Filters: School Or College:"School of Medicine" Publication Type:"thesis" Department:"Pathology" Collection:"ir_etd"
| Title | Author | Subject | Description | Date | ||
|---|---|---|---|---|---|---|
| 1 |  | A comparison of creatinine measurement by the Jaffe and enzymatic methods in an outpatient population | Adams, Austin Howard | Biochemistry; Medicine | Serum creatinine concentrations and estimated glomerular filtration rates (eGFR) are widely used for the evaluation of renal function. The Jaffe and enzymatic methods are the most common methods for creatinine measurement. The Jaffe method is commonly less expensive than enzymatic methods but may be... | 2014-12 |
| 2 |  | A correlation of the bacterial flora of the nasopharynx and the urinary tract to "Bacterial Allergy." | Kingston, T. Ray | Urinary Organs; Microbiology; Nasopharynx | Twelve cases of clinically diagnosed "bacterial allergy" were studied to determine the bacterial flora of the nasopharynx and of the urinary tract. A comparison of the types of bacteria formed in nasopharyngeal secretions and in the urine was made. It was found that in the majority of cases the sa... | 1951 |
| 3 |  | A member of the mycobiome modulates a host metabolite to increase intestinal permeability and disease | Chiaro, Tyson Richard | Microbiology; Immunology | The human body is a fascinating arrangement of cellular organization necessary to support life; it is also home to trillions of microorganisms. The largest concentration of these commensal microbes exists within the gastrointestinal tract (GI) where bacteria dominate the landscape. Accordingly, the ... | 2015-05 |
| 4 |  | A transgenic zebrafish model of signaling through toll-like receptors | Elsberry, Danielle | Health and environmental sciences; biological sciences; danio rerio; toll-like receptors; transgenic model; zebrafish | Toll-like receptors (TLRs), members of the innate immune system, recognize distinctive components of pathogens to initiate cellular signaling pathways. These pathways lead to the production of inflammatory proteins such as tumor necrosis factor alpha (TNFα), a cytokine that activates immune cells t... | 2011-05 |
| 5 |  | Activation of the apoptotic pathway in response to chemotherapy in childhood leukemia | Liu, Tong | Drug Therapy | Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. Although patients with ALL have benefited greatly from dramatic advances in chemotherapy, a substantial number of patients eventually fail to respond to treatment, and their prognosis is poor. Cytotoxic chemotherapeutic age... | 2000-05 |
| 6 |  | Adequacy of capillary lead specimens | Johnson, Nathan H. | Toxicity | In response to the increased demand for reliable alternatives to venous lead testing, the Centers for Disease Control has called for increased research into using capillary methodologies. In the past, there have been problems with this procedure, primarily because of external lead contamination fal... | 1995-08 |
| 7 |  | The affects of passaging strains of Mycoplasma arthritidis and Mycoplasma hominis, type 2, in the rat. | Rowland, Laura Golightly. | Llyophilization; Biochemical | Diphosphoglycerate (DPG) plays an integral part in the transport of oxygen to tissues. By binding reversibly with hemoglobin, DPG decreases hemoglobin's affinity for oxygen and increases oxygen availability to the tissues. Multiple factors affect the synthesis and binding ability of DPG and indire... | 1969-06 |
| 8 |  | Alpha-melanocyte stimulating hormone regulation of tumor necrosis factor and interleukin 1-indicible biologic responses | Robertson, Rebecca Anna | Inflammation; MSH; Neuropeptides | The effect of alpha-Melanocyte-Stimulating Hormone (alpha-MSH) on the ability of Interleukin 1 (IL-1) and Tumor Necrosis Factor (TNF) to mediate biologic responses was investigated. Initial experiments show that mice injected with either semi-purified IL-1or human recombinant IL-1beta demonstrate t... | 1989-06 |
| 9 |  | Alteration of murine mammary tumor metastasis and growth by cytomegalovirus infection | Olsen, Gregg Arden | Cellular, Viral, and Molecular Biology | Host resistance to the development of metastatic lesions is complex and involves both lymphocyte and macrophage functions. Studies in both humans and animals have suggested that cytomegalovirus infection may alter these components of the defense mechanism of the host. In the present study, an experi... | 1980-06 |
| 10 |  | Alternative treatment options for cryptococcal meningitis: the search for amphotericin B synergists | Clifford, Jeffrey Jordan | Cryptococcal meningitis; oseltamivir phosphate; immunosuppressed individuals | Cryptococcal meningitis is a fatal disease that is most commonly found in immunosuppressed individuals, particularly HIV patients. Initial treatment is with a combination of Amphotericin B (AmB) and 5-Flucytosine. 5-flucytosine is expensive and unavailable in many of the countries where the burden o... | 2019 |
| 11 |  | An audit of repeat testing at an academic medical center: consistency of order patterns with recommendations and potential cost savings | Hueth, Kyle Dean | Medicine; health sciences; health care management | We aimed to evaluate the prevalence of potentially unnecessary repeat testing (PURT) and the associated economic burden for an inpatient population at a large academic medical facility. For the target tests, we evaluated all inpatient test orders during 2016 for PURT by comparing the inter-test tim... | 2018 |
| 12 |  | An evaluation of mitochondrial DNA resequencing array mitochip version 2.0 in comparison with sanger sequencing | Xiao, Ye | Biological sciences; health and environmental sciences; MitoChip v2.0; mitochondria; mitochondrial disorders; Rrsequencing array | Mitochondrial disorders can be caused by defects in mitochondrial DNA (mtDNA) or nuclear DNA. The mitochondrial genome is a small double stranded circular DNA of 16,569 base pairs. Mitochondrial DNA insertions, deletions, and hundreds of point mutations have been reported to be associated with mitoc... | 2012-08 |
