| | Creator | Title | Description | Subject | Date |
|---|
| 1 |  | Couldwell, William T. | Porous polyethylene implant for cranioplasty and skull base reconstruction | Object. Cranial reconstruction after skull base surgery is important for restoration of function and cosmesis. The authors describe their experience with the Medpor porous polyethylene implant for cosmetic cranioplasty and reconstruction after skull base surgery. Methods. Medpor, a biocompatible i... | | 2004 |
| 2 |  | Couldwell, William T. | Posterolateral approach for decompression with anterior and posterior fusion: a less invasive surgical technique for stabilization of the thoracic spine | The goals of surgery in unstable thoracic fractures or tumors involving the thoracic spine are neural decompression, correction of deformity, and stabilization. Several different approaches can be used to achieve these goals. The anterior, combined anterior and posterior, and more recently thoraco... | Decompression; Thoracic spine; Posterolateral approach | 1998 |
| 3 |  | Kestle, John R. W. | Potentially useful outcome measures for clinical research in pediatric neurosurgery | The choice of outcome (or outcomes) and their measurement are critical for a sound clinical trial. Surgeons have traditionally measured simple outcomes such as death, duration of survival, or tumor recurrence but have recently developed more sophisticated measures of the effect of an intervention. M... | Pediatric neurosurgery | 2005 |
| 4 |  | Kestle, John R. W. | Predicting shunt failure on the basis of clinical symptoms and signs in children | Object. In evaluating pediatric patients for shunt malfunction, predictive values for symptoms and signs are important in deciding which patients should undergo an imaging study, whereas determining clinical findings that correlate with a low probability of shunt failure could simplify management. ... | Pediatric Shunt Design Trial; PSDT; Shunt failure; Shunt malfunction; Clinical signs | 2001 |
| 5 |  | Kestle, John R. W. | Predicting slitlike ventricles in children on the basis of baseline characteristics at the time of shunt insertion | Object. Slit ventricle syndrome (SVS) is a delayed complication of shunt insertion and occurs only in children with slitlike ventricles after shunt placement. Although SVS appears to be related to early shunt placement, its predisposing factors are largely unknown. Methods. Baseline data in 737 chi... | Slitlike ventricles; Slit ventricle syndrome; Shunt insertion; Predictive factor; Ventriculoperitoneal shunt; Pediatric neurosurgery | 2007 |
| 6 |  | Couldwell, William T. | Predictive value of serum prolactin levels measured immediately after transsphenoidal surgery | Object. Prolactin-secreting pituitary adenomas may be managed by surgery, medication, radiotherapy, or observation. The authors reviewed a consecutive series of patients who were followed for at least 5 years after surgery to assess the prognostic significance of preoperative factors (tumor size and... | Prolactin; Transsphenoidal surgery; Pituitary adenoma; Prolactinoma; Transsphenoidal approach | 2002 |
| 7 |  | Kestle, John R. W. | Priorities for hydrocephalus research: report from a National Institutes of Health-sponsored workshop | Object. Treatment for hydrocephalus has not advanced appreciably since the advent of cerebrospinal fluid (CSF) shunts more than 50 years ago. Many questions remain that clinical and basic research could address, which in turn could improve therapeutic options. To clarify the main issues facing hydr... | Biomedical research | 2007 |
| 8 |  | Couldwell, William T. | Prognostic variables in surgery for skull base meningiomas | The authors have retrospectively analyzed selected surgical and pathological observations made among a group of 20 patients harboring recurrent cranial base meningiomas in an attempt to reveal which factors may be important in predicting tumor recurrence. This cohort was compared with a group of 3... | Skull base; Prognostic factor; Recurrence | 1997 |
