Mast cell (lung, golden hamster)

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Title Mast cell (lung, golden hamster)
Creator Poels, Lambert G.
Contributor Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen
Date 2007-12-01
Description Electron microscopy. Mucosa mast cells (mastocytes) are frequently found perivascularly or perineurally. The mast cell shows long thin microvilli at the surface and the cytoplasm is stuffed with granules (1) varying in shape and size. At (2) a Golgi area and at (3) small mitochondria and some electron-dense lysosomes. The larger membrane-bound vesicles (so-called compound granules) show a metachromatic reaction in light microscopy and ultrastructurally a granule exhibits a heterogeneous content (different with species) e.g., osmiophilic granular, filamentous, whorl-like substances. The younger granules are less dense and show a more loosened reticular internal structure. The granules contain among others heparin, histamine, enzymes such as superoxide dismutase, beta-hexosaminidase, tryptase, factors such as neutrophil- and eosinophil-chemotactic factors, vasoactive mediators.
Subtype Image
Format image/jpeg
Collection Poja Histology Collection - Blood & Bone Marrow Subset
ARK ark:/87278/s6cv7m13
Setname ehsl_heal
Date Created 2012-12-11
Date Modified 2012-12-11
ID 891135
Reference URL
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