Intermuscular fat: a review of the consequences and causes

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Publication Type pre-print
School or College School of Medicine
Department Physical Therapy
Creator LaStayo, Paul C.
Other Author Addison, Odessa; Marcus, Robin L.; Ryan, Alice S.
Title Intermuscular fat: a review of the consequences and causes
Date 2014-01-01
Description Muscle's structural composition is an important factor underlying muscle strength and physical function in older adults. There is an increasing amount of research to support the clear disassociation between the loss of muscle lean tissue mass and strength with aging. This disassociation implies that factors in addition to lean muscle mass are responsible for the decreases in strength and function seen with aging. Intermuscular adipose tissue (IMAT) is a significant predictor of both muscle function and mobility function in older adults and across a wide variety of comorbid conditions such as stroke, spinal cord injury, diabetes, and COPD. IMAT is also implicated in metabolic dysfunction such as insulin resistance. The purpose of this narrative review is to provide a review of the implications of increased IMAT levels in metabolic, muscle, and mobility function. Potential treatment options to mitigate increasing levels of IMAT will also be discussed.
Type Text
Publisher Hindawi Publishing Corporation
First Page 1
Last Page 12
Language eng
Bibliographic Citation Addison, O., Marcus, R. L., Lastayo, P. C., & Ryan, A. S. (2014). Intermuscular fat: a review of the consequences and causes. International Journal of Endocrinology, 309570, 1-12.
Rights Management (c) Paul C. LaStayo
Format Medium application/pdf
Format Extent 2,272,819 bytes
Identifier uspace,18475
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Setname ir_uspace
ID 712048
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