Primary Sinonasal Undifferentiated Carcinoma Presenting with Bilateral Retrobulbar Optic Neuropathy

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Title Journal of Neuro-Ophthalmology, September 2007, Volume 27, Issue 3
Date 2007-09
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-5890
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s68087qb
Setname ehsl_novel_jno
ID 225618
Reference URL https://collections.lib.utah.edu/ark:/87278/s68087qb

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Title Primary Sinonasal Undifferentiated Carcinoma Presenting with Bilateral Retrobulbar Optic Neuropathy
Creator Tamhankar, M. A.; Volpe, N. J.; Loevner, L. A.; Palmer, J. N.; Feldman, M.
Affiliation Division of Neuro-ophthalmology, Scheie Eye Institute, Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, 51 North 39th Street, Philadelphia, PA 19104, USA.
Abstract A 43-year-old man presented with acute bilateral visual loss. Ophthalmologic examination revealed no light perception in the right eye and a visual acuity of 20/50 in the left eye with a right afferent pupillary defect. Ophthalmoscopic examination was normal. Brain MRI showed an intracranial but extra-axial mass in the floor of the anterior cranial fossa extending along the olfactory groove and into the sinonasal vault. Endoscopic biopsy showed a high-grade neoplasm consistent with sinonasal undifferentiated carcinoma. This case report highlights an unusual clinical presentation for this rare and aggressive neoplasm.
Subject Adult; Antineoplastic Combined Chemotherapy Protocols, therapeutic use; Biopsy; Carcinoma, complications; Carcinoma, pathology; Carcinoma, physiopathology; Cranial Fossa, Anterior, pathology; Cranial Fossa, Anterior, physiopathology; Fatal Outcome; Functional Laterality; Humans; Magnetic Resonance Imaging; Male; Nasal Cavity, pathology; Nasal Cavity, physiopathology; Neoplasm Metastasis, pathology; Optic Nerve, pathology; Optic Nerve, physiopathology; Optic Nerve Diseases, etiology; Optic Nerve Diseases, pathology; Optic Nerve Diseases, physiopathology; Orbit, pathology; Orbit, physiopathology; Paranasal Sinus Neoplasms, complications; Paranasal Sinus Neoplasms, pathology; Paranasal Sinus Neoplasms, physiopathology; Paranasal Sinuses, pathology; Paranasal Sinuses, physiopathology; Radiotherapy; Treatment Failure; Tumor Markers, Biological; Vision, Low, etiology; Vision, Low, pathology; Vision, Low, physiopathology
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Format application/pdf
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-5890
Setname ehsl_novel_jno
ID 225609
Reference URL https://collections.lib.utah.edu/ark:/87278/s68087qb/225609
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