Microfluidic devices for rapid and sensitive identification of organisms

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Publication Type pre-print
School or College College of Engineering
Department Mechanical Engineering
Creator Gale, Bruce K.
Other Author Samuel, R.; Jayamohan, H.; Sant, H.
Title Microfluidic devices for rapid and sensitive identification of organisms
Date 2014-01-01
Description Microfluidic devices for rapid and highly sensitive detection of living organisms were developed for two applications. First, a zebrafish embryo genotyping system was developed and shown to be able to genotype embryos in the first 48 hours of the embryos life without damaging the embryos in any apparent way. Second, a highly sensitive bacteria detection platform has been eveloped for the rapid detection of pathogens. The system relies on a magnetic bead extraction followed by secondary bead attachment. The secondary beads are barcoded with DNA sequences highly enriched for Gs. The guanine molecules generate an electorchemical response after they are released from the secondary beads and detected at a sensing location downstream from the beads. The amplification with the efficient washing procedures leads to a limit of detection of 3 CFU in 100 mL of water.
Type Text
Publisher Institute of Electrical and Electronics Engineers (IEEE)
First Page 774
Last Page 777
Language eng
Bibliographic Citation Gale, B. K., Samuel, R., Jayamohan, H., & Sant, H. (2014). Microfluidic devices for rapid and sensitive identification of organisms. 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 774-7.
Rights Management (c) 2014 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
Format Medium application/pdf
Format Extent 803,690 bytes
Identifier uspace,19422
ARK ark:/87278/s63z1gwx
Setname ir_uspace
Date Created 2016-02-02
Date Modified 2016-02-02
ID 713345
Reference URL https://collections.lib.utah.edu/ark:/87278/s63z1gwx
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