Major histocompatibility complex-dependent susceptibility to Cryptococcus neoformans in mice

Update item information
Publication Type Journal Article
School or College College of Science
Department Biology
Creator Potts, Wayne K.; Granger, Donald Lee
Other Author McClelland, Erin E.
Title Major histocompatibility complex-dependent susceptibility to Cryptococcus neoformans in mice
Date 2003
Description To evaluate the role of major histocompatibility complex (MHC) genes in the resistance to Cryptococcus neoformans, we conducted infection experiments in MHC-congenic strains of mice. Significant MHC-dependent susceptibility differences were found among homozygotes and heterozygotes. This study is the first experimental demonstration of MHC-dependent susceptibility to C. neoformans infections in mice and indicates that MHC genes can be important in host resistance.
Type Text
Publisher American Society for Microbiology
Volume 71
Issue 8
First Page 4815
Last Page 4817
Subject MHC-congenic; Host resistance; Infection
Dissertation Institution University of Utah
Language eng
Bibliographic Citation McClelland, E. E., Granger, D. L., & Potts, W. K. (2003). Major histocompatibility complex-dependent susceptibility to Cryptococcus neoformans in mice. Infection and Immunity, 71(8), Aug., 4815-7.
Rights Management (c)American Society for Microbiology
Format Medium application/pdf
Format Extent 64,357 bytes
Identifier ir-main,6010
ARK ark:/87278/s6h428q1
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2013-02-07
ID 704132
Reference URL https://collections.lib.utah.edu/ark:/87278/s6h428q1
Back to Search Results