Functional reorganization of primary visual cortex induced by electrical stimulation in the cat.

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Publication Type Journal Article
School or College School of Medicine; College of Engineering
Department Ophthalmology; Bioengineering; Surgery; Physiology
Creator Normann, Richard A.
Other Author Warren, David J.
Title Functional reorganization of primary visual cortex induced by electrical stimulation in the cat.
Date 2005
Description Compared to the high degree of plasticity observed in a juvenile, mature sensory cortices have long been held to be immutable but, recently, researchers have suggested some plasticity persists in the mature cortex. Cortical reorganization has particular saliency to the development of a cortically based, sensory neuroprosthesis, which will chronically evoke activity through electrical stimulation. We have examined the nature and extent of the reorganization induced by electrical stimulation. We found the receptive field size and synaptic efficacy can be increased, particularly for neurons near the stimulation site. As the changes are minimal, these results are not expected to impact neuroprosthetic applications.
Type Text
Publisher Cambridge University Press
Volume 45
Issue 5
First Page 551
Last Page 565
Subject Cat; Electrophysiology; Phosphene; Plasticity; Receptive Field; Striate Cortex
Subject MESH Brain Mapping; Cats; Electric Stimulation; Neuronal Plasticity; Visual Cortex
Language eng
Bibliographic Citation Warren DJ, Normann RA. (2005). Functional reorganization of primary visual cortex induced by electrical stimulation in the cat. Vision Res, 45(5), 551-65
Rights Management © Cambridge University Press
Format Medium application/pdf
Identifier ir-main,12755
ARK ark:/87278/s6rb7nvh
Setname ir_uspace
ID 703811
Reference URL https://collections.lib.utah.edu/ark:/87278/s6rb7nvh
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