Complications of anesthesia for cesarean delivery.

Update item information
Publication Type Journal Article
School or College School of Medicine
Department Pediatrics; Obstetrics & Gynecology
Creator Varner, Michael W.
Other Author Bloom, Steven L.; Spong, Catherine Y.; Weiner, Steven J.; Landon, Mark B.; Rouse, Dwight J.; Moawad, Atef H.; Caritis, Steve N.; Harper, Margaret; Wapner, Ronald J.; Sorokin, Yoram; Miodovnik, Menachem; O'Sullivan, Mary J.; Sibai, Baha; Langer, Oded; Gabbe, Steven G.; National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.
Title Complications of anesthesia for cesarean delivery.
Date 2005-08
Description OBJECTIVE: To quantify anesthesia-related complications associated with cesarean delivery in a well-described, prospectively ascertained cohort from multiple university-based hospitals in the United States and to evaluate whether certain factors would identify women at increased risk for a failed regional anesthetic. METHODS: A prospective observational study was conducted of women (n = 37,142) with singleton gestations undergoing cesarean delivery in the centers forming the National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Detailed information was collected regarding choice of anesthesia and procedure-related complications, including failed regional anesthetic and maternal death. Potential risk factors for a failed regional anesthetic were analyzed. RESULTS: Of the women studied, 34,615 (93%) received a regional anesthetic. Few (3.0%) regional procedures failed, and related maternal morbidity was rare. Increased maternal size, higher preoperative risk, rapid decision-to-incision interval, and placement later in labor were all significantly related to an increased risk of a failed regional procedure. Of the general anesthetics, 38% were administered when the decision-to-incision interval was less than 15 minutes. Women deemed at the greatest preoperative risk (American Society of Anesthesiologists score > or = 4) were approximately 7-fold more likely to receive a general anesthetic (odds ratio 6.9, 95% confidence interval 5.83-8.07). There was one maternal death, due to a failed intubation, in which the anesthetic procedure was directly implicated. CONCLUSION: Regional techniques have become the preferred method of anesthesia for cesarean delivery. Procedure-related complications are rare and attest to the safety of modern obstetric anesthesia for cesarean delivery in the United States.
Type Text
Publisher Lippincott, Williams & Wilkins
Volume 106
Issue 2
First Page 281
Last Page 287
Subject Cesarean Section; Complications of Anesthesia
Subject MESH Cesarean Section; Pregnancy Outcome; Anesthesia
Language eng
Bibliographic Citation Bloom SL, Spong CY, Weiner SJ, Landon MB, Rouse DJ, Varner MW, Moawad AH, Caritis SN, Harper M, Wapner RJ, Sorokin Y, Miodovnik M, O'Sullivan MJ, Sibai B, Langer O, Gabbe SG; National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Complications of anesthesia for cesarean delivery. Obstet Gynecol. 2005 Aug;106(2):281-7. Retrieved on April 20, 2007 from
Rights Management Copyright © Wolters Kluwer, Obstetrics and Gynecology, 105, 281-7, 2005
Format Medium application/pdf
Identifier ir-main,958
ARK ark:/87278/s6891q1m
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2021-05-06
ID 703045
Reference URL
Back to Search Results