Hypophysial transposition (hypophysopexy) for radiosurgical treatment of pituitary tumors involving the cavernous sinus

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Publication Type Journal Article
School or College School of Medicine
Department Neurosurgery
Creator Couldwell, William T.; Schmidt, Meic H.; MacDonald, Joel D.; Jensen, Randy L.
Other Author Liu, James K.
Title Hypophysial transposition (hypophysopexy) for radiosurgical treatment of pituitary tumors involving the cavernous sinus
Date 2003
Description Stereotactic radiosurgery (SRS) is performed with increasing frequency in the treatment of residual or recurrent pituitary adenomas. Its major associated risk in these cases of residual or recurrent pituitary tumor adjacent to normal functional pituitary gland is radiation exposure to the pituitary, which frequently leads to the development of hypopituitarism. The authors describe a technique of pituitary transposition to reduce the radiation dose to the normal pituitary gland in cases of planned radiosurgical treatment of residual pituitary adenoma within the cavernous sinus. A sellar exploration for tumor resection is performed, the pituitary gland is transposed from the region of the cavernous sinus, and a fat and fascia graft is interposed between the normal pituitary gland and the residual tumor in the cavernous sinus. The residual tumor may then be treated with SRS. The increased distance between the normal pituitary gland and the residual tumor facilitates treatment of the tumor with radiosurgery and reduces radiation exposure to the normal pituitary gland.
Type Text
Publisher American Association of Neurological Surgeons (AANS)
Volume 14
Issue 5
Subject Pituitary tumor; Cavernous sinus; Hypopituitarism; Stereotactic radiosurgery; Transsphenoidal surgery; Pituitary transposition
Subject LCSH Radiosurgery; Pituitary gland -- Diseases; Pituitary gland -- Wounds and injuries
Subject MESH Pituitary Neoplasms; Hypopituitarism; Radiosurgery
Language eng
Bibliographic Citation Liu, J. K., Schmidt, M. H., MacDonald, J. D., Jensen, R. L., & Couldwell, W. T. (2003). Hypophysial transposition (hypophysopexy) for radiosurgical treatment of pituitary tumors involving the cavernous sinus. Neurosurgical Focus, 14(5), e11.
Rights Management (c) American Association of Neurological Surgeons
Format Medium application/pdf
Format Extent 430,028 bytes
Identifier ir-main,12604
ARK ark:/87278/s6z89x10
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Reference URL https://collections.lib.utah.edu/ark:/87278/s6z89x10
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