Development and performance evaluation of a tandem mass spectrometry assay for 4 adrenal steroids

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Publication Type Journal Article
Department Pathology
Program ARUP Institute for Clinical and Experimental Pathology
Creator Owen, William E.; Rockwood, Alan L.; Roberts, William L.; Meikle, A. Wayne
Other Author Kushnir, Mark M.; Pattison, Elizabeth G.; Bunker, Ashley M.
Title Development and performance evaluation of a tandem mass spectrometry assay for 4 adrenal steroids
Date 2006
Description Congenital adrenal hyperplasia is a group of autosomal recessive disorders caused by a deficiency of 1 of 4 enzymes required for the synthesis of glucocorticoids, mineralocorticoids, and sex hormones. Analysis of 11-deoxycortisol (11DC), 17-hydroxyprogesterone (17OHP), 17-hydroxypregnenolone (17OHPr), and pregnenolone (Pr) in blood allows detection of these enzyme defects.
Type Text
Publisher American Association for Clinical Chemistry
Volume 52
Issue 8
First Page 1559
Last Page 1567
Subject Congenital adrenal hyperplasia; Adrenal steroids; Tandem mass spectrometry assay
Subject LCSH Mass spectrometry; Adrenocortical hormones
Language eng
Bibliographic Citation Kushnir, M. M., Rockwood, A. L., Roberts, W. L., Pattison, E. G., Owen, W. E., Bunker, A. M., & Meikle, A. W. (2006). Development and performance evaluation of a tandem mass spectrometry assay for 4 adrenal steroids. Clinical Chemistry, 52(8), 1559-67.
Rights Management (c)American Association for Clinical Chemistry
Format Medium application/pdf
Format Extent 227,654 bytes
Identifier ir-main,11547
ARK ark:/87278/s6s760c8
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2012-06-13
ID 702279
Reference URL https://collections.lib.utah.edu/ark:/87278/s6s760c8
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