| 9 |  | Couldwell, William T. | Prolactinomas: focus on indications, outcomes and management of recurrences | Although prolactinomas are discovered at autopsy with equal frequency in women and men, they present clinically in women far more often than in men. In children, "in whom they are the most common type of adenoma, prolactinomas are seen more often in girls than in boys. In a series of nearly 400 PRL... | Outcome; Pituitary adenoma; Prognosis; Prolactin; Transsphenoidal surgery | 1999 |
| 10 |  | Couldwell, William T. | Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase C | THE PROLIFERATION RATES of gliomas may be modulated by the protein kinase C (PKC) signal transduction system. The present study was undertaken to further examine the role of PKC system in growth regulation of gliomas in vitro by measurement of PKC activity over various phases of tumor growth and by ... | Protein kinase C; Brain neoplasms; Growth factor; Glioma; Phorbol ester | 1992 |
| 11 |  | Couldwell, William T. | Protein kinase C and growth regulation in malignant gliomas | To the Editor: The presence of amplified growth factor systems in many tumor models, including malignant gliomas, raises the question of how such external signals are transduced into a transformed phenotype (increased proliferation, invasion, lack of contact inhibition, angiogenic capacity, etc.). ... | Protein kinase C; Glioma; Brain neoplasm; protooncogenes; Apoptosis; Tamoxifen | 1994 |
| 12 |  | Couldwell, William T. | Protein kinase C inhibitors suppress cell growth in established and low-passage glioma cell lines. a comparison between staurosporine and tamoxifen | WE HAVE PREVIOUSLY demonstrated that the proliferation of established human glioma cell lines correlated with protein kinase C (PKC) activity and that a relatively selective PKC inhibitor, staurosporine, inhibits glioma cell proliferation. The purpose of this study was to determine whether low-passa... | Staurosporin; Tamoxifen; Protein kinase C; Glioma; Brain neoplasm; Glioma cell lines | 1993 |
| 13 |  | Dailey, Andrew T. | Thoracolumbar spine trauma classification: the Thoracolumbar Injury Classification and Severity Score system and case examples | Object. The aim of this study was to review the Thoracolumbar Injury Classification and Severity Score (TLICS) and to demonstrate its application through a series of spine trauma cases. Methods. The Spine Trauma Study Group collaborated to create and report the TLICS system. The TLICS system is re... | Thoracolumbar spine trauma; Classification; Thoracolumbar injury; TLICS; Spine Trauma Study Group; Thoracolumbar Injury Classification and Severity Score | 2009 |
| 14 |  | Schmidt, Meic H. | Thoracoscopic debridement and stabilization of pyogenic vertebral osteomyelitis | The role of surgical debridement and internal fixation in treatment of vertebral osteomyelitis has been evolving. The standard surgical approach to thoracolumbar vertebral osteomyelitis requiring extensive thoracotomy or retroperitoneal exposure carries significant associated morbidity and postoper... | | 2007-01-01 |
| 15 |  | Schmidt, Meic H. | Thoracoscopic spine surgery for decompression and stabilization of the anterolateral thoracolumbar spine | The anterior thoracolumbar spine can be exposed via a variety of approaches. Historically, open anterolateral or posterolateral approaches have been used to gain access to the anterior thoracolumbar spinal column. Although the exposure is excellent, open approaches are associated with significant pa... | Endoscopic spinal surgery; Thoracic spine; Lumbar spine; Thoracoscopic spinal instrumentation | 2005 |
| 16 |  | Schmidt, Meic H. | Thoracoscopic vertebral body replacement with an expandable cage after ventral spinal canal decompression | OBJECTIVE: Minimally invasive thoracic anterior surgery using a thoracoscopic approach has evolved to include spinal biopsy, debridement, discectomy, decompressive corpectomy, interbody fusions, and internal fixations. Minimal access techniques can potentially decrease surgical access morbidity and... | | 2007-01-01 |
| 17 |  | Dailey, Andrew T.; Brodke, Darrel S. | Timing and influence of MRI on the management of patients with cervical facet dislocations remains highly variable: a survey of members of the Spine Trauma Study Group | Background: Traumatic cervical facet dislocations are potentially devastating injuries. Magnetic resonance imaging (MRI) is an excellent means of assessing ligamentous disruption, disk herniation, and compression of the neural elements. However, despite an improved understanding of these facet dislo... | Cervical facet dislocations; MRI; Spine Trauma Study Group | 2009 |
