NOVEL - Alfredo A. Sadun Collection
 
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1 A Neuro-Ophthalmologist's View of RGC Apoptosis and NeuroprotectionSlide presentation with several microscopic images demonstrating cell death, LHON, AIDS. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Phosphopyruvate Hydratase; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber; Acquired Immunodeficiency Syndrome; Glaucoma. Presen...Text
2 AIDS: Neuro-Ophthalmologic ManifestationsDiscusses various neuro-opthalmological complications to which AIDS patients are prone, and results of experimental testing on rabbits using Pentoxifylline. Anatomy: Optic nerve; Axons; Optic disk; Astrocytes; Macrophages. Pathology: Slides showing astrocytes, macrophages, cytokine staining. Disease...Text
3 Accreditation and the RRCA slide presentation providing information on accreditation and the residency review committee (RRC).Text
4 Acute Retrobulbar Optical NeuropathyPPT covering acute retrobulbar optic neuropathy, including ischemic, inflammatory, anterior ischemic optic neuropathy (AION) and non-arteritic anterior ischemic optic neuropathy (NAION); includes brainscan images for optic neuritis and multiple sclerosis; optic disk with LHON and PION. Anatomy: Opt...Text
5 An Epidemic of Blindness in Cuba: Lessons on Nutrition and MitochondriaPresented at Stanford in April 2007, recapping the 1990s expedition to Cuba to investigate causes of blindness epidemic. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Ambliopia; Ataxia; Paresthesia; Hyporeflexia.Text
6 Anatomy and Physiology of Vision: The Visual PathwaysIntroduction to neuro-ophthalmology, covering the optic nerve, the afferent visual system (eye to brain), the pupil (Afferent-Efferent Reflex), and the efferent visual system (eye movements). Anatomy: Optic nerve; Optic disc; Retina; Retinal ganglion cells; Optic chiasm; Visual cortex. Disease/Diagn...Text
7 Anatomy and Physiology of the Optic NerveLecture covering the anatomy and physiology of the optic nerve. Covers the retina and anterior visual pathways. Several slides show microscopic images of optic nerve damage. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Cytokines. Disease/Diagnosis: Glaucoma.Text
8 Apoptosis in LHON: An ROS ExplanationA slide presentation describing apoptosis in LHON; includes several images of optic nerve and optic disk. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber.Text
9 Apoptosis of Retinal Ganglion CellsPresented at a conference on neuroprotection at Sedona, Arizona, 2002; includes several microscopic images demonstrating cell death. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Cytokines. Disease/Diagnosis: Glaucoma.Text
10 Are IV Steroids and Anti-Platelet Agents Indicated in Every Case of GCA?From a debate at a meeting in Canada in Sept. 2006, with Sadun taking the "pro" position. Disease/Diagnosis: Giant cell arteritis. Treatment: Methylprednisolone Hemisuccinate; Solumedrol; Prednisone; Aspirin.Text
11 Atypical Optic NeuropathiesA discussion of atypical optic neuropathies. Anatomy: Optic nerve; Optic disc. Pathology: Slides showing LHON. Disease/Diagnosis: Optic neuropathy, Ischemic; Optic atrophy, Hereditary, Leber; Toxic optic neuropathy. Presenting Symptom: Optic neuritis; Eye hemorrhage; Retinal vasculitis; Dyschromatop...Text
12 Beyond Visual Acuity: New Measures in the Evaluation of VisionUse of Amsler charts and 3-D computer imaging to evaluate visual acuity, sensitivity, and health. Disease/Diagnosis: Glaucoma; Age related macular degeneration. Presenting Symptom: Scotoma.Text
13 Beyond Visual Acuity: New Measures in the Evaluation of VisionUse of Amsler charts and 3-D computer imaging to evaluate visual acuity, sensitivity, and health. Disease/Diagnosis: Glaucoma; Age related macular degeneration. Presenting Symptom: Scotoma.Text
