Complete hydatidiform mole (human)

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Title Complete hydatidiform mole (human)
Creator Poels, Lambert G.
Contributor Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen
Subject trophoblast; complete hydatidiform mole; placenta; villus; immunohistochemistry; keratin-7
Description Stain: (A) Hematoxylin-eosin. (B+C) Immunoperoxidase staining with diaminobenzidin (DAB) and hematoxylin counterstaining for keratin 7 (OVTL 12-30 antibody). (A)Trophoblast cells surround the dilated chorionic villi (1), with centrally large amounts of edematous mesenchymal stroma with almost no blood vessels. The villus lining shows irregular proliferation resulting in large solid cell masses (2). (B+C) Keratin 7-staining is distinct for lining syncytiotrophoblast cells (3) and strongly positive for proliferating ones while lining cytotrophoblast cells appear negatively (arrows).
Subtype Image
Format image/jpeg
Rights http://creativecommons.org/licenses/by-nc-nd/3.0/
Collection Poja Histology Collection - Placenta
ARK ark:/87278/s66t3px5
Setname ehsl_heal
ID 890819
Reference URL https://collections.lib.utah.edu/ark:/87278/s66t3px5
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