| 18 |  | Schmidt, Meic H. | Titanium cage-assisted polymethylmethacrylate reconstruction for cervical spinal metastasis | Reconstruction and stabilization of the cervical spine after vertebrectomy is an important goal in the surgical management of spinal metastasis. The authors describe their reconstruction technique using a titanium cage-Silastic tube construct injected with polymethylmethacrylate (PMMA) augmented by... | Titanium cage; Cervical spine; Cervical spinal metastasis; Reconstruction; Vertebrectomy; PMMA reconstruction; Silastic tube | 2005 |
| 19 |  | Couldwell, William T. | Total intravenous anesthesia: advantages for intracranial surgery | Although volatile anesthetics have been widely accepted in anesthetic management for neurosurgery, they reduce vascular resistance, resulting in increased cerebral blood flow and increased intracranial pressure (ICP). In patients with elevated ICP who undergo craniotomy, the increase in ICP during s... | Anesthesia; Inhalants; Intravenous; Propofol; Intracranial surgery | 2007 |
| 20 |  | Couldwell, William T. | Transfacet pedicle-sparing approach for thoracic disc removal: cadaveric morphometric analysis and preliminary clinical experience | A number of operative techniques have been described for the treatment of herniated thoracic discs. The transfacet pedicle-sparing approach allows for complete disc removal with limited spinal column disruption and soft-tissue dissection. Fifteen cadaveric spinal columns were used for evaluation of... | Thoracic spine; Herniated thoracic discs; Intervertebral disc herniation; Discectomy; Pedicle; Radiculopathy; Myelopathy | 1998 |
| 21 |  | Couldwell, William T. | Transmaxillary approach to the anterior cavernous sinus: a microanatomic study | OBJECTIVE: Several approaches to expose the anterior cavernous sinus have been used, such as frontotemporal, orbitofrontal, anterior subtemporal, and various transfacial approaches. In an effort to gain exposure to the anterior cavernous sinus without necessitating a craniotomy or wide transfacial ... | Anterior cavernous sinus; Clivus; Cranial base; Maxillary sinus | 1997 |
| 22 |  | Couldwell, William T. | Transnasal excerebration surgery in ancient Egypt: Historical vignette | Ancient Egyptians were pioneers in many fields, including medicine and surgery. Our modern knowledge of anatomy, pathology, and surgical techniques stems from discoveries and observations made by Egyptian physicians and embalmers. In the realm of neurosurgery, ancient Egyptians were the first to elu... | | 2012-01-01 |
| 23 |  | Kestle, John R. W. | Response to editorial: summer shunting | We thank Dr. Scott for his review and comments about our report of shunt surgery complications in the summer. He makes two very good points. Clearly, different databases are suited for different purposes, and the NIS database used in the study by Smith and colleagues is well suited to evaluating t... | | 2006 |
| 24 |  | Couldwell, William T. | Comment on Aydin, K., et al: Localization of cerebrospinal fliud leaks by gadolinium-enhanced magnetic resonance cisternography: a 5-year single-center experience | The Author's describe the use of intrathecal Gd-enhanced MR cisternography for the definition of cerebrospinal fluid leaks in 51 patients. They were able to identify the site of leak in 43 of 51 patients (84%). Although the technique is not new, most of the previous articles are found in the neuror... | Cerebrospinal fluid leaks | 2007 |
| 25 |  | Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 10: fusion following decompression in patients with stenosis without spondylolisthesis | Standards. There is insufficient evidence to recommend a treatment standard. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. 1) In situ posterolateral lumbar fusion is not recommended as a treatment option in patients with lumbar stenosis in whom there is n... | Fusion; Lumbar spine; Degenerative disease; Lumbar fusion | 2005 |