Modeling the amplification dynamics of human Alu retrotransposons

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Publication Type Journal Article
School or College College of Social & Behavioral Science
Department Anthropology
Creator Rogers, Alan R.; Jorde, Lynn B.
Other Author Hedges, Dale J.; Cordaux, Richard; Xing, Jinchuan; Witherspoon, David J.; Batzer, M. A.
Title Modeling the amplification dynamics of human Alu retrotransposons
Date 2005
Description Retrotransposons have had a considerable impact on the overall architecture of the human genome. Currently, there are three lineages of retrotransposons (Alu, L1, and SVA) that are believed to be actively replicating in humans. While estimates of their copy number, sequence diversity, and levels of insertion polymorphism can readily be obtained from existing genomic sequence data and population sampling, a detailed understanding of the temporal pattern of retrotransposon amplification remains elusive.
Type Text
Publisher Public Library of Science (PLoS)
Volume 1
Issue 4
First Page 333
Last Page 340
Subject Retrotransposons; Amplification dynamics; Mutation; Human-chimpanzee divergence
Subject LCSH Transposons; Human genome
Language eng
Bibliographic Citation Hedges, D. J., Cordaux, R., Xing, J., Witherspoon, D. J., Rogers, A. R., Jorde, L. B., & Batzer, M. A. (2005). Modeling the amplification dynamics of human Alu retrotransposons. PLoS Computational Biology, 1(4), 0333-40.
Rights Management (c)Dale J. Hedges, Richard Cordaux, Jinchuan Xing, David J. Witherspoon, Alan R. Rogers, Lynn B. Jorde, and Mark A. Batzer
Format Medium application/pdf
Format Extent 59,911 bytes
Identifier ir-main,7889
ARK ark:/87278/s6n594wv
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2021-05-06
ID 706186
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