Pattern of protein synthesis in monkey cells infected by simian virus 40

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Publication Type Journal Article
School or College School of Medicine; College of Science; College of Engineering
Department Bioengineering; Biology; Human Genetics
Creator Gesteland, Raymond F.
Other Author Anderson, Carl, W.
Title Pattern of protein synthesis in monkey cells infected by simian virus 40
Date 1972
Description After infection of several permanent monkey cell lines by simian virus 40 (SV40), four additional protein bands can be detected by simple sodium dodecyl sulfate-polyacrylamide gel electrophoresis of whole-cell extracts. These bands appear only after the onset of viral deoxyribonucleic acid (DNA) synthesis, and inhibitors of DNA synthesis prevent their appearance. Three of them correspond to three previously identified capsid components, VP1, VP2, and VP3. The fourth protein band, which does not correspond to a previously identified virion component, is induced by SV40 infection of CV-1 and BSC-1 cultures but not by infection of MA-134 cultures.
Type Text
Publisher American Society for Microbiology
Volume 9
Issue 5
First Page 758
Last Page 765
Subject Monkeys; Simian virus 40; Peptides; DNA, Viral/biosynthesis
Subject MESH Simian virus 40; Viral Proteins; Time Factors; DNA Replication/drug effects; Amino Acid Sequence
Language eng
Bibliographic Citation Anderson, C. W. & Gesteland, R. F. (1972). Pattern of protein synthesis in monkey cells infected by simian virus 40. Journal of Virology, 9(5), 758-65.
Rights Management ©American Society for Microbiology
Format Medium application/pdf
Identifier ir-main,12740
ARK ark:/87278/s62r4956
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2013-02-27
ID 706289
Reference URL https://collections.lib.utah.edu/ark:/87278/s62r4956
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