A-superfamily of conotoxins: structural and functional divergence

Update Item Information
Publication Type Journal Article
School or College College of Science
Department Biology
Creator Olivera, Baldomero M.; McIntosh, J. Michael; Hillyard, David R.
Other Author Santos, Ameurfina D.; Cruz, Lourdes J.
Title A-superfamily of conotoxins: structural and functional divergence
Date 2004-02-03
Description The generation of functional novelty in proteins encoded by a gene superfamily is seldom well documented. In this report, we define the A-conotoxin superfamily, which is widely expressed in venoms of the predatory cone snails (Conus), and show how gene products that diverge considerably in structure and function have arisen within the same superfamily.
Type Text
Publisher American Society for Biochemistry and Molecular Biology (ASBMB)
Journal Title Journal of Biological Chemistry
Volume 279
Issue 17
First Page 17596
Last Page 17606
DOI 10.1074/jbc.M309654200
citatation_issn 0021-9258
Subject Conotoxins; A-superfamily conotoxin
Subject LCSH Conus; Marine toxins; Conus -- Genetics
Language eng
Bibliographic Citation Santos, A. D.; McIntosh, J. M.; Hillyard, D. R.; Cruz, L. J.; Olivera, B. M. (2004). A-superfamily of conotoxins: structural and functional divergence. Journal of Bilogical Chemistry, 279(17), 17596-606.
Rights Management (c)American Society for Biochemistry and Molecular Biology (ASBMB) http://www.asbmb.org/
Format Medium application/pdf
Format Extent 926,310 bytes
Identifier ir-main,8432
ARK ark:/87278/s6np2nqb
Setname ir_uspace
ID 704360
Reference URL https://collections.lib.utah.edu/ark:/87278/s6np2nqb
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