Keratin 7 staining in squamous metaplasia of the epithelium of a bronchiolus (human, adult)

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Title Keratin 7 staining in squamous metaplasia of the epithelium of a bronchiolus (human, adult)
Creator Poels, Lambert G.
Contributor Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen
Date 2006-09-28
Subject Bronchiolus; Squamous metaplasia; Immunoperoxidase; Immuno-reaction
Description Stain: anti-keratin 7 antibody (Pan-Ck 7) immunoperoxidase staining (with aminoethylcarbazole (AEC) substrate). A red-brown staining with AEC indicates a positive reaction for cytokeratin 7. Note that the top layer only is stained positively for keratin 7 (↓). Upon squamous metaplasia the bronchiolar epithelial cells reduce keratin 7 expression and hence this cytokeratin appears a suitable marker in the study of early metaplastic processes in epithelia e.g., the bronchial tree.
Subtype Image
Format image/jpeg
Rights http://creativecommons.org/licenses/by-nc-nd/2.5/
Collection Poja Histology Collection - Respiratory System Subset
ARK ark:/87278/s62g0qq2
Setname ehsl_heal
Date Created 2012-12-11
Date Modified 2012-12-11
ID 890766
Reference URL https://collections.lib.utah.edu/ark:/87278/s62g0qq2
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