| Publication Type |
Journal Article |
| School or College |
College of Science |
| Department |
Biology |
| Creator |
Olivera, Baldomero M.; Gray, William Robert; Yoshikami, Doju |
| Other Author |
Cruz, Lourdes J.; Zeikus, Regina D.; Kerr, Lynne; Moczydlowski, Edward |
| Title |
Conus geographus toxins that discriminate between neuronal and muscle sodium channels |
| Date |
1985 |
| Description |
We describe the properties of a family of 22-amino acid peptides, the μ-conotoxins, which are useful probes for investigating voltage-dependent sodium channels of excitable tissues. The μ-conotoxins are present in the venom of the piscivorous marine snail, Conus geographus L. We have purified even homologs of the μ-conotoxin set and determined their amino acid sequences, as follows, where Hyp = trans-4-hydroxyproline. |
| Type |
Text |
| Publisher |
American Society for Biochemistry and Molecular Biology (ASBMB) |
| Volume |
260 |
| Issue |
16 |
| First Page |
9280 |
| Last Page |
9288 |
| Subject |
Conus geographus; Venom; Conotoxins; Sodium channels; Neurotoxins |
| Subject LCSH |
Neurotoxic agents; Neuropeptides; Conus |
| Language |
eng |
| Bibliographic Citation |
Cruz, L. J., Gray, W. R., Olivera, B. M., Zeikus, R. D., Kerr, L., Yoshikami, D., & Moczydlowski, E. (1985). Conus geographus toxins that discriminate between neuronal and muscle sodium channels. Journal of Biological Chemistry, 260(16), 9280-8. |
| Rights Management |
(c)American Society for Biochemistry and Molecular Biology (ASBMB) http://www.asbmb.org/ |
| Format Medium |
application/pdf |
| Format Extent |
2,462,835 bytes |
| Identifier |
ir-main,8208 |
| ARK |
ark:/87278/s6gj02f1 |
| Setname |
ir_uspace |
| ID |
705604 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6gj02f1 |
