Segregation and overlap of callosal and association neurons in frontal and parietal cortices of primates: a spectral and coherency analysis.

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Publication Type Journal Article
School or College School of Medicine
Department Ophthalmology
Creator Angelucci, Alessandra
Other Author Johnson, P B; Ziparo, R M; Minciacchi, D; Bentivoglio M; Caminiti, R
Title Segregation and overlap of callosal and association neurons in frontal and parietal cortices of primates: a spectral and coherency analysis.
Date 1989
Description The spatial relations between selected classes of association and callosal neurons were studied in the frontal and parietal lobes of the macaque monkey using retrogradely transported fluorescent dyes. Fast blue and nuclear yellow were injected in the left frontal (areas 4 and 6) and right posterior parietal (area 5) cortices, respectively. These injections led to the retrograde labeling, in the right frontal cortex, of callosal neurons projecting homotopically and association neurons projecting to ipsilateral area 5; in the left superior parietal lobule, of callosal neurons projecting to contralateral area 5 and association neurons projecting to the ipsilateral frontal lobe. In both frontal and parietal cortices, callosal and association neurons were located in layers III and V-VI; a few neurons were also found in layer II. The contribution of layers V-VI to the callosum was significantly higher in areas 4 and 6 than in area 5. Only a small number of neurons (less than 1%) were double labeled. Spectral analyses were used to characterize the spatial periodicities of the distributions of callosal and association neurons. In areas 4, 6, and 5, both association and callosal spectra were dominated by a strong elevation in the range of low spatial frequencies, corresponding to periodicities in cell density with a peak-to-peak distance of about 8 mm. This indicated an arrangement of these corticocortical cells in the form of bands. The latter displayed various shapes and orientations and were composed of more discrete assemblies of cell clusters of about 400-1000 microns width. Their presence was revealed in the power spectra by a small elevation in the range of high spatial frequencies. The coherency analysis assessed the degree of linear relationships for each spatial frequency, and therefore the degree of similarity, between callosal and association cell distributions, together with their phase relations. Little coherency was found in areas 4 and 6 between bands of callosal and association neurons, which suggests that the 2 cell populations are differently and independently distributed in the tangential domain, with no simple phase relations. The overall mean coherency was higher in area 5 than in the frontal cortex: callosal and association bands were more similar in shape, with more extensive zones of overlap. These data indicate that callosal and association neurons share common principles of spatial organization despite the great regional variability of their interrelations in the tangential cortical domain.
Type Text
Publisher Society for Neuroscience
Volume 9
Issue 7
First Page 2313
Last Page 2326
Subject Macaca fascicularis; Parietal Lobe; Neurons
Subject MESH Corpus Callosum; Frontal Lobe; Neural Pathways
Language eng
Bibliographic Citation Johnson PB, Angelucci A, Ziparo RM, Minciacchi D, Bentivoglio M, Caminiti R. (1989). Segregation and overlap of callosal and association neurons in frontal and parietal cortices of primates: a spectral and coherency analysis. J Neurosci, 9(7), 2313-26.
Rights Management (c) Society for Neuroscience
Format Medium application/pdf
Identifier ir-main,1776
ARK ark:/87278/s6ww81wn
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2012-06-13
ID 703247
Reference URL https://collections.lib.utah.edu/ark:/87278/s6ww81wn
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