, Mikal | Somatic chromosome pairing in interspecific drosophila hybrid and hybried rescue crosses | Homologous chromosomes of somatic tissue pair together in Drosophila. One current model proposes that somatic pairing starts in an undirected manner; when sites on the chromosome, called "buttons", come into contact and pair. Then, after this initial pairing, the rest of the chromosome then synapses... | 2022 | |
| 14 |
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Mallender, Zachary | Assay of the dreem device on sleep metrics and an exploration of sleep staging in chronic short sleepers during time in bed extension | Despite clear and plentiful research that sleeping less than seven hours per night has a wide array of health consequences, a large portion of American adults report sleeping less than seven hours per night and thus receive chronic insufficient sleep. Many studies exploring the consequences of insuf... | 2022 | |
| 15 |
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Olivia Hanson | Spinal cord injury-induced neuropathic pain & the gut microbiome: a review | Most spinal cord injuries (SCI) result in spinal cord injury-induced neuropathic pain (SCINP). SCI-NP is a major healthcare concern given the extensive burden it places on both patients and the healthcare system. This, coupled with the lack of effective and available treatments for those suffering f... | 2022 | |
| 16 |
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Andersen, Kara | Cervical dorsal root ganglion imaging for studying neuronal nocicieptive ciruit changes in migranine models | Migraine neuroscience is a field in its infancy, with migraine being a remarkably common yet poorly understood sensory circuit disorder. It is characterized by attacks of unilateral, throbbing craniofacial pain, with sensitivity to movement, visual, auditory, and other afferent inputs. Migraines can... | 2022 | |
| 17 |
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Tazehabadi, Tara | Bioinformatics to detect functional interactions important for the DNA repair enzyme mutyh | DNA is the blueprint of all biological life as it provides the means necessary for sharing of genetic information. DNA is formed and stabilized by interactions between four unique bases, Adenine (A), Cytosine (C), Guanine (G), and Thymine (T) which come together in predetermined patterns to create a... | 2022 | |
| 18 |
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Thomas, Nathaniel | The HIV-protective bystander effect in macrophages is viral glycoprotein dependent and likely conferred via upregulation of ISG IFITM3 | During an immune response against a specific antigen, often during viral infections, T cells not specific to the antigen can be activated, a phenomenon known as bystander response. The "bystander response" has been studied extensively in T cells, but when examined for macrophages through the lens of... | 2022 | |
| 19 |
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Watson, Andre | Patterns of parasitism in a common Utah Rodent | Male-biased parasitism, where males are more commonly infected with and have higher parasite loads, is common across vertebrate taxa. Several factors could be driving this pattern. The immunocompetence handicap hypothesis suggests that higher testosterone levels in males suppress immune function whi... | 2022 | |
| 20 |
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Rohaj, Aarushi | Apoptosis efficiency of the transfected elephant and human P35 vectors in P53 varying leiomyosarcoma cells | Comparative Oncology is an approach that integrates and connects commonly occurring cancers seen in animals, into studies focused on cancer biology, prevention, and treatment in humans. Studies show that natural mechanisms can suppress cancer 1,000 times more adequately in certain animals than in hu... | 2021 | |
| 21 |
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Lee, Hani | Post-traumatic headache: an opportunity to develop new preclinical models for better understanding of pathology and treatment | Post-traumatic headache (PTH) is identified as one of the most frequent symptoms following traumatic brain injury (TBI) (Faux & Sheedy, 2008). Despite the high prevalence, there are currently no treatments which specifically target PTH. Instead of etiology-specific treatments, individuals suffering ... | 2022 | |
| 22 |
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Lan, Yung-Chi | HYPO-osmolarity and glucose starvation localizes slm1 to mitochondria- A novel stress response pathway | Synthetic Lethal with Mss4 1 (Slm1) is a key protein found in the crossroad of the Membrane Compartment of Can1 (MCC) and the Membrane Compartment of TORC2 (MCT). The two compartments on the plasma membrane of budding yeast (Saccharomyces cerevisiae) are responsible for APC transporter regulation an... | 2022 | |
| 23 |
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Kasera, Shalini | Effect of IUGR and supplemental DHA on molecular mediators of hepatic lipid accumulation in the rat | Intrauterine growth restriction (IUGR) refers to failure of the fetus to achieve its genetic growth potential in utero and is commonly caused by uteroplacental insufficiency secondary to maternal hypertensive disorders. A hallmark of IUGR is a decrease in circulating docosahexaenoic acid (DHA), an �... | 2022 | |
| 24 |
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Hahm, Suhyun | Stressors of varying properties induce differences in the modulation of behavior and biology | Stress induces enduring behavioral and biological consequences. Despite its pervasiveness, the biological and neural processes underlying its effects remain largely unknown. The existing literature generally examines the repercussions of stress from the aspect of a single stressor; however, stressor... | 2022 | |
| 25 |
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Jensen, Madeline | Changes in microbial diversity in storm-water green infrastructure | Increased urbanization has led to excess nutrients in urban ecosystems. Stormwater Green Infrastructure (SGI) is a method to capture these nutrients and prevent runoff. However, an increased understanding of ecosystem processes is needed to create more efficient SGIs. Past studies have shown that pl... | 2022 |