14 Beyond the Margulis Hypothesis: The Time Bomb Within UsPresented at Harvard, 2005; includes several images of optic disc with LHON. Anatomy: Optic nerve; Optic disk; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber. Presenting Symptom: Dyschromatopsia; Scotoma.Text
15 Beyond the Margulis Hypothesis: The Time Bomb Within UsPresented at 36th Annual Doheny Days, 2005. Anatomy: Optic nerve; Retina; Retinal ganglion cells; Reactive oxygen species. Disease/Diagnosis: Optic Atrophy, Hereditary, Leber.Text
16 Circadian Rhythms: How Much Retina Do We Need for a Good Night's Sleep?Discusses importance of the health of the retinohypothalamic tract in the maintenance of circadian rhythm. Anatomy: Retina; Hypothalamus; Retinal ganglion cells; Pineal gland. Disease/Diagnosis: Retinal diseases; Sleep disorders, Circadian rhythm.Text
17 Color Vision: Insights Into Our Origins and Some of Our Artists - From Darwin to DelacroixDiscussion of origins and physiology of color vision in different species, distinction between addition and subtraction of colors, and how painters get around the difference. Includes microscopic views of retinal cones. Anatomy: Retina; Rods (Retina); Cones (Retina).Text
18 Compressive Optic Neuropathies PotpourriAn overview of compressive optic neuropathies, including symptoms, varieties, testing, and treatments; slide presentation includes several neuroimaging scans. Anatomy: Optic nerve. Disease/Diagnosis: Compression of optic nerve. Treatment: MifepristoneText
19 Controversies - Anatomy and Treatment of DyslexiaA slide presentation on dyslexia.Text
20 Cortical Visual Phenomena (Anton's to Geschwind's)Part 6 of a course taught at Stanford University. Anatomy: Visual cortex. Disease/Diagnosis: Aphasia; Blindness, Cortical; Hallucinations, Visual; Anton's Syndrome; Visual Agnosia; Palinopsia; Geschwind's Syndrome; Apraxia; Cortical paralysis of fixation syndrome; Alzheimer's Syndrome.Text
21 Cuban Epidemic of Optic Neuropathy: Even Zealots Must Eat, or, Conversations with CastroA team of neuro-opthalmologists visits Cuba in 1993 and 1994, and attempts to treat patients with vision disorders. Anatomy: Optic nerve; Structure of cribriform plate. Disease/Diagnosis: Optic nerve diseases; Blindness; Ambliopia; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Ataxia;...Text
22 Cuban Epidemic of Optic Neuropathy: Even Zealots Must Eat, or, Conversations with CastroA team of neuro-opthalmologists visits Cuba in 1993 and 1994, and attempts to treat patients with vision disorders. Anatomy: Optic nerve. Disease/Diagnosis: Optic nerve diseases; Alcoholic neuropathy. Treatment: Folate. Presenting Symptom: Blindness; Ambliopia; Ataxia; Paresthesia; Hyporeflexia.Text
23 Cushing and OphthalmologyFrom a lecture at Yale in 2006, reviewing the life of Harvey Cushing, the founder of neurosurgery. Anatomy: Optic chiasm; Optic nerve. Disease/Diagnosis: Pituitary adenoma; Papilledema; X-linked hydrocephalus syndrome; Optic nerve glioma; Graves ophthalmopathy; Mucocele; Pituitary apoplexy; Optic ne...Text
24 Distinguishing Optic Nerve vs. Retinal LesionsPPT describing methods of distinguishing optic nerve verses retinal lesions. Describes a pateint case. Discussed signs, symtpoms and diagnostic tests. Anatomy: Optic nerve; Retina; Retinal macula. Disease/Diagnosis: Optic nerve diseases; Retinal lesion; Macular lesion; Disorder of the optic nerve; A...Text
25 Distinguishing an Optic Neuropathy from a MaculopathyPPT describing a case of optic neuropathy. Covers signs and symptoms, and various laboratory tests. Describes 10 signes of disc edema. Anatomy: Optic nerve; Retina; Retinal macula. Disease/Diagnosis: Optic nerve diseases; Retinal lesion; Macular lesion; Disorder of the optic nerve; Afferent pupillar...Text
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