Invasive sinonasal disease due to Scopulariopsis candida: case report and review of scopulariopsosis.

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Publication Type Journal Article
School or College School of Medicine
Department Ophthalmology; Internal Medicine; Pediatrics
Creator Kriesel, John D.; Gooch, Willis M.; Pavia, Andrew T.
Other Author Adderson, E. E.
Title Invasive sinonasal disease due to Scopulariopsis candida: case report and review of scopulariopsosis.
Date 1994
Description Sinonasal infection with fungi of the order Mucorales--termed mucormycosis or zygomycosis--is sometimes seen in immunosuppressed patients, including those with diabetic ketoacidosis and malignancy. We describe a case of invasive sinonasal infection with Scopulariopsis candida (not among the Mucorales organisms) in a 12-year-old girl who was being treated for non-Hodgkin's lymphoma. Only a few cases of invasive infection with Scopulariopsis species have been reported previously; five of six of these cases were associated with persistent or fatal disease. Our patient survived without undergoing radical surgical debridement and was treated with granulocyte colony-stimulating factor, amphotericin B, and itraconazole; chemotherapy was stopped. In vitro susceptibility testing of our patient's Scopulariopsis isolate showed that it was resistant to amphotericin B and that it was relatively susceptible to itraconazole and miconazole. The case described herein demonstrates the expanding spectrum of fungal organisms that may cause invasive sinonasal infection in immunocompromised hosts and the need for reliable antifungal susceptibility testing.
Type Text
Publisher University of Chicago Press
Volume 19
Issue 2
First Page 317
Last Page 319
Subject Granulocyte Colony-Stimulating Factor; Itraconazole; Maxillary Sinus
Subject MESH Mycoses; Mitosporic Fungi; Paranasal Sinus Diseases
Language eng
Bibliographic Citation Kriesel JD, Adderson EE, Gooch WM 3rd, Pavia AT. (1994). Invasive sinonasal disease due to Scopulariopsis candida: case report and review of scopulariopsosis. Clin Infect Dis, 19(2), 317-9.
Rights Management (c) University of Chicago Press http://www.journals.uchicago.edu/loi/cid
Format Medium application/pdf
Identifier ir-main,1771
ARK ark:/87278/s68s57hf
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2012-06-13
ID 706976
Reference URL https://collections.lib.utah.edu/ark:/87278/s68s57hf
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