Multi-object analysis of volume, pose, and shape using statistical discrimination

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Publication Type pre-print
School or College <blank>
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Creator Gerig, Guido
Other Author Gorczowski, Kevin.; Styner, Martin; Jeong, Ja Yeon; Marron, J. S.; Piven, Joseph; Hazlett, Heather Cody; Pizer, Stephen M.
Title Multi-object analysis of volume, pose, and shape using statistical discrimination
Date 2010-01-01
Description One goal of statistical shape analysis is the discrimination between two populations of objects. Whereas traditional shape analysis was mostly concerned with single objects, analysis of multi-object complexes presents new challenges related to alignment and pose. In this paper, we present a methodology for discriminant analysis of multiple objects represented by sampled medial manifolds. Non-euclidean metrics that describe geodesic distances between sets of sampled representations are used for alignment and discrimination. Our choice of discriminant method is the distance-weighted discriminant because of its generalization ability in high-dimensional, low sample size settings. Using an unbiased, soft discrimination score, we associate a statistical hypothesis test with the discrimination results. We explore the effectiveness of different choices of features as input to the discriminant analysis, using measures like volume, pose, shape, and the combination of pose and shape. Our method is applied to a longitudinal pediatric autism study with 10 subcortical brain structures in a population of 70 subjects. It is shown that the choices of type of global alignment and of intrinsic versus extrinsic shape features, the latter being sensitive to relative pose, are crucial factors for group discrimination and also for explaining the nature of shape change in terms of the application domain.
Type Text
Publisher Institute of Electrical and Electronics Engineers (IEEE)
Volume 32
Issue 4
First Page 652
Last Page 661
Language eng
Bibliographic Citation Gorczowski, K., Styner, M., Jeong, J. Y., Marron, J. S., Piven, J., Hazlett, H. C., Pizer, S. M., & Gerig, G. (2010). Multi-object analysis of volume, pose, and shape using statistical discrimination. IEEE Trans Pattern Anal Mach Intell, 32(4), 652-61.
Rights Management (c) 2010 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
Format Medium application/pdf
Format Extent 1,243,605 bytes
Identifier uspace,19207
ARK ark:/87278/s6f50z8f
Setname ir_uspace
Date Created 2015-01-30
Date Modified 2015-01-30
ID 712793
Reference URL https://collections.lib.utah.edu/ark:/87278/s6f50z8f
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