Neural Cell Adhesion Molecules in Acute Optic Neuritis: Relation to Clinical and Paraclinical Findings (.pdf)

Acute optic neuritis (AON) is an inflammatory condition of the optic nerve presumably of autoimmune origin. More than 50 % develop multiple sclerosis (MS). AON patients were chosen to achieve a homogenous patient group in which complete diagnostic work up was performed within one month from onset. No studies have thus far investigated the levels of Neural Cell Adhesion Molecules (NCAM) in the CSF in AON to determine whether NCAM is associated with demographic and paraclinical findings suggestive of MS.