Walsh & Hoyt: Subacute Sensory Neuronopathy

A pure sensory neuronopathy can occur as a neurologically isolated remote effect of cancer, but it more often develops in the setting of a more extensive paraneoplastic encephalomyelitis. Isolated paraneoplastic subacute sensory neuronopathy is most often associated with small-cell lung cancer, but it also occurs in patients with multiple myeloma, Hodgkins disease, diffuse large cell lymphoma, other cancers of the lung, and carcinomas of the breast, ovary, and gastrointestinal tract.