Risk of preterm birth across generations.

Update item information
Publication Type Journal Article
School or College School of Medicine
Department Pediatrics; Obstetrics & Gynecology
Creator Varner, Michael W.; Porter T. Flint
Other Author Fraser, Alison M.; Hunter, Cheri Y.; Ward, Ryk H.
Title Risk of preterm birth across generations.
Date 1997-07
Description OBJECTIVE: To examine the risk of preterm birth for mothers who themselves were born before term. METHODS: Data were taken from a linked data base of birth certificates composed of two cohorts: 1) a parental cohort of women born between 1947 and 1957 and 2) their offspring born between 1970 and 1992. "Preterm mothers" were women in the parental cohort who were born at less than 37 weeks' gestation. "Term mothers" were women in the parental cohort born at or after 38 weeks' gestation. Preterm mothers and term mothers were matched for birth year, county of birth, marital status, parity, and age. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated for the risk of preterm delivery in preterm mothers. Multiple logistic regression was used to assess the interaction of concomitant variables with the risk of premature delivery. RESULTS: The risk of preterm birth was significantly higher in preterm mothers than in term mothers (OR 1.18; 95% CI 1.02, 1.37). The risk increased as the gestational age at the mothers' birth decreased (less than 30 weeks'; OR 2.38; 95% CI 1.37, 4.16). The interaction between maternal age and parity increased the risk of preterm delivery at less than 34 weeks in some age and parity strata. CONCLUSION: An increased risk of preterm delivery exists for women who themselves were born before 37 weeks' gestation. The risk is inversely correlated with the maternal gestational age at birth and is influenced by maternal age and parity.
Type Text
Publisher Lippincott, Williams & Wilkins
Volume 90
Issue 1
First Page 63
Last Page 67
Subject Preterm mothers; Pregnancy; Premature; Risk
Subject MESH Gestational Age; Obstetric Labor, Premature
Language eng
Bibliographic Citation Porter TF, Fraser AM, Hunter CY, Ward RH, Varner MW. The risk of preterm birth across generations. Obstet Gynecol. 1997 Jul;90(1):63-7. Retrieved on April 17, 2007 from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=Display&DB=pubmed
Rights Management Copyright © Wolters Kluwer, Obstetrics and Gynecology, 90, 63-7. 1997
Format Medium application/pdf
Identifier ir-main,945
ARK ark:/87278/s673789q
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2020-05-07
ID 704813
Reference URL https://collections.lib.utah.edu/ark:/87278/s673789q
Back to Search Results