Castleman disease of the spine mimicking a nerve sheath tumor

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Publication Type Journal Article
School or College School of Medicine
Department Neurosurgery
Creator Schmidt, Meic H.
Other Author Finn, Michael A.
Title Castleman disease of the spine mimicking a nerve sheath tumor
Date 2007
Description Castleman disease is a rare lymphoproliferative disease of unknown cause. In most cases, afflicted patients present with a mediastinal mass although the disease may manifest in numerous other sites, including intracranially and rarely intraspinally. The authors report on the case of a 19-year-old woman who presented with a large paraspinal mass emanating from the T7-8 neural foramen. The morphological and signal characteristics revealed on magnetic resonance imaging were similar to those of nerve sheath tumors. The patient underwent open biopsy sampling of the lesion, and results of a pathological evaluation revealed hyaline-vascular type Castleman disease. She underwent radiotherapy and remains symptom-free with a radiographically stable lesion 1 year later. Although the disease has been reported to mimic a meningioma when encountered in intracranial locations, to the authors' knowledge, this is the first case of the disorder mimicking a nerve sheath tumor. When the diagnosis of Castleman disease is made, good results can be obtained with partial resection and radiotherapy.
Type Text
Publisher American Association of Neurological Surgeons (AANS)
Volume 6
Issue 5
First Page 455
Last Page 459
Subject Castleman disease; Nerve sheath tumor
Subject LCSH Spine -- Diseases; Lymph nodes -- Diseases; Spine -- Surgery
Language eng
Bibliographic Citation Finn, M. A., & Schmidt, M. H. (2007). Castleman disease of the spine mimicking a nerve sheath tumor. Case report. Journal of Neurosurgery: Spine, 6(5), 455-9.
Rights Management (c) American Association of Neurological Surgeons
Format Medium application/pdf
Format Extent 1,272,959 bytes
Identifier ir-main,12790
ARK ark:/87278/s6mk6x0d
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2021-05-06
ID 702461
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