Decidual, amniotic fluid, maternal and fetal prolactin in normal and abnormal pregnancies.

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Publication Type Journal Article
School or College School of Medicine
Department Pediatrics; Obstetrics & Gynecology
Creator Varner, Michael W.
Other Author Luciano, Anthony A.
Title Decidual, amniotic fluid, maternal and fetal prolactin in normal and abnormal pregnancies.
Date 1984-03
Description In the present studies, the content and the in vitro production of prolactin by decidua as well as the concentrations of prolactin in amniotic fluid, maternal and fetal serum in normal term pregnancies, induced abortions at various gestational ages, and in pregnancies complicated by diabetes mellitus, preeclampsia, chronic hypertension, and polyhydramnios were measured. Maternal and fetal prolactin levels varied considerably throughout gestation, but at term did not differ significantly between normal and abnormal pregnancies. Prolactin levels in amniotic fluid as well as decidual prolactin content and production were significantly lower only in pregnancies complicated by either hypertension or polyhydramnios. In both normal and abnormal pregnancies, decidual prolactin production correlated strongly with amniotic fluid concentrations. The present data suggest that 1) maternal and fetal prolactin levels do not differ significantly between normal and abnormal pregnancies, 2) the decidua is the principal source of amniotic fluid prolactin, and 3) the significantly lower levels of prolactin in amniotic fluid of pregnancies complicated by hypertension or polyhydramnios are probably due to adverse effects of these conditions on the synthesis and release of prolactin by decidua.
Type Text
Publisher Lippincott, Williams & Wilkins
Volume 63
Issue 3
First Page 384
Last Page 388
Subject Decidual; Amniotic Fluid; Prolactin; Pregnancy Complications
Subject MESH Decidua/*secretion; Amniotic Fluid;Prolactin/*analysis/blood; Pregnancy Complications
Language eng
Bibliographic Citation Luciano AA, Varner MW. Decidual, amniotic fluid, maternal and fetal prolactin in normal and abnormal pregnancies. Obstet Gynecol. 1984 Mar;63(3):384-8. Retrieved on April 25th, 2007 from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=Display&DB=pubmed
Rights Management Copyright © Wolters Kluwer, Obstetrics and Gynecology, 63, 384-8, 1984.
Format Medium application/pdf
Identifier ir-main,996
ARK ark:/87278/s6xh087h
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2012-06-13
ID 702742
Reference URL https://collections.lib.utah.edu/ark:/87278/s6xh087h
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