Mast cell (connective tissue, human)

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Title Mast cell (connective tissue, human)
Creator Poels, Lambert G.
Contributor Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen
Date 2007-12-01
Description Electron microscopy. Mast cells (mastocytes) are frequently found perivascularly or perineurally within the connective tissue. A detail of this mast cell shows granules varying in shape and size. These membrane-bound vesicles (so-called compound granules) show a metachromatic reaction in light microscopy and ultrastructurally a granule exhibits a heterogeneous content (different with species). The internal substructure is composed of osmiophilic short parallel stalks (1) in a granular substance appearing in cross-sections as scroll-like or whorl-like figures (2). Scroll-like as well as whorl-like substructures are common in human mastocytes. At thin arrows (↓) the boundaries of some granules. These granules contain among others heparin, histamine, enzymes such as superoxide dismutase, beta-hexosaminidase, tryptase, factors such as neutrophil- and eosinophil-chemotactic factors, vasoactive mediators.
Subtype Image
Format image/jpeg
Collection Poja Histology Collection - Blood & Bone Marrow Subset
ARK ark:/87278/s6d250wg
Setname ehsl_heal
Date Created 2012-12-11
Date Modified 2012-12-11
ID 891104
Reference URL
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