Internuclear Ophthalmoplegia (INO) in multiple sclerosis

Update item information
Identifier INO_MS
Title Internuclear Ophthalmoplegia (INO) in multiple sclerosis
Subject Internuclear Ophthalmoplegia, Abnormal Saccades, Gaze Evoked Nystagmus
Creator Daniel R. Gold, DO, Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, Emergency Medicine, and Medicine, The Johns Hopkins School of Medicine
Description This video includes 3 patients each with a known history of MS found to have unilateral or bilateral INOs on their exam. In the first 2 patients, the INOs are relatively subtle with normal adduction. However, with rapid horizontal saccades, an adduction lag is apparent which is suggestive of an INO. Occasionally a pseudo-INO can be seen in the setting of myasthenia, due to relative medial rectus weakness that exacerbates with repeated horizontal saccades (i.e., it fatigues). Because some of the fibers responsible for vertical gaze holding travel through the MLF, upbeat nystagmus in upgaze is common with bilateral MLF lesions. Number of Videos and legend for each: 1, This video shows 3 patients with MS and INOs.
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Type Image/MovingImage
Format video/mp4
Relation is Part of NOVEL: Neuro-ophthalmology Virtual Education Library Examination Collection
Rights Management Copyright 2016. For further information regarding the rights to this collection, please visit:
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E, SLC, UT 84112-5890
Collection Neuro-ophthalmology Virtual Education Library: NOVEL
ARK ark:/87278/s6tj1wb3
Setname ehsl_novel_gold
Date Created 2016-09-14
Date Modified 2021-09-21
ID 187742
Reference URL
Back to Search Results