| 13 |  | Analysis of antibody responses to streptococcal and tissue antigens in patients with acute rheumatic fever | Martins, Thomas Bernd | Antigen-Antibody Reactions | Acute Rheumatic Fever (ARF) is an autoimmune disease occurring in individuals following untreated group A streptococcal infection believed to be triggered by antibodies to bacterial components that cross-react with human tissues. A multiplexed immunoassay was developed for the simultaneous quantita... | 2007-05 |
| 14 |  | Analysis of pilin polymerization in a uropathogenic Escherichia coli strain containing two pyelonephritis-associated (pap)gene clusters. | Wilkins, Diana Gaudin. | Microbiology; Urinary Organs; Polymers; Urinary Tract Infections | E. coli strain C1212 expresses two distinct pili on its cell surface that is encoded by separate pyelonephritis-associated pili (pap) gene clusters. These gene clusters have been demonstrated to produce expression of pili composed of either 17 kilodalton (kd) or 21 pilin monomers. The potential fo... | 1988-06 |
| 15 |  | Aspects of the ingestive and cytopeptic action of phagocytes. | Gyi, Ko Ko. | Mice; Spleen | 1. Total body x-irradiation of mice in doses of 300, 400, or 500 r does not affect the phagocytosis by reticuloendothelial cells of spleen of intravenously injected ThO2 when determined 2 day following x-irradiation. Similar studies carried out on the seventh post-irradiation day revealed (1) that ... | 1957-03 |
| 16 |  | Aspects of the relationship between irradiation injury and mammalian host defenses. | Donaldson, David Miller | Focal Infection; Physiological; Immunology | 1. Whole body x-irradiation of rabbits with doses of 650 r more results in a depression or loss of serum bactericidal action. 2. Total body irradiation of rats (600 r) and guinea pigs (350 r) results is in suppressed serum bactericidal action. This post irradiation depression in serum bactericida... | 1954 |
| 17 |  | Bacteriologic aspects of chronic pulmonary emphysema | Okawa, Ruthe A. | Microbiology; Ethylene Oxide | Although much work has been done by many investigators in the study of emphysema, the etiology and the pathogenesis of emphysema are still unknown. Therefore, a study was made to investigate the bacterial flora of patients with emphysema, to see if there was a species or strain of organisms peculi... | 1962-08 |
| 18 |  | BALB C mice: a novel model for borrelia burgdorferi-induced lyme arthritis | Fisher, Colleen Melissa | Biological sciences; health and environmental sciences | BALB/c mice have been used to study multiple diseases that cause inflammation such as Lyme arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Lyme disease or, more specifically, Lyme arthritis is caused by Borrelia burgdorferi that has disseminated into joint tissues. A spectrum of L... | 2017-08 |
| 19 |  | Basic studies on a new sugar-tolerant yeast. | Osman, Farouk Ahmed Ahmed. | Yeast; Nitrogen Fixation | 1. An osmohilic yeast strain was isolated from sugar syrup samples of high yeast count. The taxonomic characteristics of this yeast strain were determined. These characteristics showed that it is a new species of the genus Saccharomyces. 2. A series of experiments was conducted to investigate th... | 1965-06 |
| 20 |  | BRAF gene mutational analysis of the thyroid and correlation with clinicopathologic findings | Rowe, Leslie Rae | Polymerase Chain Reasction; DNA Sequencing Analysis; Cancer; Thyroid Carcinoma | Fine needle aspiration biopsy (FNA) cytology has been found to be an effective method for determining the likelihood of malignancy in patients with a thyroid nodule. However, an equivocal cytologic diagnosis is associated with approximately one-fifth of all thyroid FNAs. Recently, an activating poin... | 2005-08 |
| 21 |  | Candidate locus analysis for PHACE syndrome | Mitchell, Sheri Marie | biological sciences; health and environmental sciences; candidate locus analysis; hemangioma; phace | Posterior fossa malformations, large infantile hemangioma of the head neck or face, arterial cerebrovascular anomalies, cardiac anomalies, and eye anomalies define the acronym for PHACE syndrome. PHACE syndrome (OMIM no. 606519) is a neurocutaneous syndrome with unknown etiology and pathogenesis. We... | 2015-12 |
| 22 |  | Case study approach to health science: design and implementation of an online course | Newton, Kathryn Turner | Online Courses; Implementation; Technology | Distance education has evolved from traditional correspondence courses by mail to courses utilizing the latest developments in technology. With the advent of the Internet, distance education has grown exponentially. Internet-based courses add to the traditional advantages of distance education of e... | 2001-08 |
| 23 |  | Cellular immunity in tuberculosis | Maxwell, Kameron White | Immunology | The role of cellular immunity was studied using in vitro techniques for observing rates of phagocytosis and cytopepsis. Peritoneal exudates were stimulated using standard techniques and alveolar phagocytes were harvested by a technically less difficult method than used by others. This procedure yi... | 1966-06 |
| 24 |  | Certain immunological responses of wild rodents and laboratory animals following challenge with Pasteurella tularensis. | Lundgren, David Lee | Experimental Animals; Antigens | Five species of wild rodents native to the Great Salt Lake Basin have been found to produce a characteristic cutaneous response to intradermal injection of various Past. tularensis preparations, following challenge with viable Past. tularensis organisms. An area of in duration was produced which re... | 1961-05 |
| 25 |  | Characterization of dendritic cells for in vitro induction of T cell tolerance | Mahto, Subhashini | A major barrier to effective allogeneic bone marrow transplantation is Graft versus host disease (GVHD). Donor T cells are a recognized prerequisite for generation of GVHD. Dendritic cells (DCs) are the most powerful antigen-presenting cell (APC) in the immune system. The ability of DCs to stimul... | 2002-12 |