Identifier |
20160229_nanos_sciplatform1_04 |
Title |
Pupillary Light Reaction in Pre-Clinical Alzheimer's Disease vs. Normal Aging Controls (.pdf) |
Creator |
Gregory P. Van Stavern, Ying-Bo Shui, Ling Bei, Julie Huecker, Mae Gordon, Fang Bai |
Subject |
Pupillometry, Alzheimer's Disease, Ocular Biomarkers |
Description |
Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognitive deficits and visual dysfunction. Neural biomarkers such as PET-Pib imaging and CSF ABeta levels are predictive of future development of AD but are expensive and cumbersome. There is increasing interest in using ocular biomarkers as a surrogate for disease activity in AD1. Several studies have shown that the pupillary light response (PLR) can differentiate AD patients from healthy controls. However, many of these studies assessed the PLR in established AD, and failed to control for systemic diseases and medications which affect the PLR. The PLR in preclinical AD remains poorly studied. |
Date |
2016-02-29 |
Language |
eng |
Format |
application/pdf |
Format Creation |
application/pdf |
Type |
Text |
Relation is Part of |
NANOS Annual Meeting 2016: Scientific Platform Session I |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
ARK |
ark:/87278/s6283ff7 |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Contributor Primary |
Gregory P. Van Stavern |
Contributor Secondary |
Ying-Bo Shui, Ling Bei, Julie Huecker, Mae Gordon, Fang Bai |
Setname |
ehsl_novel_nam |
ID |
185315 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6283ff7 |