Historical Trends in the Diagnosis of Peduncular Hallucinosis (.pdf)

Peduncular Hallucinosis (PH) refers to dream-like visual hallucinations during wakefulness that are typically caused by a focal lesion in the rostral brainstem. The conventional understanding of PH is that associated eye movement abnormalities are frequently, if not always, present. However, in the era of modern neuroimaging, PH has been increasingly diagnosed in patients without any objective deficits on physical examination. We sought to determine how modern neuroimaging has impacted the diagnosis of PH.